The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

There is a pressing need for a gonorrhea vaccine due to the high disease burden associated with gonococcal infections globally and the rapid evolution of antibiotic resistance in Neisseria gonorrhoeae ( Ng ). Current gonorrhea vaccine research is in the stages of antigen discovery and the identifica...

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Bibliographic Details
Published in:	PLoS pathogens Vol. 16; no. 12; p. e1008602
Main Authors:	Leduc, Isabelle, Connolly, Kristie L., Begum, Afrin, Underwood, Knashka, Darnell, Stephen, Shafer, William M., Balthazar, Jacqueline T., Macintyre, Andrew N., Sempowski, Gregory D., Duncan, Joseph A., Little, Marguerite B., Rahman, Nazia, Garges, Eric C., Jerse, Ann E.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.12.2020 Public Library of Science (PLoS)
Subjects:	Animals Antigens, Bacterial - immunology Bacterial Outer Membrane Proteins - immunology Bacterial Vaccines - immunology Biology and Life Sciences Case-Control Studies Cross Protection - immunology Cross Reactions - immunology Female Gonorrhea - immunology Humans Immune Sera - immunology Immunization - methods Male Medicine and Health Sciences Meningococcal Infections - microbiology Meningococcal Vaccines - immunology Meningococcal Vaccines - metabolism Meningococcal Vaccines - pharmacology Mice Mice, Inbred BALB C Neisseria gonorrhoeae - immunology Neisseria meningitidis - immunology Neisseria meningitidis, Serogroup B - immunology Research and Analysis Methods Retrospective Studies Serogroup Vaccination - methods
ISSN:	1553-7374, 1553-7366, 1553-7374
Online Access:	Get full text
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