MicroRNA sequence codes for small extracellular vesicle release and cellular retention

Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-cell communication in which microRNAs (miRNAs) produced and released from one cell are taken up by cells at a distance where they can enact changes in gene expression 1 – 3 . However, the mechanism by which miRNA...

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Bibliographic Details
Published in:	Nature (London) Vol. 601; no. 7893; pp. 446 - 451
Main Authors:	Garcia-Martin, Ruben, Wang, Guoxiao, Brandão, Bruna B., Zanotto, Tamires M., Shah, Samah, Kumar Patel, Sandip, Schilling, Birgit, Kahn, C. Ronald
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 20.01.2022 Nature Publishing Group
Subjects:	38/77 38/91 42/44 45/41 45/70 631/337/384/331 631/443/319 82/58 96/106 96/109 Adipocytes Adipocytes - cytology Cell Communication Cell interactions Clonal deletion Endothelium Endothelium - cytology Exosomes Exosomes - genetics Exosomes - metabolism Extracellular vesicles Extracellular Vesicles - genetics Extracellular Vesicles - metabolism Gene expression Humanities and Social Sciences Insertion Liver - cytology MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA multidisciplinary Muscles Muscles - cytology Retention Ribonucleic acid RNA RNA-binding protein Science Science (multidisciplinary) Secretion
ISSN:	0028-0836, 1476-4687, 1476-4687
Online Access:	Get full text
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