Waveform Morphology as a Surrogate for ICP Monitoring: A Comparison Between an Invasive and a Noninvasive Method

Background Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study...

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Published in:	Neurocritical care Vol. 37; no. 1; pp. 219 - 227
Main Authors:	de Moraes, Fabiano Moulin, Rocha, Eva, Barros, Felipe Chaves Duarte, Freitas, Flávio Geraldo Rezende, Miranda, Maramelia, Valiente, Raul Alberto, de Andrade, João Brainer Clares, Neto, Feres Eduardo Aparecido Chaddad, Silva, Gisele Sampaio
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2022 Springer Nature B.V
Subjects:	Accuracy Brain Cerebrospinal fluid COVID-19 Critical Care Medicine Hemorrhage Intensive Intensive care Internal Medicine Intracranial pressure Medicine Medicine & Public Health Morphology Neurology Neurosurgery Original Work Patients Sensors Software Stroke Neurointensive care unit Brain trauma Intracranial pressure wave morphology Stroke Noninvasive intracranial pressure monitor
ISSN:	1541-6933, 1556-0961, 1556-0961
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Abstract	Background Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension. Methods We prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave ( P 2/ P 1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min. Results We studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P 2/ P 1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8–16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P 2/ P 1 ratio and moderate for TTP using categoric ( κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value ( P 2/ P 1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72–0.93] for the P 2/ P 1 ratio and 0.694 (95% CI 0.60–0.74) for TTP. Conclusions The new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension. Clinical trial registration Trial registration: NCT05121155.
AbstractList	Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension.BACKGROUNDAlthough the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension.We prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave (P2/P1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min.METHODSWe prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave (P2/P1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min.We studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P2/P1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8-16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P2/P1 ratio and moderate for TTP using categoric (κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value (P2/P1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72-0.93] for the P2/P1 ratio and 0.694 (95% CI 0.60-0.74) for TTP.RESULTSWe studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P2/P1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8-16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P2/P1 ratio and moderate for TTP using categoric (κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value (P2/P1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72-0.93] for the P2/P1 ratio and 0.694 (95% CI 0.60-0.74) for TTP.The new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension. Clinical trial registration Trial registration: NCT05121155.CONCLUSIONSThe new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension. Clinical trial registration Trial registration: NCT05121155. Background Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension. Methods We prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave ( P 2/ P 1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min. Results We studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P 2/ P 1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8–16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P 2/ P 1 ratio and moderate for TTP using categoric ( κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value ( P 2/ P 