Propagating Wave of ERK Activation Orients Collective Cell Migration

The biophysical framework of collective cell migration has been extensively investigated in recent years; however, it remains elusive how chemical inputs from neighboring cells are integrated to coordinate the collective movement. Here, we provide evidence that propagation waves of extracellular sig...

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Veröffentlicht in:	Developmental cell Jg. 43; H. 3; S. 305
Hauptverfasser:	Aoki, Kazuhiro, Kondo, Yohei, Naoki, Honda, Hiratsuka, Toru, Itoh, Reina E, Matsuda, Michiyuki
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 06.11.2017
Schlagworte:	Actomyosin - metabolism Animals Cell Movement - physiology Dogs Enzyme Activation Epithelial Cells - cytology Kidney - metabolism MAP Kinase Signaling System - physiology Mitogen-Activated Protein Kinases - metabolism Phosphorylation Wound Healing - physiology myosin light chain simulation mathematical model FRET force collective cell migration ERK
ISSN:	1878-1551, 1878-1551
Online-Zugang:	Weitere Angaben
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