Toll-like receptor 3 as a new marker to detect high risk early stage Non-Small-Cell Lung Cancer patients

Immune and epithelial cells express TLR3, a receptor deputed to respond to microbial signals activating the immune response. The prognostic value of TLR3 in cancer is debated and no data are currently available in NSCLC, for which therapeutic approaches that target the immune system are providing en...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; pp. 14288 - 10
Main Authors:	Bianchi, Francesca, Milione, Massimo, Casalini, Patrizia, Centonze, Giovanni, Le Noci, Valentino M., Storti, Chiara, Alexiadis, Spyridon, Truini, Mauro, Sozzi, Gabriella, Pastorino, Ugo, Balsari, Andrea, Tagliabue, Elda, Sfondrini, Lucia
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 03.10.2019 Nature Publishing Group
Subjects:	13/51 14/63 38/39 631/250/580 631/67/1612/1350 631/67/1857 82/1 Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Epithelial cells Female Gene Expression Regulation, Neoplastic Humanities and Social Sciences Humans Immune response Immune system Immunohistochemistry Kaplan-Meier Estimate Lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - genetics Lung Neoplasms - pathology Macrophages Male Medical prognosis Middle Aged multidisciplinary Non-small cell lung carcinoma Patients PD-1 protein Prognosis Science Science (multidisciplinary) Small cell lung carcinoma Stroma Surgery TLR3 protein Toll-Like Receptor 3 - analysis Toll-Like Receptor 3 - genetics Toll-like receptors Tumor cells Tumors
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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