Distinct biological ages of organs and systems identified from a multi-omics study

Biological age (BA) has been proposed to evaluate the aging status instead of chronological age (CA). Our study shows evidence that there might be multiple “clocks” within the whole-body system: systemic aging drivers/clocks overlaid with organ/tissue-specific counterparts. We utilize multi-omics da...

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Vydané v:	Cell reports (Cambridge) Ročník 38; číslo 10; s. 110459
Hlavní autori:	Nie, Chao, Li, Yan, Li, Rui, Yan, Yizhen, Zhang, Detao, Li, Tao, Li, Zhiming, Sun, Yuzhe, Zhen, Hefu, Ding, Jiahong, Wan, Ziyun, Gong, Jianping, Shi, Yanfang, Huang, Zhibo, Wu, Yiran, Cai, Kaiye, Zong, Yang, Wang, Zhen, Wang, Rong, Jian, Min, Jin, Xin, Wang, Jian, Yang, Huanming, Han, Jing-Dong J., Zhang, Xiuqing, Franceschi, Claudio, Kennedy, Brian K., Xu, Xun
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Elsevier Inc 08.03.2022 Elsevier
Predmet:	Aged, 80 and over Aging aging biomarker biological ages CLHLS Humans Longevity Longitudinal Studies Metabolomics multi-omics NHANES Nutrition Surveys organ aging multi-omics NHANES aging biomarker organ aging CLHLS biological ages
ISSN:	2211-1247, 2211-1247
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