Neural signal propagation atlas of Caenorhabditis elegans

Establishing how neural function emerges from network properties is a fundamental problem in neuroscience 1 . Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the hea...

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Veröffentlicht in:	Nature (London) Jg. 623; H. 7986; S. 406 - 414
Hauptverfasser:	Randi, Francesco, Sharma, Anuj K., Dvali, Sophie, Leifer, Andrew M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 09.11.2023 Nature Publishing Group
Schlagworte:	14/19 14/35 14/63 14/69 631/1647/2253 631/1647/245/2225 631/378/116/2392 631/378/3920 639/766/747 64/11 Anatomy Animals Body measurements Caenorhabditis elegans Caenorhabditis elegans - anatomy & histology Caenorhabditis elegans - cytology Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Calcium Calcium - analysis Calcium - metabolism Calcium imaging Humanities and Social Sciences Models, Neurological multidisciplinary Mutation Nematodes Nervous system Neural Pathways - physiology Neuroimaging Neurons Neurons - metabolism Neurons - physiology Neuropeptides Neuropeptides - metabolism Propagation Science Science (multidisciplinary) Signal Transduction - physiology Structure-function relationships Synapses - metabolism
ISSN:	0028-0836, 1476-4687, 1476-4687
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Abstract	Establishing how neural function emerges from network properties is a fundamental problem in neuroscience 1 . Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients—often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Measurements of signal propagation in more than 23,000 pairs of neurons from nematode worms show that predictions of neural function made on the basis of anatomy are often incorrect, in part owing to the effects of extrasynaptic signalling.
AbstractList	Establishing how neural function emerges from network properties is a fundamental problem in neuroscience . Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients-often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Establishing how neural function emerges from network properties is a fundamental problem in neuroscience 1 . Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients—often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Establishing how neural function emerges from network properties is a fundamental problem in neuroscience1. Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients-often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function.Establishing how neural function emerges from network properties is a fundamental problem in neuroscience1. Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients-often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Establishing how neural function emerges from network properties is a fundamental problem in neuroscience1. Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients—often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Measurements of signal propagation in more than 23,000 pairs of neurons from nematode worms show that predictions of neural function made on the basis of anatomy are often incorrect, in part owing to the effects of extrasynaptic signalling. Establishing how neural function emerges from network properties is a fundamental problem in neuroscience1. Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head ofthe nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatoryorinhibitory), strength, temporal properties and causal direction of signal propagation between these neuronsto create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-corevesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients-often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Establishing how neural function emerges from network properties is a fundamental problem in neuroscience 1 . Here, to better understand the relationship between the structure and the function of a nervous system, we systematically measure signal propagation in 23,433 pairs of neurons across the head of the nematode Caenorhabditis elegans by direct optogenetic activation and simultaneous whole-brain calcium imaging. We measure the sign (excitatory or inhibitory), strength, temporal properties and causal direction of signal propagation between these neurons to create a functional atlas. We find that signal propagation differs from model predictions that are based on anatomy. Using mutants, we show that extrasynaptic signalling not visible from anatomy contributes to this difference. We identify many instances of dense-core-vesicle-dependent signalling, including on timescales of less than a second, that evoke acute calcium transients—often where no direct wired connection exists but where relevant neuropeptides and receptors are expressed. We propose that, in such cases, extrasynaptically released neuropeptides serve a similar function to that of classical neurotransmitters. Finally, our measured signal propagation atlas better predicts the neural dynamics of spontaneous activity than do models based on anatomy. We conclude that both synaptic and extrasynaptic signalling drive neural dynamics on short timescales, and that measurements of evoked signal propagation are crucial for interpreting neural function. Measurements of signal propagation in more than 23,000 pairs of neurons from nematode worms show that predictions of neural function made on the basis of anatomy are often incorrect, in part owing to the effects of extrasynaptic signalling.
Author	Dvali, Sophie Sharma, Anuj K. Randi, Francesco Leifer, Andrew M.
