Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs

Spermatozoa harbour a complex and environment-sensitive pool of small non-coding RNAs (sncRNAs) 1 , which influences offspring development and adult phenotypes 1 – 7 . Whether spermatozoa in the epididymis are directly susceptible to environmental cues is not fully understood 8 . Here we used two di...

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Bibliographic Details
Published in:	Nature (London) Vol. 630; no. 8017; pp. 720 - 727
Main Authors:	Tomar, A., Gomez-Velazquez, M., Gerlini, R., Comas-Armangué, G., Makharadze, L., Kolbe, T., Boersma, A., Dahlhoff, M., Burgstaller, J. P., Lassi, M., Darr, J., Toppari, J., Virtanen, H., Kühnapfel, A., Scholz, M., Landgraf, K., Kiess, W., Vogel, M., Gailus-Durner, V., Fuchs, H., Marschall, S., Hrabě de Angelis, M., Kotaja, N., Körner, A., Teperino, R.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 20.06.2024 Nature Publishing Group
Subjects:	38/39 45/90 631/208/176 631/443/319/333/1465 64/60 82/51 Body fat Body mass index Body size Diet Embryos Epididymis Epigenetics Fertilization Gametocytes Germ cells Glucose High fat diet Humanities and Social Sciences Insulin resistance Metabolism Mitochondria Mitochondrial DNA multidisciplinary Obesity Offspring Overweight Phenotyping Physiology Science Science (multidisciplinary) Sperm Spermatogenesis Spermatozoa Transcriptomics Transfer RNA
ISSN:	0028-0836, 1476-4687, 1476-4687
Online Access:	Get full text
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