Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

Abstract Despite the key role of the human ribosome in protein biosynthesis, little is known about the extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products. We recovered ribosomal DNA segments from a single human chromosome 21 using transformation-associated recombi...

Full description

Bibliographic Details

Published in:	Nucleic acids research Vol. 46; no. 13; pp. 6712 - 6725
Main Authors:	Kim, Jung-Hyun, Dilthey, Alexander T, Nagaraja, Ramaiah, Lee, Hee-Sheung, Koren, Sergey, Dudekula, Dawood, Wood III, William H, Piao, Yulan, Ogurtsov, Aleksey Y, Utani, Koichi, Noskov, Vladimir N, Shabalina, Svetlana A, Schlessinger, David, Phillippy, Adam M, Larionov, Vladimir
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 27.07.2018
Subjects:	Genomics
ISSN:	0305-1048, 1362-4962, 1362-4962
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!