1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72–0.93] for the P 2/ P 1 ratio and 0.694 (95% CI 0.60–0.74) for TTP. Conclusions The new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension. Clinical trial registration Trial registration: NCT05121155. BackgroundAlthough the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension.MethodsWe prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave (P2/P1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min.ResultsWe studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P2/P1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8–16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P2/P1 ratio and moderate for TTP using categoric (κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value (P2/P1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72–0.93] for the P2/P1 ratio and 0.694 (95% CI 0.60–0.74) for TTP.ConclusionsThe new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension.Clinical trial registration Trial registration: NCT05121155. Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several limitations. Therefore, noninvasive alternatives to ICP (ICPni) measurement are of great interest. The main objective of this study was to compare the correlation and agreement of wave morphology between ICP (standard intraventricular ICP monitoring) and a new ICPni monitor in patients admitted with stroke. The second objective was to estimate the discrimination of the noninvasive method to detect intracranial hypertension. We prospectively collected data of adults admitted to an intensive care unit with subarachnoid hemorrhage, intracerebral hemorrhage, or ischemic stroke in whom an invasive ICP monitor was placed. Measurements were simultaneously collected from two parameters [time-to-peak (TTP) and the ratio regarding the second and first peak of the ICP wave (P2/P1 ratio)] of ICP and ICPni wave morphology monitors (Brain4care). Intracranial hypertension was defined as an invasively measured sustained ICP > 20 mm Hg for at least 5 min. We studied 18 patients (subarachnoid hemorrhage = 14; intracerebral hemorrhage = 3; ischemic stroke = 1) on 60 occasions with a median age of 52 ± 14.3 years. A total of 197,400 waves (2495 min) from both ICP (standard ICP monitoring) and the ICPni monitor were sliced into 1-min-long segments, and we determined TTP and the P2/P1 ratio from the mean pulse. The median invasively measured ICP was 13 (9.8-16.2) mm Hg, and intracranial hypertension was present on 18 occasions (30%). The correlation and agreement between invasive and noninvasive methods for wave morphology were strong for the P2/P1 ratio and moderate for TTP using categoric (κ agreement 88.1% and 71.3%, respectively) and continuous (intraclass correlation coefficient 0.831 and 0.584, respectively) measures. There was a moderate but significant correlation with the mean ICP value (P2/P1 ratio r = 0.427; TTP r = 0.353; p < 0.001 for all) between noninvasive and invasive techniques. The areas under the curve to estimate intracranial hypertension were 0.786 [95% confidence interval (CI) 0.72-0.93] for the P2/P1 ratio and 0.694 (95% CI 0.60-0.74) for TTP. The new ICPni wave morphology monitor showed a good agreement with the standard invasive method and an acceptable discriminatory power to detect intracranial hypertension. Clinical trial registration Trial registration: NCT05121155.
Author	de Andrade, João Brainer Clares Freitas, Flávio Geraldo Rezende Miranda, Maramelia Silva, Gisele Sampaio Neto, Feres Eduardo Aparecido Chaddad Valiente, Raul Alberto de Moraes, Fabiano Moulin Rocha, Eva Barros, Felipe Chaves Duarte
