An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID)
Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter...
Gespeichert in:
| Veröffentlicht in: | Neurological sciences Jg. 41; H. 6; S. 1355 - 1359 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Cham
Springer International Publishing
01.06.2020
Springer Nature B.V |
| Schlagworte: | |
| ISSN: | 1590-1874, 1590-3478, 1590-3478 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter retrospective-prospective observational study promoted by the Italian Society of Neurology (SIN), involving the Italian Neurological Departments, who will consecutively recruit patients with neurological symptoms and/or signs, occurred at the onset or as a complication of COVID-19. Hospitalized patients will be recruited either in neurological wards or in COVID wards; in the latter cases, they will be referred from other specialists to participant neurologists. Outpatients with clinical signs of COVID and neurological manifestations will be also referred to participating neurologists from primary care physicians. A comprehensive data collection, in the form of electronic case report form (eCRF), will register all possible neurological manifestations involving central nervous systems, peripheral nerves, and muscles, together with clinical, laboratory (including cerebrospinal fluid, if available), imaging, neurological, neurophysiological, and neuropsychological data. A follow-up at hospital discharge (in hospitalized patients), and for all patients after 3 and 6 months, is also planned. We believe that this study may help to intercept the full spectrum of neurological manifestations of COVID-19 and, given the large diffusion at national level, can provide a large cohort of patients available for future more focused investigations. Similar observational studies might also be proposed at international level to better define the neurological involvement of COVID-19. |
|---|---|
| AbstractList | Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter retrospective-prospective observational study promoted by the Italian Society of Neurology (SIN), involving the Italian Neurological Departments, who will consecutively recruit patients with neurological symptoms and/or signs, occurred at the onset or as a complication of COVID-19. Hospitalized patients will be recruited either in neurological wards or in COVID wards; in the latter cases, they will be referred from other specialists to participant neurologists. Outpatients with clinical signs of COVID and neurological manifestations will be also referred to participating neurologists from primary care physicians. A comprehensive data collection, in the form of electronic case report form (eCRF), will register all possible neurological manifestations involving central nervous systems, peripheral nerves, and muscles, together with clinical, laboratory (including cerebrospinal fluid, if available), imaging, neurological, neurophysiological, and neuropsychological data. A follow-up at hospital discharge (in hospitalized patients), and for all patients after 3 and 6 months, is also planned. We believe that this study may help to intercept the full spectrum of neurological manifestations of COVID-19 and, given the large diffusion at national level, can provide a large cohort of patients available for future more focused investigations. Similar observational studies might also be proposed at international level to better define the neurological involvement of COVID-19.Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter retrospective-prospective observational study promoted by the Italian Society of Neurology (SIN), involving the Italian Neurological Departments, who will consecutively recruit patients with neurological symptoms and/or signs, occurred at the onset or as a complication of COVID-19. Hospitalized patients will be recruited either in neurological wards or in COVID wards; in the latter cases, they will be referred from other specialists to participant neurologists. Outpatients with clinical signs of COVID and neurological manifestations will be also referred to participating neurologists from primary care physicians. A comprehensive data collection, in the form of electronic case report form (eCRF), will register all possible neurological manifestations involving central nervous systems, peripheral nerves, and muscles, together with clinical, laboratory (including cerebrospinal fluid, if available), imaging, neurological, neurophysiological, and neuropsychological data. A follow-up at hospital discharge (in hospitalized patients), and for all patients after 3 and 6 months, is also planned. We believe that this study may help to intercept the full spectrum of neurological manifestations of COVID-19 and, given the large diffusion at national level, can provide a large cohort of patients available for future more focused investigations. Similar observational studies might also be proposed at international level to better define the neurological involvement of COVID-19. Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter retrospective-prospective observational study promoted by the Italian Society of Neurology (SIN), involving the Italian Neurological Departments, who will consecutively recruit patients with neurological symptoms and/or signs, occurred at the onset or as a complication of COVID-19. Hospitalized patients will be recruited either in neurological wards or in COVID wards; in the latter cases, they will be referred from other specialists to participant neurologists. Outpatients with clinical signs of COVID and neurological manifestations will be also referred to participating neurologists from primary care physicians. A comprehensive data collection, in the form of electronic case report form (eCRF), will register all possible neurological manifestations involving central nervous systems, peripheral nerves, and muscles, together with clinical, laboratory (including cerebrospinal fluid, if available), imaging, neurological, neurophysiological, and neuropsychological data. A follow-up at hospital discharge (in hospitalized patients), and for all patients after 3 and 6 months, is also planned. We believe that this study may help to intercept the full spectrum of neurological manifestations of COVID-19 and, given the large diffusion at national level, can provide a large cohort of patients available for future more focused investigations. Similar observational studies might also be proposed at international level to better define the neurological involvement of COVID-19. |
| Author | Tedeschi, Gioacchino Monaco, Salvatore Priori, Alberto Galimberti, Stefania Agostoni, Elio Silani, Vincenzo Ferrarese, Carlo Padovani, Alessandro |
