Molecular interaction studies of Deguelin and its derivatives with Cyclin D1 and Cyclin E in cancer cell signaling pathway: The computational approach

Deguelin is a major active ingredient and principal component in several plants and it is a potential molecule to target proteins of cancer cell signaling pathway. As a complex natural extract, deguelin interacts with various molecular targets to exert its anti-tumor properties at nanomolar level. I...

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Vydáno v:	Scientific reports Ročník 9; číslo 1; s. 1778
Hlavní autoři:	Lokhande, Kiran Bharat, Nagar, Shuchi, Swamy, K. Venkateswara
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 11.02.2019 Nature Publishing Group
Témata:	119/118 631/67/1059/153 692/699/67 Apoptosis Cancer Cell cycle Computer applications Conformation Cyclin D1 Cyclin E Humanities and Social Sciences Hydrogen bonding Ligands Molecular dynamics multidisciplinary Science Science (multidisciplinary) Signal transduction
ISSN:	2045-2322, 2045-2322
On-line přístup:	Získat plný text
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