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BackLink	https://www.ncbi.nlm.nih.gov/pubmed/35332426$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1007/s00701-005-0537-z 10.1007/s12028-016-0361-8 10.1089/neu.2009.0951 10.1136/jnnp.42.8.687 10.1016/j.medengphy.2007.01.005 10.1007/s12028-015-0224-8 10.3390/s18020465 10.1007/s12028-014-0040-6 10.1007/978-3-7091-0956-4_21 10.1007/978-3-319-22533-3_18 10.1186/s13054-020-03105-z 10.1016/j.wneu.2020.03.028 10.3171/jns.1983.59.5.0817 10.1111/ane.12541 10.3171/2013.6.JNS121577 10.3171/2015.11.JNS151529 10.3390/brainsci11070874 10.1227/01.NEU.0000369519.35932.F2 10.4037/ajcc2008.17.6.545 10.1007/978-3-319-65798-1_16 10.1007/s00701-015-2672-5 10.1007/s12028-016-0258-6 10.1186/s13054-015-1137-9 10.1089/neu.2011.2018 10.1007/s00701-016-2932-z 10.1016/j.surneu.2003.12.007 10.1007/978-3-030-59436-7_28 10.1007/s00701-021-04834-y 10.1590/0004-282x-anp-2020-0300 10.1227/NEU.0b013e3182675b42 10.1227/00006123-198510000-00008 10.1007/s12028-012-9672-6 10.1109/TBME.2020.3036283 10.1227/NEU.0b013e318227e0e1
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Copyright	Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society 2022 2022. Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society. Copyright Springer Nature B.V. Aug 2022
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Keywords	Neurointensive care unit Brain trauma Intracranial pressure wave morphology Stroke Noninvasive intracranial pressure monitor
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License	2022. Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
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References	JY Fan (1477_CR14) 2008; 6 PK Eide (1477_CR20) 2008; 30 N De Riva (1477_CR31) 2012; 17 C Robba (1477_CR34) 2020; 24 FM de Moraes (1477_CR6) 2021; 79 L Vinciguerra (1477_CR7) 2017; 27 E Carrera (1477_CR24) 2010; 27 A Sonig (1477_CR9) 2020; 138 G Frigieri (1477_CR19) 2018; 126 D Teichmann (1477_CR22) 2021; 68 M Harary (1477_CR8) 2018; 18 LW Xy (1477_CR11) 2009; 8 1477_CR13 ER Cardoso (1477_CR27) 1983; 59 A Hall (1477_CR36) 2016; 158 S Brasil (1477_CR18) 2021; 11 L Zacchetti (1477_CR5) 2015; 19 I Gomes (1477_CR17) 2021; 131 R Helbok (1477_CR3) 2014; 21 PJ Pitlyk (1477_CR10) 1985; 17 D Cardim (1477_CR4) 2016; 25 CG Nucci (1477_CR21) 2016; 158 S Mascarenhas (1477_CR12) 2012; 114 CJJ Avezaat (1477_CR26) 1979; 42 G Portella (1477_CR23) 2005; 147 DJ Kim (1477_CR35) 2012; 29 PK Eide (1477_CR29) 2011; 69 PK Eide (1477_CR25) 2016; 125 A Kazimierska (1477_CR28) 2021; 163 HI Fried (1477_CR1) 2016; 24 J Bellner (1477_CR30) 2004; 62 VM Srinivasan (1477_CR2) 2014; 120 A Behrens (1477_CR32) 2010; 66 B Cabella (1477_CR15) 2016; 122 C Zweifel (1477_CR33) 2012; 71 M Kasprowicz (1477_CR16) 2016; 134
References_xml	– volume: 147 start-page: 707 issue: 7 year: 2005 ident: 1477_CR23 publication-title: Acta Neurochir (Wien) doi: 10.1007/s00701-005-0537-z – volume: 27 start-page: 122 issue: 1 year: 2017 ident: 1477_CR7 publication-title: Neurocrit Care doi: 10.1007/s12028-016-0361-8 – volume: 27 start-page: 317 issue: 2 year: 2010 ident: 1477_CR24 publication-title: J Neurotrauma doi: 10.1089/neu.2009.0951 – volume: 42 start-page: 687 issue: 8 year: 1979 ident: 1477_CR26 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.42.8.687 – volume: 30 start-page: 34 issue: 1 year: 2008 ident: 1477_CR20 publication-title: Med Eng Phys doi: 10.1016/j.medengphy.2007.01.005 – volume: 24 start-page: 61 issue: 1 year: 2016 ident: 1477_CR1 publication-title: Neurocrit Care doi: 10.1007/s12028-015-0224-8 – volume: 18 start-page: 3 issue: 2 year: 2018 ident: 1477_CR8 publication-title: Sensors (Switzerland) doi: 10.3390/s18020465 – volume: 21 start-page: 85 issue: 2 year: 2014 ident: 1477_CR3 publication-title: Neurocrit Care doi: 10.1007/s12028-014-0040-6 – volume: 8 start-page: 745 year: 2009 ident: 1477_CR11 publication-title: Afr J Biotechnol – volume: 114 start-page: 117 year: 2012 ident: 1477_CR12 publication-title: Acta Neurochir Suppl doi: 10.1007/978-3-7091-0956-4_21 – volume: 122 start-page: 93 year: 2016 ident: 1477_CR15 publication-title: Acta Neurochir Suppl doi: 10.1007/978-3-319-22533-3_18 – volume: 24 start-page: 1 issue: 1 year: 2020 ident: 1477_CR34 publication-title: Crit Care doi: 