Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia

Multiparametric flow cytometry is an alternative approach to the polymerase chain reaction method for evaluating minimal residual disease in treatment protocols for primary acute lymphoblastic leukemia. Given considerable differences between primary and relapsed acute lymphoblastic leukemia treatmen...

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Bibliographic Details
Published in:	Haematologica (Roma) Vol. 100; no. 7; pp. 935 - 944
Main Authors:	Karawajew, L., Dworzak, M., Ratei, R., Rhein, P., Gaipa, G., Buldini, B., Basso, G., Hrusak, O., Ludwig, W.-D., Henze, G., Seeger, K., von Stackelberg, A., Mejstrikova, E., Eckert, C.
Format:	Journal Article
Language:	English
Published:	Italy Ferrata Storti Foundation 01.07.2015
Subjects:	Antigens, CD - genetics Antigens, CD - immunology Antineoplastic Agents - therapeutic use B-Lymphocytes - drug effects B-Lymphocytes - immunology B-Lymphocytes - pathology Biomarkers, Tumor - genetics Biomarkers, Tumor - immunology Bone Marrow - drug effects Bone Marrow - immunology Bone Marrow - pathology Child, Preschool DNA Nucleotidylexotransferase - genetics DNA Nucleotidylexotransferase - immunology Flow Cytometry - methods Gene Expression Humans Immunophenotyping Infant Neoplasm, Residual Polymerase Chain Reaction Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - immunology Recurrence
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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