Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?

Cryptosporidiosis has been a notifiable infection in Norway since 2012 and giardiasis since 1977. For both infections, there has been an increase in notified cases. We used a questionnaire to explore whether this may be associated with implementation of molecular diagnostic methods. We received resp...

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Veröffentlicht in:European journal of clinical microbiology & infectious diseases Jg. 41; H. 5; S. 835 - 839
Hauptverfasser: Campbell, Sophie M., Pettersen, Frank O., Brekke, Hanne, Hanevik, Kurt, Robertson, Lucy J.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2022
Springer Nature B.V
Schlagworte:
Algorithms
Biomedical and Life Sciences
Biomedicine
Brief Report
Cryptosporidiosis
Diagnostic systems
Feces
Giardiasis
Internal Medicine
Laboratories
Medical Microbiology
Parasites
Sensitivity
Cryptosporidiosis
Testing algorithm
Diagnostics
Norway
Giardiasis
Notifiable infection
ISSN:0934-9723, 1435-4373, 1435-4373
Online-Zugang:Volltext
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Zusammenfassung:Cryptosporidiosis has been a notifiable infection in Norway since 2012 and giardiasis since 1977. For both infections, there has been an increase in notified cases. We used a questionnaire to explore whether this may be associated with implementation of molecular diagnostic methods. We received responses from 14 of 16 laboratories, most of which had implemented molecular diagnostic methods for these parasites. Algorithms for testing had also been modified, and several laboratories now test more faecal samples than previously for both parasites. The increase in reported cases may reflect not only higher sensitivity of diagnostic methods, but also more sample testing.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0934-9723
1435-4373
1435-4373
DOI:10.1007/s10096-022-04426-3