Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease

Intravascular neutrophils and platelets collaborate in maintaining host integrity, but their interaction can also trigger thrombotic complications. We report here that cooperation between neutrophil and platelet lineages extends to the earliest stages of platelet formation by megakaryocytes in the b...

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Bibliographic Details

Published in:	Immunity (Cambridge, Mass.) Vol. 55; no. 12; p. 2285
Main Authors:	Petzold, Tobias, Zhang, Zhe, Ballesteros, Iván, Saleh, Inas, Polzin, Amin, Thienel, Manuela, Liu, Lulu, Ul Ain, Qurrat, Ehreiser, Vincent, Weber, Christian, Kilani, Badr, Mertsch, Pontus, Götschke, Jeremias, Cremer, Sophie, Fu, Wenwen, Lorenz, Michael, Ishikawa-Ankerhold, Hellen, Raatz, Elisabeth, El-Nemr, Shaza, Görlach, Agnes, Marhuenda, Esther, Stark, Konstantin, Pircher, Joachim, Stegner, David, Gieger, Christian, Schmidt-Supprian, Marc, Gaertner, Florian, Almendros, Isaac, Kelm, Malte, Schulz, Christian, Hidalgo, Andrés, Massberg, Steffen
Format:	Journal Article
Language:	English
Published:	United States 13.12.2022
Subjects:	Blood Platelets - physiology Cardiovascular Diseases Humans Megakaryocytes Myocardial Infarction Neutrophils Thrombopoiesis Thrombosis thromboinflammation thrombosis neutrophils thrombopoiesis mechanotransduction bone marrow
ISSN:	1097-4180, 1097-4180
Online Access:	Get more information
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