Diagnostics for SARS-CoV-2 infections

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache....

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Vydáno v:	Nature materials Ročník 20; číslo 5; s. 593 - 605
Hlavní autoři:	Kevadiya, Bhavesh D., Machhi, Jatin, Herskovitz, Jonathan, Oleynikov, Maxim D., Blomberg, Wilson R., Bajwa, Neha, Soni, Dhruvkumar, Das, Srijanee, Hasan, Mahmudul, Patel, Milankumar, Senan, Ahmed M., Gorantla, Santhi, McMillan, JoEllyn, Edagwa, Benson, Eisenberg, Robert, Gurumurthy, Channabasavaiah B., Reid, St Patrick M., Punyadeera, Chamindie, Chang, Linda, Gendelman, Howard E.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 01.05.2021 Nature Publishing Group
Témata:	631/154 631/1647 631/250 631/326 631/61 Antibodies, Viral - blood Antigens, Viral - analysis Biomaterials Brain - diagnostic imaging Chemistry and Materials Science Condensed Matter Physics Coronaviruses COVID-19 COVID-19 - diagnosis COVID-19 - diagnostic imaging COVID-19 - virology COVID-19 Nucleic Acid Testing - methods COVID-19 Serological Testing - methods COVID-19 Testing - methods Diagnosis Headache High-Throughput Nucleotide Sequencing - methods Humans Lung - diagnostic imaging Materials Science Metagenomics - methods Muscles Nanomaterials Nanostructures Nanotechnology Olfaction disorders Optical and Electronic Materials Pandemics Physicians Respiratory diseases Respiratory tract Review Article SARS-CoV-2 - genetics SARS-CoV-2 - immunology SARS-CoV-2 - isolation & purification Severe acute respiratory syndrome coronavirus 2 Taste disorders Viral diseases Viral Load Virus Shedding
ISSN:	1476-1122, 1476-4660, 1476-4660
On-line přístup:	Získat plný text
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Popis
Shrnutí:	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large. This Review highlights the progress that has been made in the development of diagnostic tools for the detection of SARS-CoV-2 in the fight against COVID-19.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 BDK and HEG conceptualized, organized, designed, interpreted and facilitated the writing of the manuscript. BDK conceptualized then created each of the figures and figure legends. BDK and JM edited, wrote and revised the text. BDK, HEG, JM, JH, MDO, NB, DS, SD, MP, AMS, SG, CP and LC wrote sections and edited the manuscript; BDK, JM, HEG, JMM, WRB, BE, CBG, MH, SPMR and RE structured the review, proofed and edited the text. All authors read and approved the final manuscript contents. Authors contribution
ISSN:	1476-1122 1476-4660 1476-4660
DOI:	10.1038/s41563-020-00906-z