Permethrin induced arterial retention of native and oxidized LDL in rats by promoting inflammation, oxidative stress and affecting LDL receptors, and collagen genes

This study is the first to examine the possible mechanism by which long-term exposure to permethrin (PER) can promote arterial retention of proatherogenic lipid and lipoproteins and related vascular dysfunction in rats. Experimental animals were administered two doses of oral PER, PER-1 (2.5 mg/kg/b...

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Bibliographic Details
Published in:	Ecotoxicology and environmental safety Vol. 207; p. 111269
Main Authors:	Feriani, Anouar, Tir, Meriam, Hachani, Rafik, Allagui, Mohamed Salah, Tlili, Nizar, Nahdi, Saber, Alwasel, Saleh, Harrath, Abdel Halim
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 01.01.2021 Elsevier
Subjects:	Animals Aorta Aorta - metabolism Aorta - pathology Apolipoprotein B-100 - metabolism CD36 Antigens - metabolism Collagen Collagen - genetics Inflammation - metabolism Insecticides - toxicity LDL LDL and CD36 receptors Lipids - blood Lipoproteins, LDL - blood Male Malondialdehyde - metabolism Oxidation-Reduction Oxidative stress Oxidative Stress - physiology Permethrin Permethrin - toxicity Rats Reactive Oxygen Species - metabolism Receptors, LDL - metabolism Tumor Necrosis Factor-alpha - metabolism Oxidative stress Aorta Permethrin LDL and CD36 receptors LDL Collagen
ISSN:	0147-6513, 1090-2414, 1090-2414
Online Access:	Get full text
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