Author_xml	– sequence: 1 givenname: Francesco orcidid: 0000-0002-6200-7254 surname: Randi fullname: Randi, Francesco organization: Department of Physics, Princeton University, Regeneron Pharmaceuticals – sequence: 2 givenname: Anuj K. orcidid: 0000-0001-5061-9731 surname: Sharma fullname: Sharma, Anuj K. organization: Department of Physics, Princeton University – sequence: 3 givenname: Sophie orcidid: 0000-0001-8565-7148 surname: Dvali fullname: Dvali, Sophie organization: Department of Physics, Princeton University – sequence: 4 givenname: Andrew M. orcidid: 0000-0002-5362-5093 surname: Leifer fullname: Leifer, Andrew M. email: leifer@princeton.edu organization: Department of Physics, Princeton University, Princeton Neurosciences Institute, Princeton University
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/37914938$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1038/nature12354 10.1523/JNEUROSCI.12-04-01394.1992 10.1371/journal.pone.0274226 10.1126/sciadv.ade1249 10.1126/science.274.5293.1724 10.7554/eLife.19887 10.1016/j.neuron.2011.09.027 10.1371/journal.pcbi.1005517 10.1038/s41586-019-1352-7 10.1364/OE.16.022039 10.1523/JNEUROSCI.2916-15.2015 10.1371/journal.pone.0024666 10.1002/neu.10014 10.1126/science.2321027 10.7554/eLife.56942 10.1016/j.cell.2020.08.010 10.1038/nmeth.3217 10.1038/s41598-018-26288-6 10.1038/nmeth.1397 10.1002/ana.20368 10.1371/journal.pcbi.1007974 10.1016/j.cell.2020.12.012 10.1103/PhysRevE.89.052805 10.1073/pnas.1530509100 10.7554/eLife.66410 10.1016/j.cell.2017.10.041 10.1016/j.jneumeth.2010.01.011 10.1146/annurev.ne.14.030191.000351 10.1038/nature24056 10.7554/eLife.66135 10.1016/j.neuron.2011.09.005 10.1016/j.cell.2015.02.018 10.1016/j.conb.2014.04.010 10.1523/JNEUROSCI.05-04-00956.1985 10.1016/j.cell.2015.09.034 10.1103/PhysRevLett.126.118102 10.1038/nn1891 10.1073/pnas.1507110112 10.1038/s41586-021-03778-8 10.7554/eLife.47889 10.1371/journal.pcbi.1005283 10.1016/j.cell.2021.06.023 10.1073/pnas.0409009101 10.3389/fncom.2017.00053 10.1073/pnas.1507109113 10.1016/j.cell.2014.09.056 10.1073/pnas.1106617108 10.1016/0896-6273(94)90283-6 10.1016/j.celrep.2023.113058 10.1007/s10158-008-0068-4 10.1073/pnas.0907084106 10.1098/rstb.2017.0374 10.3389/fendo.2012.00167 10.1534/g3.118.200158 10.1534/genetics.118.301705 10.3389/fncir.2014.00028 10.1016/j.neuron.2014.12.061 10.1007/BF01068419 10.1038/s41586-019-1772-4 10.1038/nn.3866 10.1038/ncomms13697 10.7554/eLife.37017 10.1523/JNEUROSCI.1466-07.2007 10.1016/j.ymeth.2017.03.023 10.1523/JNEUROSCI.16-12-04017.1996 10.1016/j.cub.2022.06.039 10.1002/cne.902610305 10.1895/wormbook.1.108.1 10.1101/2020.08.21.260984 10.1101/2022.10.30.514396 10.1101/2023.08.03.551820
ContentType	Journal Article
Copyright	The Author(s) 2023 2023. The Author(s). Copyright Nature Publishing Group Nov 9, 2023
Copyright_xml	– notice: The Author(s) 2023 – notice: 2023. The Author(s). – notice: Copyright Nature Publishing Group Nov 9, 2023
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DOI	10.1038/s41586-023-06683-4
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References	Meinecke, Peters (CR44) 1987; 261 Vaaga, Borisovska, Westbrook (CR11) 2014; 29 Witvliet (CR6) 2021; 596 Stern, Kirst, Bargmann (CR46) 2017; 171 Yu (CR58) 2021; 10 Chalfie (CR7) 1985; 5 Kunert-Graf, Shlizerman, Walker, Kutz (CR9) 2017; 11 Isaacson, Scanziani (CR43) 2011; 72 Arous, Tanizawa, Rabinowitch, Chatenay, Schafer (CR32) 2010; 187 Li, Liu, Zheng, Xu (CR60) 2014; 159 Monsalve, Yamamoto, Ward (CR61) 2019; 211 Storey, Tibshirani (CR40) 2003; 100 White, Southgate, Thomson, Brenner (CR1) 1986; 314 Mesulam (CR2) 2005; 57 Zhou (CR70) 2018; 8 Franconville, Beron, Jayaraman (CR22) 2018; 7 Jones, Sattelle (CR39) 2008; 8 Frooninckx (CR74) 2012; 3 CR4 Harris-Warrick, Marder (CR16) 1991; 14 Wicks, Roehrig, Rankin (CR30) 1996; 16 Lin (CR28) 2023; 9 Hallinen (CR68) 2021; 10 Hardaker, Singer, Kerr, Zhou, Schafer (CR29) 2001; 49 Lim (CR54) 2016; 5 Faumont (CR33) 2011; 6 Gordus, Pokala, Levy, Flavell, Bargmann (CR45) 2015; 161 Cook (CR5) 2019; 571 Yemini (CR27) 2021; 184 Uzel, Kato, Zimmer (CR41) 2022; 32 Chen (CR26) 2013; 499 Wang (CR36) 2020; 9 Gray, Hill, Bargmann (CR8) 2005; 102 Packer, Russell, Dalgleish, Häusser (CR20) 2015; 12 Randi, Leifer (CR55) 2021; 126 Kato (CR35) 2015; 163 Nguyen, Linder, Plummer, Shaevitz, Leifer (CR69) 2017; 13 van Vreeswijk, Sompolinsky (CR42) 1996; 274 Nguyen (CR62) 2016; 113 Nguyen (CR67) 2015; 113 CR57 Rickgauer, Tank (CR65) 2009; 106 Quintin, Aspert, Ye, Charvin (CR25) 2022; 17 Shipley, Clark, Alkema, Leifer (CR34) 2014; 8 Fisher, Lu, D’Alessandro, Wilson (CR15) 2019; 576 CR51 Denk, Strickler, Webb (CR64) 1990; 248 Beets (CR52) 2023; 42 Rickgauer, Deisseroth, Tank (CR19) 2014; 17 Kunert, Shlizerman, Kutz (CR47) 2014; 89 Bhatla, Horvitz (CR24) 2015; 85 Fenyves, Szilágyi, Vassy, Söti, Csermely (CR37) 2020; 16 Guo, Hart, Ramanathan (CR18) 2009; 6 Smith (CR50) 2019; 8 Izquierdo, Beer (CR73) 2018; 373 Venkatachalam (CR63) 2016; 113 Johnson (CR13) 1994; 12 Abbott (CR3) 2020; 182 Taylor (CR38) 2021; 184 Speese (CR53) 2007; 27 O’Malley, Sandell, Masland (CR12) 1992; 12 Petreanu, Huber, Sobczyk, Svoboda (CR17) 2007; 10 Emiliani, Cohen, Deisseroth, Haeusser (CR21) 2015; 35 CR23 CR66 Narayan, Laurent, Sternberg (CR48) 2011; 108 Noma, Jin (CR56) 2018; 8 Bentley (CR49) 2016; 12 Yan (CR10) 2017; 550 Yoo (CR14) 2016; 7 Papagiakoumou, Sars, Oron, Emiliani (CR71) 2008; 16 Schuirmann (CR72) 1987; 15 Kawano (CR31) 2011; 72 Paix, Folkmann, Seydoux (CR59) 2017; 121–122 M Chalfie (6683_CR7) 1985; 5 N Bhatla (6683_CR24) 2015; 85 Y Wang (6683_CR36) 2020; 9 JP Nguyen (6683_CR62) 2016; 113 JP Nguyen (6683_CR67) 2015; 113 L Frooninckx (6683_CR74) 2012; 3 A Paix (6683_CR59) 2017; 121–122 Z Zhou (6683_CR70) 2018; 8 LF Abbott (6683_CR3) 2020; 182 T-W Chen (6683_CR26) 2013; 499 KM Hallinen (6683_CR68) 2021; 10 JP Nguyen (6683_CR69) 2017; 13 DM O’Malley (6683_CR12) 1992; 12 LA Hardaker (6683_CR29) 2001; 49 SR Wicks (6683_CR30) 1996; 16 K Uzel (6683_CR41) 2022; 32 MA Lim (6683_CR54) 2016; 5 J Kunert (6683_CR47) 2014; 89 GC Monsalve (6683_CR61) 2019; 211 W Denk (6683_CR64) 1990; 248 A Lin (6683_CR28) 2023; 9 DL Meinecke (6683_CR44) 1987; 261 SJ Cook (6683_CR5) 2019; 571 BG Fenyves (6683_CR37) 2020; 16 A Gordus (6683_CR45) 2015; 161 MD Johnson (6683_CR13) 1994; 12 V Emiliani (6683_CR21) 2015; 35 JS Isaacson (6683_CR43) 2011; 72 EJ Izquierdo (6683_CR73) 2018; 373 Z Li (6683_CR60) 2014; 159 RM Harris-Warrick (6683_CR16) 1991; 14 SR Taylor (6683_CR38) 2021; 184 B Bentley (6683_CR49) 2016; 12 JB Arous (6683_CR32) 2010; 187 ZV Guo (6683_CR18) 2009; 6 JG White (6683_CR1) 1986; 314 D Witvliet (6683_CR6) 2021; 596 A Narayan (6683_CR48) 2011; 108 6683_CR4 FB Shipley (6683_CR34) 2014; 8 I Beets (6683_CR52) 2023; 42 JM Kunert-Graf (6683_CR9) 2017; 11 F Randi (6683_CR55) 2021; 126 JP Rickgauer (6683_CR65) 2009; 106 S Quintin (6683_CR25) 2022; 17 JH Yoo (6683_CR14) 2016; 7 R Franconville (6683_CR22) 2018; 7 G Yan (6683_CR10) 2017; 550 X Yu (6683_CR58) 2021; 10 E Papagiakoumou (6683_CR71) 2008; 16 DJ Schuirmann (6683_CR72) 1987; 15 6683_CR23 S Kato (6683_CR35) 2015; 163 E Yemini (6683_CR27) 2021; 184 M Mesulam (6683_CR2) 2005; 57 6683_CR66 JP Rickgauer (6683_CR19) 2014; 17 6683_CR51 YE Fisher (6683_CR15) 2019; 576 C van Vreeswijk (6683_CR42) 1996; 274 JM Gray (6683_CR8) 2005; 102 JD Storey (6683_CR40) 2003; 100 V Venkatachalam (6683_CR63) 2016; 113 L Petreanu (6683_CR17) 2007; 10 AK Jones (6683_CR39) 2008; 8 T Kawano (6683_CR31) 2011; 72 S Speese (6683_CR53) 2007; 27 S Stern (6683_CR46) 2017; 171 K Noma (6683_CR56) 2018; 8 SJ Smith (6683_CR50) 2019; 8 6683_CR57 AM Packer (6683_CR20) 2015; 12 S Faumont (6683_CR33) 2011; 6 CE Vaaga (6683_CR11) 2014; 29
References_xml	– volume: 113 start-page: E1074 year: 2015 end-page: E1081 ident: CR67 article-title: Whole-brain calcium imaging with cellular resolution in freely behaving publication-title: Proc. Natl Acad. Sci. USA – volume: 499 start-page: 295 year: 2013 end-page: 300 ident: CR26 article-title: Ultrasensitive fluorescent proteins for imaging neuronal activity publication-title: Nature doi: 10.1038/nature12354 – volume: 12 start-page: 1394 year: 1992 end-page: 1408 ident: CR12 article-title: Co-release of acetylcholine and GABA by the starburst amacrine cells publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.12-04-01394.1992 – ident: CR4 – volume: 17 start-page: e0274226 year: 2022 ident: CR25 article-title: Distinct mechanisms underlie H O sensing in head and tail publication-title: PLoS ONE doi: 10.1371/journal.pone.0274226 – volume: 9 start-page: eade1249 year: 2023 ident: CR28 article-title: Functional imaging and quantification of multineuronal olfactory responses in publication-title: Sci. Adv. doi: 10.1126/sciadv.ade1249 – ident: CR51 – volume: 314 start-page: 1 year: 1986 end-page: 340 ident: CR1 article-title: The structure of the nervous system of the nematode