Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto’s thyroiditis

Thyroid antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) are key markers of Hashimoto’s thyroiditis (HT), the most common autoimmune thyroid disorder. Genetic determinants of thyroid antibodies are still poorly known, especially as they were not studied in patients with thyroid...

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Vydáno v:	Scientific reports Ročník 9; číslo 1; s. 5360 - 10
Hlavní autoři:	Brčić, Luka, Barić, Ana, Gračan, Sanda, Torlak, Vesela, Brekalo, Marko, Škrabić, Veselin, Zemunik, Tatijana, Barbalić, Maja, Punda, Ante, Boraska Perica, Vesna
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 29.03.2019 Nature Publishing Group
Témata:	45/43 631/208/205/2138 631/250/38 692/163/2743/1841 Adult Antibodies Association analysis Autoantibodies - genetics Autoantibodies - immunology Autoimmune diseases Autoimmunity Biomarkers Female Genetic Association Studies Genetic diversity Genetic Loci Genetic Predisposition to Disease Genetic variance Genetic Variation Genome-Wide Association Study Genomes Hashimoto Disease - diagnosis Hashimoto Disease - etiology Humanities and Social Sciences Humans Immunoglobulins Iodide peroxidase Male Middle Aged multidisciplinary Peroxidase Science Science (multidisciplinary) Thyroglobulin Thyroid Thyroid diseases Thyroid Gland - immunology Thyroid Gland - metabolism Thyroiditis
ISSN:	2045-2322, 2045-2322
On-line přístup:	Získat plný text
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