Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis

ABSTRACT Introduction: Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis. Methods: We compared serum microRNA (miRNA) expression from patients with ALS with healthy controls and patients with...

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Bibliographic Details
Published in:	Muscle & nerve Vol. 58; no. 2; pp. 261 - 269
Main Authors:	Raheja, Radhika, Regev, Keren, Healy, Brian C., Mazzola, Maria Antonietta, Beynon, Vanessa, Von Glehn, Felipe, Paul, Anu, Diaz‐Cruz, Camilo, Gholipour, Taha, Glanz, Bonnie I., Kivisakk, Pia, Chitnis, Tanuja, Weiner, Howard L., Berry, James D., Gandhi, Roopali
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.08.2018
Subjects:	Adult ALS Alzheimer Disease - blood Alzheimer Disease - physiopathology Alzheimer's disease Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - blood Amyotrophic Lateral Sclerosis - physiopathology Biomarkers Biomarkers - blood Cohort Studies Cross-Sectional Studies Diagnosis disease comparisons Disease control Disease Progression Female Gene Expression Regulation Humans longitudinal analysis Longitudinal Studies Male Medical prognosis microRNA MicroRNAs - blood Middle Aged miRNA Multiple sclerosis Multiple Sclerosis - blood Multiple Sclerosis - physiopathology Muscles Neurodegenerative diseases Parameter identification Patients Ribonucleic acid RNA serum ALS longitudinal analysis microRNA disease comparisons serum biomarkers
ISSN:	0148-639X, 1097-4598, 1097-4598
Online Access:	Get full text
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