| Author_xml | – sequence: 1 givenname: Carlo orcidid: 0000-0002-7499-6600 surname: Ferrarese fullname: Ferrarese, Carlo email: carlo.ferrarese@unimib.it organization: Department of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca and San Gerardo Hospital – sequence: 2 givenname: Vincenzo surname: Silani fullname: Silani, Vincenzo organization: Istituto Auxologico Italiano, IRCCS, Department of Neurology and Laboratory of Neuroscience - Department of Pathophysiology and Transplantation, “Dino Ferrari” Center, Università degli Studi di Milano – sequence: 3 givenname: Alberto surname: Priori fullname: Priori, Alberto organization: Clinica Neurologica III, “Centro Aldo Ravelli” per le Terapie Neurologiche Sperimentali, Dipartimento di Scienze della Salute, Polo Universitario San Paolo, Università degli Studi di Milano – sequence: 4 givenname: Stefania surname: Galimberti fullname: Galimberti, Stefania organization: Bicocca Bioinformatics Biostatistics and Bioimaging Centre, Department of Medicine and Surgery, University of Milano – Bicocca – sequence: 5 givenname: Elio surname: Agostoni fullname: Agostoni, Elio organization: S.C. Neurologia e Stroke Unit ASST Grande Ospedale Metropolitano Niguarda – sequence: 6 givenname: Salvatore surname: Monaco fullname: Monaco, Salvatore organization: Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona – sequence: 7 givenname: Alessandro surname: Padovani fullname: Padovani, Alessandro organization: Department of Neurology, ASST Spedali Civili and University of Brescia – sequence: 8 givenname: Gioacchino surname: Tedeschi fullname: Tedeschi, Gioacchino organization: Department of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli” |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32430621$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kstu1DAUhi1URC_wAiyQJTZlkfY4tnPZIFXTAiNVHQlRtpbjORlcJfZgJyNV4uHxTKYtdNGNr9__69yOyYHzDgl5z-CMAZTncbvmGeSQgRASMvaKHDFZQ8ZFWR3sz6wqxSE5jvEOAJhg_A055LngUOTsiPy5cHQ-6M5qR_uxG6xBN2CgAYfg4xrNYDeYrZ_O1DcRw0YP1jvd0TiMy3vqHXU4Bt_5lTXptdfOthiHHRWpb-ls8XN-mbGant5c3X5f7K6f3pLXre4ivtvvJ-T2y9WP2bfsevF1Pru4zowoxZA1DGFpcsZbxtAYgAK0kSBrww1nRdE0BUcmy7pKqWKNgkHFJUcUhWiXsuAn5PPkux6bHpfbFIPu1DrYXod75bVV__84-0ut_EaVOZeSV8ngdG8Q_O8xJaZ6Gw12nXbox6hyAZKDqEEk9OMz9M6PIZVqR9U1Y7XME_Xh34geQ3loTAKqCTCp9DFgq4ydypkCtJ1ioLbdV9MMqDQDajcDaivNn0kf3F8U8UkUE-xWGJ7CfkH1F1ZFw-I |
| CitedBy_id | crossref_primary_10_26633_RPSP_2022_108 crossref_primary_10_1111_eci_13311 crossref_primary_10_1016_j_bbih_2021_100251 crossref_primary_10_1017_SJP_2021_40 crossref_primary_10_1016_j_jaclp_2022_01_003 crossref_primary_10_1016_j_arr_2020_101205 crossref_primary_10_1007_s12028_021_01192_6 crossref_primary_10_3390_medicina59030501 crossref_primary_10_1177_1759091420954960 crossref_primary_10_3389_fpsyg_2022_908363 crossref_primary_10_1371_journal_pone_0309102 crossref_primary_10_1016_j_acra_2024_03_018 crossref_primary_10_3233_JAD_200891 crossref_primary_10_1007_s00415_021_10517_6 crossref_primary_10_3390_brainsci13040528 crossref_primary_10_29262_ram_v67i4_828 crossref_primary_10_1016_j_jns_2021_117438 crossref_primary_10_3390_brainsci12010074 crossref_primary_10_7759_cureus_13475 crossref_primary_10_1038_s41598_023_40534_6 crossref_primary_10_1002_jmv_28240 crossref_primary_10_1007_s10072_021_05653_w crossref_primary_10_3389_fcimb_2022_998748 crossref_primary_10_1016_j_jns_2022_120355 crossref_primary_10_1155_2020_8844280 crossref_primary_10_3389_fneur_2020_00845 crossref_primary_10_1016_j_seizure_2021_01_009 crossref_primary_10_1016_j_amjms_2021_01_001 crossref_primary_10_1016_j_coph_2021_12_008 crossref_primary_10_1016_j_genhosppsych_2022_07_013 crossref_primary_10_1212_CPJ_0000000000001031 crossref_primary_10_3390_brainsci11020235 crossref_primary_10_1212_WNL_0000000000207534 crossref_primary_10_1136_bmjopen_2020_040944 crossref_primary_10_1016_j_clinph_2023_04_010 |
