Solution NMR backbone assignment reveals interaction-free tumbling of human lineage-specific Olduvai protein domains

Olduvai protein domains, encoded primarily by NBPF genes, have been linked to both human brain evolution and cognitive diseases such as autism and schizophrenia. There are six primary domains that comprise the Olduvai family: three conserved domains (CON1-3) and three human lineage-specific domains...

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Bibliographic Details
Published in:	Biomolecular NMR assignments Vol. 13; no. 2; pp. 339 - 343
Main Authors:	Issaian, Aaron, Schmitt, Lauren, Born, Alexandra, Nichols, Parker J., Sikela, James, Hansen, Kirk, Vögeli, Beat, Henen, Morkos A.
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.10.2019 Springer Nature B.V
Subjects:	Autism Biochemistry Biological and Medical Physics Biophysics Cognitive ability Evolutionary genetics Humans Intracellular Signaling Peptides and Proteins - chemistry Mental disorders NMR Nuclear magnetic resonance Nuclear Magnetic Resonance, Biomolecular Physics Physics and Astronomy Polymer Sciences Protein Domains Schizophrenia Solutions Tumbling DUF1220 Autism Protein domains Schizophrenia Gene duplication Brain evolution Backbone chemical shift assignment Olduvai
ISSN:	1874-2718, 1874-270X, 1874-270X
Online Access:	Get full text
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