publication-title: Phil. Trans. R. Soc. B – volume: 274 start-page: 1724 year: 1996 end-page: 1726 ident: CR42 article-title: Chaos in neuronal networks with balanced excitatory and inhibitory activity publication-title: Science doi: 10.1126/science.274.5293.1724 – volume: 5 start-page: e19887 year: 2016 ident: CR54 article-title: Neuroendocrine modulation sustains the forward motor state publication-title: eLife doi: 10.7554/eLife.19887 – volume: 72 start-page: 231 year: 2011 end-page: 243 ident: CR43 article-title: How inhibition shapes cortical activity publication-title: Neuron doi: 10.1016/j.neuron.2011.09.027 – volume: 13 start-page: e1005517 year: 2017 ident: CR69 article-title: Automatically tracking neurons in a moving and deforming brain publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1005517 – volume: 571 start-page: 63 year: 2019 end-page: 71 ident: CR5 article-title: Whole-animal connectomes of both sexes publication-title: Nature doi: 10.1038/s41586-019-1352-7 – volume: 16 start-page: 22039 year: 2008 end-page: 22047 ident: CR71 article-title: Patterned two-photon illumination by spatiotemporal shaping of ultrashort pulses publication-title: Opt. Express doi: 10.1364/OE.16.022039 – volume: 35 start-page: 13917 year: 2015 end-page: 13926 ident: CR21 article-title: All-optical interrogation of neural circuits publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2916-15.2015 – volume: 6 start-page: e24666 year: 2011 ident: CR33 article-title: An image-free opto-mechanical system for creating virtual environments and imaging neuronal activity in freely moving publication-title: PLoS ONE doi: 10.1371/journal.pone.0024666 – volume: 49 start-page: 303 year: 2001 end-page: 313 ident: CR29 article-title: Serotonin modulates locomotory behavior and coordinates egg-laying and movement in publication-title: J. Neurobiol. doi: 10.1002/neu.10014 – volume: 248 start-page: 73 year: 1990 end-page: 76 ident: CR64 article-title: Two-photon laser scanning fluorescence microscopy publication-title: Science doi: 10.1126/science.2321027 – volume: 9 start-page: e56942 year: 2020 ident: CR36 article-title: Flexible motor sequence generation during stereotyped escape responses publication-title: eLife doi: 10.7554/eLife.56942 – volume: 182 start-page: 1372 year: 2020 end-page: 1376 ident: CR3 article-title: The mind of a mouse publication-title: Cell doi: 10.1016/j.cell.2020.08.010 – volume: 12 start-page: 140 year: 2015 end-page: 146 ident: CR20 article-title: Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo publication-title: Nat. Methods doi: 10.1038/nmeth.3217 – volume: 8 year: 2018 ident: CR70 article-title: Accurate and robust non-rigid point set registration using Student’s-t mixture model with prior probability modeling publication-title: Sci. Rep. doi: 10.1038/s41598-018-26288-6 – volume: 6 start-page: 891 year: 2009 end-page: 896 ident: CR18 article-title: Optical interrogation of neural circuits in publication-title: Nat. Methods doi: 10.1038/nmeth.1397 – volume: 57 start-page: 5 year: 2005 end-page: 7 ident: CR2 article-title: Imaging connectivity in the human cerebral cortex: the next frontier? publication-title: Ann. Neurol. doi: 10.1002/ana.20368 – volume: 16 start-page: e1007974 year: 2020 ident: CR37 article-title: Synaptic polarity and sign-balance prediction using gene expression data in the chemical synapse neuronal connectome network publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1007974 – volume: 184 start-page: 272–288 year: 2021 ident: CR27 article-title: NeuroPAL: a multicolor atlas for whole-brain neuronal identification in publication-title: Cell doi: 10.1016/j.cell.2020.12.012 – volume: 89 start-page: 052805 year: 2014 ident: CR47 article-title: Low-dimensional functionality of complex network dynamics: neurosensory integration in the connectome publication-title: Phys. Rev. E doi: 10.1103/PhysRevE.89.052805 – ident: CR57 – volume: 100 start-page: 9440 year: 2003 end-page: 9445 ident: CR40 article-title: Statistical significance for genomewide studies publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1530509100 – volume: 10 start-page: e66410 year: 2021 ident: CR58 article-title: Fast deep neural correspondence for tracking and identifying neurons in using semi-synthetic training publication-title: eLife doi: 10.7554/eLife.66410 – volume: 171 start-page: 1649–1662 year: 2017 ident: CR46 article-title: Neuromodulatory control of