| Cites_doi | 10.1373/clinchem.2003.025437 10.1007/s11427-020-1690-y 10.3201/eid1002.030638 10.1002/jmv.25728 10.1007/s10072-020-04447-w 10.1016/j.bbi.2020.03.031 10.1111/cns.13372 10.1001/jama.2020.1585 10.1093/cid/ciaa330 10.1212/NXI.0000000000000741 10.1056/NEJMc2008597 10.3390/v12010014 10.1001/jamaneurol.2020.1127 |
| ContentType | Journal Article |
| Copyright | Fondazione Società Italiana di Neurologia 2020 Fondazione Società Italiana di Neurologia 2020. |
| Copyright_xml | – notice: Fondazione Società Italiana di Neurologia 2020 – notice: Fondazione Società Italiana di Neurologia 2020. |
| CorporateAuthor | on behalf of Italian Society of Neurology (SIN) Italian Society of Neurology (SIN) |
| CorporateAuthor_xml | – name: on behalf of Italian Society of Neurology (SIN) – name: Italian Society of Neurology (SIN) |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7TK 7X7 7XB 88E 88G 8AO 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ K9- K9. M0R M0S M1P M2M PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 5PM |
| DOI | 10.1007/s10072-020-04450-1 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Neurosciences Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials - QC ProQuest Central ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Consumer Health Database ProQuest Health & Medical Complete (Alumni) Consumer Health Database ProQuest Health & Medical Collection Medical Database Psychology Database Proquest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Family Health (Alumni Edition) ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest Family Health ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic ProQuest One Psychology MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1590-3478 |
| EndPage | 1359 |
| ExternalDocumentID | PMC7235538 32430621 10_1007_s10072_020_04450_1 |
| Genre | Multicenter Study Clinical Trial Journal Article Observational Study |
| GeographicLocations | Italy |
| GeographicLocations_xml | – name: Italy |
| GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C .86 .VR 06C 06D 0R~ 0VY 123 199 1N0 2.D 203 29N 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3V. 4.4 406 408 409 40D 40E 53G 5VS 67Z 6NX 78A 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAWTL AAYIU AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDBF ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABIVO ABJNI ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACSNA ACUDM ACUHS ACZOJ ADBBV ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADPHR ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFEXP AFKRA AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AOCGG ARMRJ AXYYD AZFZN AZQEC B-. B0M BA0 BDATZ BENPR BGNMA BKNYI BPHCQ BSONS BVXVI CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 DWQXO EAD EAP EAS EBC EBD EBLON EBS EBX ECV EHN EIOEI EJD EMB EMK EMOBN EN4 ENC ENX EPAXT EPL EPS EPT ESBYG ESX F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 GQ8 GRRUI GXS H13 HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ IMOTQ IWAJR IXC IXD IXE IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ K9- KDC KOV KPH LAS LLZTM M0R M1P M2M M4Y MA- N2Q N9A NB0 NDZJH NPVJJ NQJWS NU0 O93 O9G O9I O9J OAM OVD P19 P2P P9S PF0 PQQKQ PROAC PSQYO PSYQQ PT4 PT5 Q2X QOR QOS Q~Q R89 R9I RIG ROL RPX RRX RSV S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TEORI TSG TSK TSV TT1 TUC TUS U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 YLTOR Z45 Z7U Z82 Z83 Z87 Z8O Z8V Z91 ZMTXR ZOVNA ~8M ~A9 AAPKM AAYXX ABBRH ABDBE ABFSG ABRTQ ACSTC ADHKG AEZWR AFDZB AFFHD AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT PJZUB PPXIY CGR CUY CVF ECM EIF NPM 7TK 7XB 8FK K9. PKEHL PQEST PQUKI PRINS Q9U 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c474t-b1e0dc213f11ecc0060ac5059c3c3166bb63e15798874e9e4108353ee464fd563 |
