Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer

Background There is a need to improve the treatment of prostate cancer (PCa) and reduce treatment side effects. Vascular-targeted photodynamic therapy (VTP) is a focal therapy for low-risk low-volume localised PCa, which rapidly disrupts targeted tumour vessels. There is interest in expanding the us...

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Bibliographic Details
Published in:	British journal of cancer Vol. 125; no. 4; pp. 534 - 546
Main Authors:	Sjoberg, Hanna T., Philippou, Yiannis, Magnussen, Anette L., Tullis, Iain D. C., Bridges, Esther, Chatrian, Andrea, Lefebvre, Joel, Tam, Ka Ho, Murphy, Emma A., Rittscher, Jens, Preise, Dina, Agemy, Lilach, Yechezkel, Tamar, Smart, Sean C., Kinchesh, Paul, Gilchrist, Stuart, Allen, Danny P., Scheiblin, David A., Lockett, Stephen J., Wink, David A., Lamb, Alastair D., Mills, Ian G., Harris, Adrian, Muschel, Ruth J., Vojnovic, Boris, Scherz, Avigdor, Hamdy, Freddie C., Bryant, Richard J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 17.08.2021 Nature Publishing Group
Subjects:	631/67/1059/485 692/4028/546 Allografts Animals Biomedical and Life Sciences Biomedicine Cancer Research Cell Line, Tumor Clinical trials Combined Modality Therapy Dose Fractionation, Radiation Drug Resistance Epidemiology Human Umbilical Vein Endothelial Cells Humans Magnetic resonance imaging Male Mice Microenvironments Molecular Medicine Neovascularization, Pathologic - therapy Oncology Permeability Photochemotherapy - methods Photodynamic therapy Prostate cancer Prostatic Neoplasms - blood supply Prostatic Neoplasms - therapy Radiation therapy Survival Analysis Tumor Microenvironment Tumors Xenograft Model Antitumor Assays
ISSN:	0007-0920, 1532-1827, 1532-1827
Online Access:	Get full text
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