long-term behavioral patterns and individuality across development publication-title: Cell doi: 10.1016/j.cell.2017.10.041 – volume: 187 start-page: 229 year: 2010 end-page: 234 ident: CR32 article-title: Automated imaging of neuronal activity in freely behaving publication-title: J. Neurosci. Methods doi: 10.1016/j.jneumeth.2010.01.011 – volume: 14 start-page: 39 year: 1991 end-page: 57 ident: CR16 article-title: Modulation of neural networks for behavior publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.ne.14.030191.000351 – volume: 550 start-page: 519 year: 2017 end-page: 523 ident: CR10 article-title: Network control principles predict neuron function in the connectome publication-title: Nature doi: 10.1038/nature24056 – volume: 10 start-page: e66135 year: 2021 ident: CR68 article-title: Decoding locomotion from population neural activity in moving publication-title: eLife doi: 10.7554/eLife.66135 – volume: 72 start-page: 572 year: 2011 end-page: 586 ident: CR31 article-title: An imbalancing act: gap junctions reduce the backward motor circuit activity to bias for forward locomotion publication-title: Neuron doi: 10.1016/j.neuron.2011.09.005 – volume: 161 start-page: 215 year: 2015 end-page: 227 ident: CR45 article-title: Feedback from network states generates variability in a probabilistic olfactory circuit publication-title: Cell doi: 10.1016/j.cell.2015.02.018 – ident: CR66 – volume: 29 start-page: 25 year: 2014 end-page: 32 ident: CR11 article-title: Dual-transmitter neurons: functional implications of co-release and co-transmission publication-title: Curr. Opin. Neurobiol. doi: 10.1016/j.conb.2014.04.010 – volume: 5 start-page: 956 year: 1985 end-page: 964 ident: CR7 article-title: The neural circuit for touch sensitivity in publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.05-04-00956.1985 – volume: 163 start-page: 656 year: 2015 end-page: 669 ident: CR35 article-title: Global brain dynamics embed the motor command sequence of publication-title: Cell doi: 10.1016/j.cell.2015.09.034 – volume: 126 start-page: 118102 year: 2021 ident: CR55 article-title: Nonequilibrium Green’s functions for functional connectivity in the brain publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.126.118102 – volume: 10 start-page: 663 year: 2007 end-page: 668 ident: CR17 article-title: Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections publication-title: Nat. Neurosci. doi: 10.1038/nn1891 – volume: 113 start-page: E1074 year: 2016 end-page: E1081 ident: CR62 article-title: Whole-brain calcium imaging with cellular resolution in freely behaving publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1507110112 – volume: 596 start-page: 257 year: 2021 end-page: 261 ident: CR6 article-title: Connectomes across development reveal principles of brain maturation publication-title: Nature doi: 10.1038/s41586-021-03778-8 – volume: 8 start-page: e47889 year: 2019 ident: CR50 article-title: Single-cell transcriptomic evidence for dense intracortical neuropeptide networks publication-title: eLife doi: 10.7554/eLife.47889 – volume: 12 start-page: e1005283 year: 2016 ident: CR49 article-title: The multilayer connectome of Caenorhabditis elegans publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1005283 – volume: 184 start-page: 4329–4347 year: 2021 ident: CR38 article-title: Molecular topography of an entire nervous system publication-title: Cell doi: 10.1016/j.cell.2021.06.023 – volume: 102 start-page: 3184 year: 2005 end-page: 3191 ident: CR8 article-title: A circuit for navigation in publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0409009101 – volume: 11 start-page: 53 year: 2017 ident: CR9 article-title: Multistability and long-timescale transients encoded by network structure in a model of connectome dynamics publication-title: Front. Comput. Neurosci. doi: 10.3389/fncom.2017.00053 – volume: 113 start-page: E1082 year: 2016 end-page: 1088 ident: CR63 article-title: Pan-neuronal imaging in roaming publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1507109113 – ident: CR23 – volume: 159 start-page: 751 year: 2014 end-page: 765 ident: CR60 article-title: Encoding of both analog- and digital-like behavioral outputs by one interneuron publication-title: Cell doi: 10.1016/j.cell.2014.09.056 – volume: 108 start-page: 9667 year: 2011 end-page: 9672 ident: CR48 article-title: Transfer characteristics of a thermosensory synapse in Caenorhabditis elegans publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1106617108 – volume: 12 start-page: 433 year: 1994 end-page: 442 ident: CR13 article-title: Synaptic glutamate release by postnatal rat serotonergic neurons in microculture publication-title: Neuron doi: 10.1016/0896-6273(94)90283-6 – volume: 42 start-page: 113058 year: 2023 ident: CR52 article-title: System-wide mapping of neuropeptide–GPCR interactions in publication-title: Cell Rep. doi: 10.1016/j.celrep.2023.113058 – volume: 8 start-page: 41 year: 2008 end-page: 47 ident: CR39 article-title: The cys-loop ligand-gated ion channel gene superfamily of the nematode, publication-title: Invert. Neurosci. doi: 10.1007/s10158-008-0068-4 – volume: 106 start-page: 15025 year: 2009 end-page: 15030 ident: CR65 article-title: Two-photon excitation of channelrhodopsin-2 at saturation publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0907084106 – volume: 373 start-page: 20170374 year: 2018 ident: CR73 article-title: From head to tail: a neuromechanical model of forward locomotion in publication-title: Phil. Trans. R. Soc. B doi: 10.1098/rstb.2017.0374 – volume: 3 start-page: 167 year: 2012 ident: CR74 article-title: Neuropeptide GPCRs in publication-title: Front. Endocrinol. doi: 10.3389/fendo.2012.00167 – volume: 8 start-page: 2091 year: 2018 end-page: 2097 ident: CR56 article-title: Rapid integration of multi-copy transgenes using optogenetic mutagenesis in publication-title: G3 doi: 10.1534/g3.118.200158 – volume: 211 start-page: 419 year: 2019 end-page: 430 ident: CR61 article-title: A new tool for inducible gene expression in publication-title: Genetics doi: 10.1534/genetics.118.301705 – volume: 8 start-page: 28 year: 2014 ident: CR34 article-title: Simultaneous optogenetic manipulation and calcium imaging in freely moving publication-title: Front. Neural Circuits doi: 10.3389/fncir.2014.00028 – volume: 85 start-page: 804 year: 2015 end-page: 818 ident: CR24 article-title: Light and hydrogen peroxide inhibit feeding through gustatory receptor orthologs and pharyngeal neurons publication-title: Neuron doi: 10.1016/j.neuron.2014.12.061 – volume: 15 start-page: 657 year: 1987 end-page: 680 ident: CR72 article-title: A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability publication-title: J. Pharmacokinet. Biopharm. doi: 10.1007/BF01068419 – volume: 576 start-page: 121 year: 2019 end-page: 125 ident: CR15 article-title: Sensorimotor experience remaps visual input to a heading-direction network publication-title: Nature doi: 10.1038/s41586-019-1772-4 – volume: 17 start-page: 1816 year: 2014 end-page: 1824 ident: CR19 article-title: Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields publication-title: Nat. Neurosci. doi: 10.1038/nn.3866 – volume: 7 year: 2016 ident: CR14 article-title: Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement publication-title: Nat. Commun. doi: 10.1038/ncomms13697 – volume: 7 start-page: e37017 year: 2018 ident: CR22 article-title: Building a functional connectome of the central complex publication-title: eLife doi: 10.7554/eLife.37017 – volume: 27 start-page: 6150 year: 2007 end-page: 6162 ident: CR53 article-title: UNC-31 (CAPS) Is required for dense-core vesicle but not synaptic vesicle exocytosis in publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.1466-07.2007 – volume: 121–122 start-page: 86 year: 2017 end-page: 93 ident: CR59 article-title: Precision genome editing using CRISPR–Cas9 and linear repair templates in publication-title: Methods doi: 10.1016/j.ymeth.2017.03.023 – volume: 16 start-page: 4017 year: 1996 end-page: 4031 ident: CR30 article-title: A dynamic network simulation of the nematode tap withdrawal circuit: predictions concerning synaptic function using behavioral criteria publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-12-04017.1996 – volume: 32 start-page: 3443 year: 2022 end-page: 3459 ident: CR41 article-title: A set of hub neurons and non-local connectivity features support global brain dynamics in publication-title: Curr. Biol. doi: 10.1016/j.cub.2022.06.039 – volume: 261 start-page: 388 year: 1987 end-page: 404 ident: CR44 article-title: GABA immunoreactive neurons in rat visual cortex publication-title: J. Comp. Neurol. doi: 10.1002/cne.902610305 – volume: 211 start-page: 419 year: 2019 ident: 6683_CR61 publication-title: Genetics doi: 10.1534/genetics.118.301705 – volume: 16 start-page: 22039 year: 2008 ident: 6683_CR71 