| IEDL.DBID | RSV |
| ISICitedReferencesCount | 41 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000534203700003&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1590-1874 1590-3478 |
| IngestDate | Tue Nov 04 02:00:11 EST 2025 Fri Sep 05 11:54:57 EDT 2025 Tue Nov 04 23:16:54 EST 2025 Mon Jul 21 06:02:22 EDT 2025 Sat Nov 29 01:47:23 EST 2025 Tue Nov 18 22:12:07 EST 2025 Fri Feb 21 02:36:58 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | COVID-19 Neurological manifestations Observational study NEUROCOVID |
| Language | English |
| License | This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c474t-b1e0dc213f11ecc0060ac5059c3c3166bb63e15798874e9e4108353ee464fd563 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3 |
| ORCID | 0000-0002-7499-6600 |
| OpenAccessLink | http://dx.doi.org/10.1007/s10072-020-04450-1 |
| PMID | 32430621 |
| PQID | 2409911952 |
| PQPubID | 27321 |
| PageCount | 5 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7235538 proquest_miscellaneous_2405304904 proquest_journals_2409911952 pubmed_primary_32430621 crossref_citationtrail_10_1007_s10072_020_04450_1 crossref_primary_10_1007_s10072_020_04450_1 springer_journals_10_1007_s10072_020_04450_1 |
| PublicationCentury | 2000 |
| PublicationDate | 2020-06-01 |
| PublicationDateYYYYMMDD | 2020-06-01 |
| PublicationDate_xml | – month: 06 year: 2020 text: 2020-06-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Cham |
| PublicationPlace_xml | – name: Cham – name: Italy – name: Milano |
| PublicationTitle | Neurological sciences |
| PublicationTitleAbbrev | Neurol Sci |
| PublicationTitleAlternate | Neurol Sci |
| PublicationYear | 2020 |
| Publisher | Springer International Publishing Springer Nature B.V |
| Publisher_xml | – name: Springer International Publishing – name: Springer Nature B.V |
| References | Calcagno N, Colombo E, Maranzano A, Pasquini J, Keller Sarmiento IJ, Trogu F, Silani V (2020) Rising evidence for neurological involvement in COVID-19 pandemic. Neurol Sci. In press doi: https://doi.org/10.1007/s10072-020-04447-w Baig AM (2020) Neurological manifestations in COVID-19 caused by SARS-CoV-2. CNS Neurosci Ther 26(5):499-501. doi: https://doi.org/10.1111/cns.13372 LauKKYuWCChuCMLauSTShengBYuenKYPossible central nervous system infection by SARS coronavirusEmerg Infect Dis.200410234234410.3201/eid1002.030638 Alberti P, Beretta S, Piatti M, Karantzoulis A, Piatti ML, Santoro P, Viiganò M, Giovannelli G, Pirro F, Montisano DA, Appollonio I, Ferrarese C (2020) Guillain-Barré syndrome related to COVID-19 infection, Neurology. Neuroimmunol Neuroinflamm 7(4)e741 Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B (2020) Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol doi: https://doi.org/10.1001/jamaneurol.2020.1127 Giacomelli A, Pezzati L, Conti F, Bernacchia D, Siano M, Oreni L, Rusconi S, Gervasoni C, Ridolfo AL, Rizzardini G, Antinori S, Galli M (2020) Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study. Clin Infect Dis pii: ciaa330. doi: https://doi.org/10.1093/cid/ciaa330 Li YC, Bai WZ, Hashikawa T (2020) The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol doi: https://doi.org/10.1002/jmv.25728 