Extensive weight loss reduces glycan age by altering IgG N-glycosylation

Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent posttranslational modification, highly responsive to inflammation and ageing. The prospect of biological age reduction, by changing glycosylation patterns...

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Vydáno v:	International Journal of Obesity Ročník 45; číslo 7; s. 1521 - 1531
Hlavní autoři:	Greto, Valentina L, Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J, Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S, Tomlinson, Jeremy W, Gornik, Olga, Sgromo, Bruno, Spector, Tim D, Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V, Lauc, Gordan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Nature Publishing Group 01.07.2021
Témata:	Adult Age Aging Aging - physiology Bariatric Surgery Body Mass Index Body weight loss Calories Diet Female Gastrointestinal surgery Global health Glycan Glycosylation Humans Hypocaloric diet Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - chemistry Inflammation Longitudinal Studies Male Middle Aged Morbidity N-glycans Nutrient deficiency Obesity Obesity - blood Obesity - metabolism Polysaccharides Public health Surgery Twins Weight control Weight loss Weight Loss - physiology Weight reduction
ISSN:	0307-0565, 1476-5497, 1476-5497
On-line přístup:	Získat plný text
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