publication-title: Opt. Express doi: 10.1364/OE.16.022039 – volume: 8 start-page: 41 year: 2008 ident: 6683_CR39 publication-title: Invert. Neurosci. doi: 10.1007/s10158-008-0068-4 – volume: 113 start-page: E1074 year: 2016 ident: 6683_CR62 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1507110112 – volume: 571 start-page: 63 year: 2019 ident: 6683_CR5 publication-title: Nature doi: 10.1038/s41586-019-1352-7 – volume: 9 start-page: eade1249 year: 2023 ident: 6683_CR28 publication-title: Sci. Adv. doi: 10.1126/sciadv.ade1249 – volume: 89 start-page: 052805 year: 2014 ident: 6683_CR47 publication-title: Phys. Rev. E doi: 10.1103/PhysRevE.89.052805 – volume: 6 start-page: e24666 year: 2011 ident: 6683_CR33 publication-title: PLoS ONE doi: 10.1371/journal.pone.0024666 – volume: 12 start-page: 433 year: 1994 ident: 6683_CR13 publication-title: Neuron doi: 10.1016/0896-6273(94)90283-6 – volume: 106 start-page: 15025 year: 2009 ident: 6683_CR65 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0907084106 – volume: 10 start-page: e66135 year: 2021 ident: 6683_CR68 publication-title: eLife doi: 10.7554/eLife.66135 – volume: 187 start-page: 229 year: 2010 ident: 6683_CR32 publication-title: J. Neurosci. Methods doi: 10.1016/j.jneumeth.2010.01.011 – volume: 274 start-page: 1724 year: 1996 ident: 6683_CR42 publication-title: Science doi: 10.1126/science.274.5293.1724 – volume: 113 start-page: E1074 year: 2015 ident: 6683_CR67 publication-title: Proc. Natl Acad. Sci. USA – volume: 7 start-page: e37017 year: 2018 ident: 6683_CR22 publication-title: eLife doi: 10.7554/eLife.37017 – volume: 85 start-page: 804 year: 2015 ident: 6683_CR24 publication-title: Neuron doi: 10.1016/j.neuron.2014.12.061 – volume: 314 start-page: 1 year: 1986 ident: 6683_CR1 publication-title: Phil. Trans. R. Soc. B – volume: 5 start-page: e19887 year: 2016 ident: 6683_CR54 publication-title: eLife doi: 10.7554/eLife.19887 – volume: 248 start-page: 73 year: 1990 ident: 6683_CR64 publication-title: Science doi: 10.1126/science.2321027 – volume: 14 start-page: 39 year: 1991 ident: 6683_CR16 publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.ne.14.030191.000351 – volume: 261 start-page: 388 year: 1987 ident: 6683_CR44 publication-title: J. Comp. Neurol. doi: 10.1002/cne.902610305 – ident: 6683_CR57 doi: 10.1895/wormbook.1.108.1 – volume: 184 start-page: 272–288 year: 2021 ident: 6683_CR27 publication-title: Cell doi: 10.1016/j.cell.2020.12.012 – volume: 27 start-page: 6150 year: 2007 ident: 6683_CR53 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.1466-07.2007 – ident: 6683_CR4 doi: 10.1101/2020.08.21.260984 – volume: 49 start-page: 303 year: 2001 ident: 6683_CR29 publication-title: J. Neurobiol. doi: 10.1002/neu.10014 – volume: 171 start-page: 1649–1662 year: 2017 ident: 6683_CR46 publication-title: Cell doi: 10.1016/j.cell.2017.10.041 – ident: 6683_CR66 – ident: 6683_CR51 doi: 10.1101/2022.10.30.514396 – volume: 16 start-page: e1007974 year: 2020 ident: 6683_CR37 publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1007974 – volume: 184 start-page: 4329–4347 year: 2021 ident: 6683_CR38 publication-title: Cell doi: 10.1016/j.cell.2021.06.023 – volume: 596 start-page: 257 year: 2021 ident: 6683_CR6 publication-title: Nature doi: 10.1038/s41586-021-03778-8 – volume: 8 year: 2018 ident: 6683_CR70 publication-title: Sci. Rep. doi: 10.1038/s41598-018-26288-6 – volume: 11 start-page: 53 year: 2017 ident: 6683_CR9 publication-title: Front. Comput. Neurosci. doi: 10.3389/fncom.2017.00053 – volume: 8 start-page: e47889 year: 2019 ident: 6683_CR50 publication-title: eLife doi: 10.7554/eLife.47889 – volume: 15 start-page: 657 year: 1987 ident: 6683_CR72 publication-title: J. Pharmacokinet. Biopharm. doi: 10.1007/BF01068419 – volume: 72 start-page: 572 year: 2011 ident: 6683_CR31 publication-title: Neuron doi: 10.1016/j.neuron.2011.09.005 – volume: 6 start-page: 891 year: 2009 ident: 6683_CR18 publication-title: Nat. Methods doi: 10.1038/nmeth.1397 – volume: 8 start-page: 28 year: 2014 ident: 6683_CR34 publication-title: Front. Neural Circuits doi: 10.3389/fncir.2014.00028 – volume: 182 start-page: 1372 year: 2020 ident: 6683_CR3 publication-title: Cell doi: 10.1016/j.cell.2020.08.010 – volume: 35 start-page: 13917 year: 2015 ident: 6683_CR21 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2916-15.2015 – volume: 9 start-page: e56942 year: 2020 ident: 6683_CR36 publication-title: eLife doi: 10.7554/eLife.56942 – volume: 161 start-page: 215 year: 2015 ident: 6683_CR45 publication-title: Cell doi: 10.1016/j.cell.2015.02.018 – volume: 12 start-page: 140 year: 2015 ident: 6683_CR20 publication-title: Nat. Methods doi: 10.1038/nmeth.3217 – volume: 17 start-page: 1816 year: 2014 ident: 6683_CR19 publication-title: Nat. Neurosci. doi: 10.1038/nn.3866 – volume: 72 start-page: 231 year: 2011 ident: 6683_CR43 publication-title: Neuron doi: 10.1016/j.neuron.2011.09.027 – volume: 550 start-page: 519 year: 2017 ident: 6683_CR10 publication-title: Nature doi: 10.1038/nature24056 – volume: 163 start-page: 656 year: 2015 ident: 6683_CR35 publication-title: Cell doi: 10.1016/j.cell.2015.09.034 – volume: 499 start-page: 295 year: 2013 ident: 6683_CR26 publication-title: Nature doi: 10.1038/nature12354 – volume: 10 start-page: e66410 year: 2021 ident: 6683_CR58 publication-title: eLife doi: 10.7554/eLife.66410 – volume: 13 start-page: e1005517 year: 2017 ident: 6683_CR69 publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1005517 – volume: 12 start-page: 1394 year: 1992 ident: 6683_CR12 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.12-04-01394.1992 – volume: 29 start-page: 25 year: 2014 ident: 6683_CR11 publication-title: Curr. Opin. Neurobiol. doi: 10.1016/j.conb.2014.04.010 – volume: 576 start-page: 121 year: 2019 ident: 6683_CR15 publication-title: Nature doi: 10.1038/s41586-019-1772-4 – volume: 3 start-page: 167 year: 2012 ident: 6683_CR74 publication-title: Front. Endocrinol. doi: 10.3389/fendo.2012.00167 – volume: 16 start-page: 4017 year: 1996 ident: 6683_CR30 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-12-04017.1996 – volume: 108 start-page: 9667 year: 2011 ident: 6683_CR48 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1106617108 – ident: 6683_CR23 doi: 10.1101/2023.08.03.551820 – volume: 42 start-page: 113058 year: 2023 ident: 6683_CR52 publication-title: Cell Rep. doi: 10.1016/j.celrep.2023.113058 – volume: 32 start-page: 3443 year: 2022 ident: 6683_CR41 publication-title: Curr. Biol. doi: 10.1016/j.cub.2022.06.039 – volume: 159 start-page: 751 year: 2014 ident: 6683_CR60 publication-title: Cell doi: 10.1016/j.cell.2014.09.056 – volume: 121–122 start-page: 86 year: 2017 ident: 6683_CR59 publication-title: Methods doi: 10.1016/j.ymeth.2017.03.023 – volume: 113 start-page: E1082 year: 2016 ident: 6683_CR63 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1507109113 – volume: 8 start-page: 2091 year: 2018 ident: 6683_CR56 publication-title: G3 doi: 10.1534/g3.118.200158 – volume: 57 start-page: 5 year: 2005 ident: 6683_CR2 publication-title: Ann. Neurol. doi: 10.1002/ana.20368 – volume: 7 year: 2016 ident: 6683_CR14 publication-title: Nat. Commun. doi: 10.1038/ncomms13697 – volume: 12 start-page: e1005283 year: 2016 ident: 6683_CR49 publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1005283 – volume: 100 start-page: 9440 year: 2003 ident: 6683_CR40 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1530509100 – volume: 102 start-page: 3184 year: 2005 ident: 6683_CR8 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0409009101 – volume: 373 start-page: 20170374 year: 2018 ident: 6683_CR73 publication-title: Phil. Trans. R. Soc. B doi: 10.1098/rstb.2017.0374 – volume: 17 start-page: e0274226 year: 2022 ident: 6683_CR25 publication-title: PLoS ONE doi: 10.1371/journal.pone.0274226 – volume: 5 start-page: 956 year: 1985 ident: 6683_CR7 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.05-04-00956.1985 – volume: 126 start-page: 118102 year: 2021 ident: 6683_CR55 publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.126.118102 – volume: 10 start-page: 663 year: 2007 ident: 6683_CR17 publication-title: Nat. Neurosci. doi: 10.1038/nn1891
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Snippet	Establishing how neural function emerges from network properties is a fundamental problem in neuroscience 1 . Here, to better understand the relationship... Establishing how neural function emerges from network properties is a fundamental problem in neuroscience . Here, to better understand the relationship between... Establishing how neural function emerges from network properties is a fundamental problem in neuroscience1. Here, to better understand the relationship between...
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Title	Neural signal propagation atlas of Caenorhabditis elegans
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