A framework for tracer-based metabolism in mammalian cells by NMR

Metabolism changes extensively during the normal proliferation and differentiation of mammalian cells, and in cancer and inflammatory diseases. Since changes in the metabolic network reflect interactions between genetic, epigenetic and environmental changes, it is helpful to study the flow of label...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; p. 2520
Main Authors:	Saborano, Raquel, Eraslan, Zuhal, Roberts, Jennie, Khanim, Farhat L., Lalor, Patricia F., Reed, Michelle A. C., Günther, Ulrich L.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 21.02.2019 Nature Publishing Group
Subjects:	101/6 140/131 631/45/56 631/61/320 631/92/56 Animals Carbon Isotopes - chemistry Carbon Isotopes - pharmacology Cell proliferation Environmental changes Hepatocytes Humanities and Social Sciences Humans Inflammatory diseases Isotope Labeling - methods Liver cancer Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Mammalian cells Mammals Metabolic Networks and Pathways - genetics Metabolism Metabolism - genetics Metabolites multidisciplinary NMR Nuclear magnetic resonance Science Science (multidisciplinary) Spectroscopy Spectrum analysis Tumor cell lines Workflow
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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