FilatovASharmaPHindiFEspinosaPSNeurological complications of coronavirus disease (COVID-19): encephalopathyCureus2020123323283647170017 Desforges M, Le Coupanec A, Dubeau P, Bourgouin A, Lajoie L, Dubé M, Talbot PJ (2019) Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? Viruses 12(1) pii: E14. doi: https://doi.org/10.3390/v12010014 Li Z, Huang Y, Guo X (2020) The brain, another potential target organ, needs early protection from SARS-CoV-2 neuroinvasion. Sci China Life Sci 63(5):771-773. doi: https://doi.org/10.1007/s11427-020-1690-y HungECChimSSChanPKTongYKNgEKChiuRWLeungCBSungJJTamJSLoYMDetection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndromeClin Chem.20034912210821091:CAS:528:DC%2BD3sXpt1yntbw%3D10.1373/clinchem.2003.025437 Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z (2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA doi: https://doi.org/10.1001/jama.2020.1585 Wu Y, Xu X, Chen Z, Duan J, Hashimoto K, Yang L, Liu C, Yang C (2020) Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun pii: S0889-1591(20)30357-3. doi: https://doi.org/10.1016/j.bbi.2020.03.031 Helms J, Kremer S, Merdji H, Clere-Jehl R, Schenck M, Kummerlen C, Collange O, Boulay C, Fafi-Kremer S, Ohana M, Anheim M, Meziani F (2020) Neurologic features in severe SARS-CoV-2 infection. N Engl J Med doi: https://doi.org/10.1056/NEJMc2008597 4450_CR5 4450_CR6 4450_CR3 4450_CR10 4450_CR4 4450_CR11 4450_CR12 4450_CR13 4450_CR7 4450_CR14 A Filatov (4450_CR2) 2020; 12 KK Lau (4450_CR9) 2004; 10 EC Hung (4450_CR8) 2003; 49 4450_CR1 |
| References_xml | – reference: LauKKYuWCChuCMLauSTShengBYuenKYPossible central nervous system infection by SARS coronavirusEmerg Infect Dis.200410234234410.3201/eid1002.030638 – reference: Giacomelli A, Pezzati L, Conti F, Bernacchia D, Siano M, Oreni L, Rusconi S, Gervasoni C, Ridolfo AL, Rizzardini G, Antinori S, Galli M (2020) Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study. Clin Infect Dis pii: ciaa330. doi: https://doi.org/10.1093/cid/ciaa330 – reference: Li YC, Bai WZ, Hashikawa T (2020) The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol doi: https://doi.org/10.1002/jmv.25728 – reference: Wu Y, Xu X, Chen Z, Duan J, Hashimoto K, Yang L, Liu C, Yang C (2020) Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun pii: S0889-1591(20)30357-3. doi: https://doi.org/10.1016/j.bbi.2020.03.031 – reference: HungECChimSSChanPKTongYKNgEKChiuRWLeungCBSungJJTamJSLoYMDetection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndromeClin Chem.20034912210821091:CAS:528:DC%2BD3sXpt1yntbw%3D10.1373/clinchem.2003.025437 – reference: Baig AM (2020) Neurological manifestations in COVID-19 caused by SARS-CoV-2. CNS Neurosci Ther 26(5):499-501. doi: https://doi.org/10.1111/cns.13372 – reference: Li Z, Huang Y, Guo X (2020) The brain, another potential target organ, needs early protection from SARS-CoV-2 neuroinvasion. Sci China Life Sci 63(5):771-773. doi: https://doi.org/10.1007/s11427-020-1690-y – reference: Helms J, Kremer S, Merdji H, Clere-Jehl R, Schenck M, Kummerlen C, Collange O, Boulay C, Fafi-Kremer S, Ohana M, Anheim M, Meziani F (2020) Neurologic features in severe SARS-CoV-2 infection. N Engl J Med doi: https://doi.org/10.1056/NEJMc2008597 – reference: Alberti P, Beretta S, Piatti M, Karantzoulis A, Piatti ML, Santoro P, Viiganò M, Giovannelli G, Pirro F, Montisano DA, Appollonio I, Ferrarese C (2020) Guillain-Barré syndrome related to COVID-19 infection, Neurology. Neuroimmunol Neuroinflamm 7(4)e741 – reference: FilatovASharmaPHindiFEspinosaPSNeurological