Socio-economic inequalities in cancer survival: how do they translate into Number of Life-Years Lost?

We aimed to investigate the impact of socio-economic inequalities in cancer survival in England on the Number of Life-Years Lost (NLYL) due to cancer. We analysed 1.2 million patients diagnosed with one of the 23 most common cancers (92.3% of all incident cancers in England) between 2010 and 2014. S...

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Bibliographic Details
Published in:British journal of cancer Vol. 126; no. 10; pp. 1490 - 1498
Main Authors: Exarchakou, Aimilia, Kipourou, Dimitra-Kleio, Belot, Aurélien, Rachet, Bernard
Format: Journal Article
Language:English
Published: England Nature Publishing Group 01.06.2022
Subjects:
Adult
Age
Cancer
Death
Diagnosis
England - epidemiology
Esophageal cancer
Humans
Infant
Lung cancer
Medical prognosis
Neoplasms - epidemiology
Pancreatic cancer
Prognosis
Socioeconomic Factors
Survival
England
United Kingdom > UK
ISSN:0007-0920, 1532-1827, 1532-1827
Online Access:Get full text
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Summary:We aimed to investigate the impact of socio-economic inequalities in cancer survival in England on the Number of Life-Years Lost (NLYL) due to cancer. We analysed 1.2 million patients diagnosed with one of the 23 most common cancers (92.3% of all incident cancers in England) between 2010 and 2014. Socio-economic deprivation of patients was based on the income domain of the English Index of Deprivation. We estimated the NLYL due to cancer within 3 years since diagnosis for each cancer and stratified by sex, age and deprivation, using a non-parametric approach. The relative survival framework enables us to disentangle death from cancer and death from other causes without the information on the cause of death. The largest socio-economic inequalities were seen mostly in adults <45 years with poor-prognosis cancers. In this age group, the most deprived patients with lung, pancreatic and oesophageal cancer lost up to 6 additional months within 3 years since diagnosis than the least deprived. For most moderate/good prognosis cancers, the socio-economic inequalities widened with age. More deprived patients and particularly the young with more lethal cancers, lose systematically more life-years than the less deprived. To reduce these inequalities, cancer policies should systematically encompass the inequities component.
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ISSN:0007-0920
1532-1827
1532-1827
DOI:10.1038/s41416-022-01720-x