Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast

Background There is limited knowledge about DCIS cellular composition and relationship with breast cancer events (BCE). Methods Immunofluorescence multiplexing (MxIF) was used to image and quantify 32 cellular biomarkers in FFPE DCIS tissue microarrays. Over 75,000 DCIS cells from 51 patients (media...

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Veröffentlicht in:	British journal of cancer Jg. 124; H. 6; S. 1150 - 1159
Hauptverfasser:	Badve, Sunil S., Cho, Sanghee, Gökmen-Polar, Yesim, Sui, Yunxia, Chadwick, Chrystal, McDonough, Elizabeth, Sood, Anup, Taylor, Marian, Zavodszky, Maria, Tan, Puay Hoon, Gerdes, Michael, Harris, Adrian L., Ginty, Fiona
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 16.03.2021 Nature Publishing Group
Schlagworte:	631/67/1347 692/53/2422 Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomarkers Biomarkers, Tumor - metabolism Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Breast Neoplasms - therapy Cancer Research Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - pathology Carcinoma, Ductal, Breast - therapy Carcinoma, Intraductal, Noninfiltrating - metabolism Carcinoma, Intraductal, Noninfiltrating - pathology Carcinoma, Intraductal, Noninfiltrating - therapy Cluster analysis Combined Modality Therapy Drug Resistance Epidemiology ErbB-2 protein Female Follow-Up Studies Humans Immunofluorescence Mastectomy - methods Middle Aged Molecular Medicine Oncology Prognosis Retrospective Studies Survival Rate
ISSN:	0007-0920, 1532-1827, 1532-1827
Online-Zugang:	Volltext
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