complications of coronavirus disease (COVID-19): encephalopathyCureus2020123323283647170017 – reference: Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z (2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA doi: https://doi.org/10.1001/jama.2020.1585 – reference: Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B (2020) Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol doi: https://doi.org/10.1001/jamaneurol.2020.1127 – reference: Calcagno N, Colombo E, Maranzano A, Pasquini J, Keller Sarmiento IJ, Trogu F, Silani V (2020) Rising evidence for neurological involvement in COVID-19 pandemic. Neurol Sci. In press doi: https://doi.org/10.1007/s10072-020-04447-w – reference: Desforges M, Le Coupanec A, Dubeau P, Bourgouin A, Lajoie L, Dubé M, Talbot PJ (2019) Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? Viruses 12(1) pii: E14. doi: https://doi.org/10.3390/v12010014 – volume: 49 start-page: 2108 issue: 12 year: 2003 ident: 4450_CR8 publication-title: Clin Chem. doi: 10.1373/clinchem.2003.025437 – ident: 4450_CR6 doi: 10.1007/s11427-020-1690-y – volume: 10 start-page: 342 issue: 2 year: 2004 ident: 4450_CR9 publication-title: Emerg Infect Dis. doi: 10.3201/eid1002.030638 – ident: 4450_CR12 doi: 10.1002/jmv.25728 – ident: 4450_CR14 doi: 10.1007/s10072-020-04447-w – ident: 4450_CR5 doi: 10.1016/j.bbi.2020.03.031 – ident: 4450_CR11 doi: 10.1111/cns.13372 – ident: 4450_CR13 doi: 10.1001/jama.2020.1585 – ident: 4450_CR3 doi: 10.1093/cid/ciaa330 – ident: 4450_CR1 doi: 10.1212/NXI.0000000000000741 – volume: 12 issue: 3 year: 2020 ident: 4450_CR2 publication-title: Cureus – ident: 4450_CR7 doi: 10.1056/NEJMc2008597 – ident: 4450_CR10 doi: 10.3390/v12010014 – ident: 4450_CR4 doi: 10.1001/jamaneurol.2020.1127 |
| SSID | ssj0001413 |
| Score | 2.4405322 |
| Snippet | Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1355 |
| SubjectTerms | Betacoronavirus Case reports Cerebrospinal fluid Coronavirus Infections - diagnosis Coronavirus Infections - epidemiology Coronavirus Infections - therapy Coronaviruses COVID-19 Data collection Humans Italy - epidemiology Medicine Medicine & Public Health Muscles Nervous System Diseases - diagnosis Nervous System Diseases - epidemiology Nervous System Diseases - therapy Neurology Neuroradiology Neurosciences Neurosurgery Observational studies Pandemics Patients Peripheral nerves Pneumonia, Viral - diagnosis Pneumonia, Viral - epidemiology Pneumonia, Viral - therapy Primary care Prospective Studies Psychiatry Retrospective Studies SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 |
| SummonAdditionalLinks | – databaseName: ProQuest Central dbid: BENPR link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB7BFiEuvKGBFhmJAwisxq88TlVbWlEJlgpB1VvkOI6oVCVLknLix-PxOlktVXvhlsiOY2vGM-OZ8TcAb6zXGyynGa8tlZlWtNSG0YRXOlXKCOHLvZ1-Tufz7OwsPwkOtz6kVY4y0QvqqjXoI99xmseZMixXfHfxi2LVKIyuhhIat2EDkcrkDDb2D-cn3yZZzKQvkOx0NkYwUxmuzYTLc3HKKR6fYimVa19XTVfszatpk__ETr1KOnrwv4t5CPeDMUr2ltzzCG7Z5jHc_RLC7U_gz15DjgfvCSE-8xDnZDvS2aFrxzuadLF6Jm05eXndwB67lrQN8aiZQcoSRNyobb_MAehJW5ODr6fHHynLyds5Zhb613dP4cfR4feDTzSUa6BGpnKgJbNxZTgTNWOOMRDpRRtnYOVGGMGSpCwTYZlCgLRU2txKhuafsFYmsq5UIp7BrGkbuwkkyVRZ60prYWKpNddc6NIYoevKKFXaCNhIqcIELHMsqXFRrFCYkbqFo27hqVuwCN5P3yyWSB439t4aKVeEXd0XK7JF8HpqdvsRgyy6se2l76MwdBnLCJ4v-WX6nTNe3QmNu8HTNU6aOiDW93pLc_7TY36n3BmGIovgw8hzq2ldv4oXN6_iJdzjnv_RqbQFs6G7tNtwx_wezvvuVdhLfwGt4SWg priority: 102 providerName: ProQuest |
| Title | An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID) |
