Extensive weight loss reduces glycan age by altering IgG N-glycosylation

Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent posttranslational modification, highly responsive to inflammation and ageing. The prospect of biological age reduction, by changing glycosylation patterns...

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Bibliographic Details
Published in:	International Journal of Obesity Vol. 45; no. 7; pp. 1521 - 1531
Main Authors:	Greto, Valentina L, Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J, Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S, Tomlinson, Jeremy W, Gornik, Olga, Sgromo, Bruno, Spector, Tim D, Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V, Lauc, Gordan
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.07.2021
Subjects:	Adult Age Aging Aging - physiology Bariatric Surgery Body Mass Index Body weight loss Calories Diet Female Gastrointestinal surgery Global health Glycan Glycosylation Humans Hypocaloric diet Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - chemistry Inflammation Longitudinal Studies Male Middle Aged Morbidity N-glycans Nutrient deficiency Obesity Obesity - blood Obesity - metabolism Polysaccharides Public health Surgery Twins Weight control Weight loss Weight Loss - physiology Weight reduction
ISSN:	0307-0565, 1476-5497, 1476-5497
Online Access:	Get full text
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