SARS-CoV-2 variant biology: immune escape, transmission and fitness

In late 2020, after circulating for almost a year in the human population, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its adaptation to humans. These highly mutated forms of SARS-CoV-2 had enhanced rates of transmission relative to previous variants...

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Veröffentlicht in:	Nature reviews. Microbiology Jg. 21; H. 3; S. 162 - 177
Hauptverfasser:	Carabelli, Alessandro M, Peacock, Thomas P, Thorne, Lucy G, Harvey, William T, Hughes, Joseph, Peacock, Sharon J, Barclay, Wendy S, de Silva, Thushan I, Towers, Greg J, Robertson, David L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.03.2023
Schlagworte:	Antigenicity Biology Coronaviruses COVID-19 Disease transmission Evolution Fitness Furin Herd immunity Human populations Humans Immune evasion Immune response Immune system Immunity Immunity, Innate Infectivity Innate immunity Literature reviews Lymphocytes Lymphocytes T Mutation Recombination Reproductive fitness Respiratory diseases SARS-CoV-2 - genetics Severe acute respiratory syndrome coronavirus 2 Vaccination Viral diseases Virulence Viruses
ISSN:	1740-1526, 1740-1534, 1740-1534
Online-Zugang:	Volltext
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