Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitro

Lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), the causative agent of Lassa fever (LF), have extensive strain diversity and significant variations in pathogenicity for humans and experimental animals. The WE strain of LCMV (LCMV-WE), but not the Armstron...

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Veröffentlicht in:	Journal of virology Jg. 86; H. 13; S. 7216
Hauptverfasser:	Hayes, Melissa W, Carrion, Jr, Ricardo, Nunneley, Jerritt, Medvedev, Andrei E, Salvato, Maria S, Lukashevich, Igor S
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2012
Schlagworte:	Animals Cell Line Cytokines - antagonists & inhibitors Humans Immune Evasion Lassa virus - immunology Lassa virus - pathogenicity Lymphocytic choriomeningitis virus - immunology Lymphocytic choriomeningitis virus - pathogenicity Membrane Transport Proteins - immunology Mice Mice, Inbred C57BL Mice, Knockout Myelin and Lymphocyte-Associated Proteolipid Proteins Myelin Proteins - antagonists & inhibitors Myelin Proteins - immunology NF-kappa B - antagonists & inhibitors NF-kappa B - immunology Proteolipids - antagonists & inhibitors Proteolipids - immunology Toll-Like Receptor 2 - antagonists & inhibitors Toll-Like Receptor 2 - immunology
ISSN:	1098-5514, 1098-5514
Online-Zugang:	Weitere Angaben
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