Therapeutic targeting of acute myeloid leukemia stem cells

For more than 50 years, investigators have considered a malignant stem cell as the potential origin of and a key therapeutic target for acute myeloid leukemia (AML) and other forms of cancer. The nature and existence of tumor-initiating cells for leukemia and other malignancies have long been the su...

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Vydané v:	Blood Ročník 129; číslo 12; s. 1627 - 1635
Hlavní autori:	Pollyea, Daniel A, Jordan, Craig T
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 23.03.2017
Predmet:	Humans Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - pathology Molecular Targeted Therapy - methods Molecular Targeted Therapy - trends Neoplastic Stem Cells - pathology Signal Transduction - drug effects
ISSN:	1528-0020
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