10.1186/s13054-020-03105-z – volume: 138 start-page: 491 year: 2020 ident: 1477_CR9 publication-title: World Neurosurg doi: 10.1016/j.wneu.2020.03.028 – volume: 59 start-page: 817 issue: 5 year: 1983 ident: 1477_CR27 publication-title: J Neurosurg doi: 10.3171/jns.1983.59.5.0817 – volume: 134 start-page: 168 issue: 3 year: 2016 ident: 1477_CR16 publication-title: Acta Neurol Scand doi: 10.1111/ane.12541 – volume: 120 start-page: 228 issue: 1 year: 2014 ident: 1477_CR2 publication-title: J Neurosurg doi: 10.3171/2013.6.JNS121577 – volume: 125 start-page: 1493 issue: 6 year: 2016 ident: 1477_CR25 publication-title: J Neurosurg doi: 10.3171/2015.11.JNS151529 – volume: 11 start-page: 874 year: 2021 ident: 1477_CR18 publication-title: Brain Sciences doi: 10.3390/brainsci11070874 – volume: 66 start-page: 1050 issue: 6 year: 2010 ident: 1477_CR32 publication-title: Neurosurgery doi: 10.1227/01.NEU.0000369519.35932.F2 – volume: 6 start-page: 545 year: 2008 ident: 1477_CR14 publication-title: Am J Crit Care doi: 10.4037/ajcc2008.17.6.545 – volume: 126 start-page: 75 year: 2018 ident: 1477_CR19 publication-title: Acta Neurochir Suppl doi: 10.1007/978-3-319-65798-1_16 – volume: 158 start-page: 581 issue: 3 year: 2016 ident: 1477_CR21 publication-title: Acta Neurochir (Wien) doi: 10.1007/s00701-015-2672-5 – volume: 25 start-page: 473 issue: 3 year: 2016 ident: 1477_CR4 publication-title: Neurocrit Care doi: 10.1007/s12028-016-0258-6 – volume: 19 start-page: 1 issue: 1 year: 2015 ident: 1477_CR5 publication-title: Crit Care doi: 10.1186/s13054-015-1137-9 – volume: 29 start-page: 1354 issue: 7 year: 2012 ident: 1477_CR35 publication-title: J Neurotrauma doi: 10.1089/neu.2011.2018 – volume: 158 start-page: 1997 issue: 10 year: 2016 ident: 1477_CR36 publication-title: Acta Neurochir (Wien) doi: 10.1007/s00701-016-2932-z – ident: 1477_CR13 – volume: 62 start-page: 45 year: 2004 ident: 1477_CR30 publication-title: Surg Neurol doi: 10.1016/j.surneu.2003.12.007 – volume: 131 start-page: 135 year: 2021 ident: 1477_CR17 publication-title: Acta Neurochir Suppl doi: 10.1007/978-3-030-59436-7_28 – volume: 163 start-page: 1979 year: 2021 ident: 1477_CR28 publication-title: Acta Neurochir (Wien) doi: 10.1007/s00701-021-04834-y – volume: 79 start-page: 437 issue: 5 year: 2021 ident: 1477_CR6 publication-title: Arq Neuropsiquiatr doi: 10.1590/0004-282x-anp-2020-0300 – volume: 71 start-page: 853 issue: 4 year: 2012 ident: 1477_CR33 publication-title: Neurosurgery doi: 10.1227/NEU.0b013e3182675b42 – volume: 17 start-page: 581 year: 1985 ident: 1477_CR10 publication-title: Neurosurgery doi: 10.1227/00006123-198510000-00008 – volume: 17 start-page: 58 issue: 1 year: 2012 ident: 1477_CR31 publication-title: Neurocrit Care doi: 10.1007/s12028-012-9672-6 – volume: 68 start-page: 1646 issue: 5 year: 2021 ident: 1477_CR22 publication-title: IEEE Trans Biomed Eng doi: 10.1109/TBME.2020.3036283 – volume: 69 start-page: 1105 issue: 5 year: 2011 ident: 1477_CR29 publication-title: Neurosurgery doi: 10.1227/NEU.0b013e318227e0e1
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Snippet	Background Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has... Although the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has several... BackgroundAlthough the placement of an intraventricular catheter remains the gold standard technique for measuring intracranial pressure (ICP), the method has...
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SubjectTerms	Accuracy Brain Cerebrospinal fluid COVID-19 Critical Care Medicine Hemorrhage Intensive Intensive care Internal Medicine Intracranial pressure Medicine Medicine & Public Health Morphology Neurology Neurosurgery Original Work Patients Sensors Software Stroke
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Title	Waveform Morphology as a Surrogate for ICP Monitoring: A Comparison Between an Invasive and a Noninvasive Method
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