| URI | https://link.springer.com/article/10.1007/s10072-020-04450-1 https://www.ncbi.nlm.nih.gov/pubmed/32430621 https://www.proquest.com/docview/2409911952 https://www.proquest.com/docview/2405304904 https://pubmed.ncbi.nlm.nih.gov/PMC7235538 |
| Volume | 41 |
| WOSCitedRecordID | wos000534203700003&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAVX databaseName: SpringerLINK Contemporary 1997-Present customDbUrl: eissn: 1590-3478 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001413 issn: 1590-1874 databaseCode: RSV dateStart: 20000401 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB5BixAX3o9AWRmJAwgsxa84OZbSikrsUhVY7S1yHEdUQkmVpJz48dizSZalgASXKJYdx48Zz9gz8xnguUO5wTKa8spRmRpFC2MZTXhptFJWCLzubfleLxbpapWdDEFh3ejtPpokcaX-Kdgt1pyG7U4spYqp3_PsenGXBnY8_bic1l8m8VJkL6eD1VLLIVTm93Vsi6NLOuZlV8lf7KUoho5u_V8HbsPNQe0k-2s6uQNXXH0Xrs8Hw_o9-L5fk-MezzwI-hiGlriWtK5vmzEak55v3klTTOe5vmJEqSVNTRAfc1hPScDWqFy3tvZ3pKnIwYfl8VvKMvJiEXwIMfnyPnw-Ovx08I4OFzNQK7XsacFcXFrORMWYJ4GA6WKsV6UyK6xgSVIUiXBMBSg0LV3mJAuKnnBOJrIqVSIewE7d1O4RkCRVRWVKY4SNpTHccGEKa4WpSqtU4SJg4_zkdkAtD5dnfM03eMthWHM_rDkOa84ieDV9c77G7Phr6b1x2vOBf7vc6zlecWaZ4hE8m7I95wVziqldc4FlVDBSxjKCh2sqmX7n1VS_F-O-cr1FP1OBgOq9nVOffUF0b829CijSCF6PVLRp1p978fjfij-BGxwJMRwn7cFO3164p3DNfuvPunYGV_VK4zOdwe6bw8XJqU_NY3zy-Qz57QeomB9c |
| linkProvider | Springer Nature |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VgoAL78JCASOBBKIW61ceB4Sqlqqr7i4cStVbcBxHVELJkqQgJH4TvxGP81gtFb31wC2RHcdOPs-MPeNvAJ5brzdYTCOeWyojrWiqDaMBz3SolBHCp3s7mobzeXR8HH9cg9_9WRgMq-xlohfUWWlwj_yN0zzOlGGx4u8W3yhmjULvap9Co4XFgf35wy3Z6reTXfd_X3C-9_5wZ592WQWokaFsaMrsODOciZwx138kJNHG2QGxEUawIEjTQFimkMcrlDa2kqGVIqyVgcwzFQjX7iW4LN1KCFNFzPhskPxM-nTMzkJAf2kou0M63VG9ccgpLtbGUipXvqoIz1i3Z4M0__LUegW4d_N_-3S34EZnapPtdm7chjVb3IGrsy6Y4C782i7IpPH7PMTHVeI3sBWpbFOV_QlUulhekzId9rBdw56Zl5QF8ZygnQ4hyCeS27qNcKhJmZOdD0eTXcpi8nKOcZP-9tU9-HQhY9-A9aIs7AMgQaTSXGdaCzOWWnPNhU6NETrPjFKpHQHrkZGYjqkdE4Z8TZYc04imxKEp8WhK2AheD88sWp6Sc2tv9khJOplVJ0uYjODZUOykDbqQdGHLU19HoWN2LEdwv8Xn8Dpnmrv1J3eNhyvIHSogk_lqSXHyxTOah9yZvSIawVaP8WW3_j2Kh-eP4ilc2z-cTZPpZH7wCK5zP_dw-2wT1pvq1D6GK-Z7c1JXT_wsJvD5orH_B0gqfxI |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VgqpeeFMWChgJJBBYjV_J5oBQ1WXFqmWpEFS9BcdxRCWULEkKQuKX8evwOI_VUtFbD9wS2XEyzmfP2DP-BuCJ9XqDxXTMc0vlWCuaasNoyDMdKWWE8Onejg6i-Xx8fBwfrsHv_iwMhlX2c6KfqLPS4B75jtM8zpRhseI7eRcWcTiZvl58o5hBCj2tfTqNFiL79ucPt3yrX80m7l8_5Xz65uPeW9plGKBGRrKhKbNBZjgTOWNOFiQn0cbZBLERRrAwTNNQWKaQ0yuSNraSocUirJWhzDMVCtfuJbgcoXMQwwaDD4MWYNKnZnbWAvpOI9kd2OmO7QURp7hwC6RUrnxVKZ6xdM8GbP7ltfXKcHrtf-7G63C1M8HJbjtmbsCaLW7CxrsuyOAW_NotyKzx-z_Ex1tif9iKVLapyv5kKl0sr0mZDnvbrmHP2EvKgniu0E63EOQZyW3dRj7UpMzJ3vuj2YSymDybYzylv31-Gz5diOx3YL0oC3sXSDhWaa4zrYUJpNZcc6FTY4TOM6NUakfAepQkpmNwx0QiX5Ml9zQiK3HISjyyEjaCF8Mzi5a_5Nza2z1qkm4uq5MlZEbweCh2sxC6lnRhy1NfR6HDNpAj2GqxOrzOmexuXcpd49EKiocKyHC-WlKcfPFM5xF35rAYj-Blj_flZ_1binvnS_EINhzkk4PZfP8-bHI_DHFXbRvWm-rUPoAr5ntzUlcP_YAm8Pmiof8HVVyH3g |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=An+Italian+multicenter+retrospective-prospective+observational+study+on+neurological+manifestations+of+COVID-19+%28NEUROCOVID%29&rft.jtitle=Neurological+sciences&rft.au=Ferrarese%2C+Carlo&rft.au=Silani%2C+Vincenzo&rft.au=Priori%2C+Alberto&rft.au=Galimberti%2C+Stefania&rft.date=2020-06-01&rft.issn=1590-3478&rft.eissn=1590-3478&rft.volume=41&rft.issue=6&rft.spage=1355&rft_id=info:doi/10.1007%2Fs10072-020-04450-1&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1590-1874&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1590-1874&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1590-1874&client=summon |