Relation Between the Number of Peaks and the Number of Reciprocal Sign Epistatic Interactions

Empirical essays of fitness landscapes suggest that they may be rugged, that is having multiple fitness peaks. Such fitness landscapes, those that have multiple peaks, necessarily have special local structures, called reciprocal sign epistasis (Poelwijk et al. in J Theor Biol 272:141–144, 2011). Her...

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Bibliographic Details
Published in:	Bulletin of mathematical biology Vol. 84; no. 8; p. 74
Main Authors:	Saona, Raimundo, Kondrashov, Fyodor A., Khudiakova, Ksenia A.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2022 Springer Nature B.V
Subjects:	Cell Biology Epistasis Epistasis, Genetic Fitness Genetic Fitness Life Sciences Mathematical and Computational Biology Mathematical Concepts Mathematics Mathematics and Statistics Models, Biological Models, Genetic Mutation Original Original Article Morse theory Fitness landscapes Reciprocal sign epistasis Multiple peaks
ISSN:	0092-8240, 1522-9602, 1522-9602
Online Access:	Get full text
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