Identification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma

Aberrant methylated genes (DMGs) play an important role in the etiology and pathogenesis of esophageal squamous cell carcinoma (ESCC). In this study, we aimed to integrate three cohorts profile datasets to ascertain aberrant methylated-differentially expressed genes and pathways associated with ESCC...

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Vydáno v:	Scientific reports Ročník 10; číslo 1; s. 9735
Hlavní autoři:	Han, Bao-Ai, Yang, Xiu-Ping, Hosseini, Davood K, Zhang, Po, Zhang, Ya, Yu, Jin-Tao, Chen, Shan, Zhang, Fan, Zhou, Tao, Sun, Hai-Ying
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 16.06.2020 Nature Publishing Group
Témata:	119/118 631/67/2324 631/67/68/2486 9/10 AKT protein Bioinformatics Biomarkers, Tumor - genetics Cell cycle Cohort Studies Computational Biology Databases, Genetic DNA methylation DNA Methylation - genetics DNA microarrays Esophageal cancer Esophageal Neoplasms - genetics Esophageal Squamous Cell Carcinoma - genetics Esophageal Squamous Cell Carcinoma - metabolism Esophagus Etiology Gene expression Gene Expression - genetics Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Gene Ontology Gene Regulatory Networks Genomes Humanities and Social Sciences Humans Methylation Microarray Analysis Molecular modelling multidisciplinary Protein interaction Protein Interaction Maps - genetics Science Science (multidisciplinary) Signal transduction Signal Transduction - genetics Software Squamous cell carcinoma Transcriptome - genetics
ISSN:	2045-2322, 2045-2322
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