Idiopathic intracranial hypertension: Pathophysiology, diagnosis and management
•The population burden of IIH is projected to rise with increasing rates of obesity.•Recent studies highlight the pathogenic role of metabolic and hormonal factors.•Neuroimaging and lumbar puncture assessment are required for the diagnosis of IIH.•A majority of IIH patients respond to weight loss an...
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| Vydáno v: | Journal of clinical neuroscience Ročník 95; s. 172 - 179 |
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Elsevier Ltd
01.01.2022
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| ISSN: | 0967-5868, 1532-2653, 1532-2653 |
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| Abstract | •The population burden of IIH is projected to rise with increasing rates of obesity.•Recent studies highlight the pathogenic role of metabolic and hormonal factors.•Neuroimaging and lumbar puncture assessment are required for the diagnosis of IIH.•A majority of IIH patients respond to weight loss and/or acetazolamide therapy.•Surgical interventions are available for those refractory to medical treatment.
Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. The pathophysiology involves dysregulation of cerebrospinal fluid (CSF) dynamics and venous sinus pressure, and recent studies highlighting the pathogenic role of metabolic and hormonal factors have led to the identification of several pharmacological targets and development of novel therapeutic agents. The overarching treatment goals include symptomatic alleviation and prevention of permanent vision loss. The Idiopathic Intracranial Hypertension Treatment Trial, the first of its kind randomized controlled trial on IIH, provides class I evidence for treatment with weight loss and acetazolamide. In medically refractive or fulminant cases, optic nerve sheath fenestration, CSF diversion, and venous sinus stenting, have been successfully implemented. However, there are few high-quality prospective studies investigating the treatment and natural history of IIH, highlighting the compelling need for further research to determine the optimal treatment regimen. |
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| AbstractList | •The population burden of IIH is projected to rise with increasing rates of obesity.•Recent studies highlight the pathogenic role of metabolic and hormonal factors.•Neuroimaging and lumbar puncture assessment are required for the diagnosis of IIH.•A majority of IIH patients respond to weight loss and/or acetazolamide therapy.•Surgical interventions are available for those refractory to medical treatment.
Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. The pathophysiology involves dysregulation of cerebrospinal fluid (CSF) dynamics and venous sinus pressure, and recent studies highlighting the pathogenic role of metabolic and hormonal factors have led to the identification of several pharmacological targets and development of novel therapeutic agents. The overarching treatment goals include symptomatic alleviation and prevention of permanent vision loss. The Idiopathic Intracranial Hypertension Treatment Trial, the first of its kind randomized controlled trial on IIH, provides class I evidence for treatment with weight loss and acetazolamide. In medically refractive or fulminant cases, optic nerve sheath fenestration, CSF diversion, and venous sinus stenting, have been successfully implemented. However, there are few high-quality prospective studies investigating the treatment and natural history of IIH, highlighting the compelling need for further research to determine the optimal treatment regimen. Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. The pathophysiology involves dysregulation of cerebrospinal fluid (CSF) dynamics and venous sinus pressure, and recent studies highlighting the pathogenic role of metabolic and hormonal factors have led to the identification of several pharmacological targets and development of novel therapeutic agents. The overarching treatment goals include symptomatic alleviation and prevention of permanent vision loss. The Idiopathic Intracranial Hypertension Treatment Trial, the first of its kind randomized controlled trial on IIH, provides class I evidence for treatment with weight loss and acetazolamide. In medically refractive or fulminant cases, optic nerve sheath fenestration, CSF diversion, and venous sinus stenting, have been successfully implemented. However, there are few high-quality prospective studies investigating the treatment and natural history of IIH, highlighting the compelling need for further research to determine the optimal treatment regimen.Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. The pathophysiology involves dysregulation of cerebrospinal fluid (CSF) dynamics and venous sinus pressure, and recent studies highlighting the pathogenic role of metabolic and hormonal factors have led to the identification of several pharmacological targets and development of novel therapeutic agents. The overarching treatment goals include symptomatic alleviation and prevention of permanent vision loss. The Idiopathic Intracranial Hypertension Treatment Trial, the first of its kind randomized controlled trial on IIH, provides class I evidence for treatment with weight loss and acetazolamide. In medically refractive or fulminant cases, optic nerve sheath fenestration, CSF diversion, and venous sinus stenting, have been successfully implemented. However, there are few high-quality prospective studies investigating the treatment and natural history of IIH, highlighting the compelling need for further research to determine the optimal treatment regimen. Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the absence of an identifiable casual factor. The primary symptoms include headache, vision loss, and pulsatile tinnitus, and are recognized to have profound impacts on quality of life and visual function. IIH demonstrates a strong predilection towards obese women of reproductive age, and the population incidence is rising with the growing prevalence of obesity worldwide. The pathophysiology involves dysregulation of cerebrospinal fluid (CSF) dynamics and venous sinus pressure, and recent studies highlighting the pathogenic role of metabolic and hormonal factors have led to the identification of several pharmacological targets and development of novel therapeutic agents. The overarching treatment goals include symptomatic alleviation and prevention of permanent vision loss. The Idiopathic Intracranial Hypertension Treatment Trial, the first of its kind randomized controlled trial on IIH, provides class I evidence for treatment with weight loss and acetazolamide. In medically refractive or fulminant cases, optic nerve sheath fenestration, CSF diversion, and venous sinus stenting, have been successfully implemented. However, there are few high-quality prospective studies investigating the treatment and natural history of IIH, highlighting the compelling need for further research to determine the optimal treatment regimen. |
| Author | Danesh-Meyer, Helen V. Wang, Michael T.M. Bhatti, M. Tariq |
| Author_xml | – sequence: 1 givenname: Michael T.M. surname: Wang fullname: Wang, Michael T.M. organization: Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand – sequence: 2 givenname: M. Tariq surname: Bhatti fullname: Bhatti, M. Tariq organization: Departments of Ophthalmology and Neurology, Mayo Clinic College of Medicine, Rochester, MN, United States – sequence: 3 givenname: Helen V. surname: Danesh-Meyer fullname: Danesh-Meyer, Helen V. email: helendm@gmail.com organization: Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand |
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| Cites_doi | 10.1212/WNL.0000000000001687 10.6064/2012/708042 10.1159/000435919 10.1212/WNL.0b013e3182a55f17 10.1016/j.ajo.2006.12.040 10.1136/jnnp.45.1.13 10.1016/0014-2999(78)90035-3 10.1136/jnnp-2016-315106.14 10.1038/s41433-018-0238-5 10.1177/0333102415570762 10.1177/112067210401400108 10.1126/scitranslmed.aan0972 10.1186/s12987-019-0129-6 10.1111/j.1365-2265.2008.03401.x 10.1097/WNO.0000000000000648 10.1177/0333102410375726 10.1001/jamaophthalmol.2020.4242 10.1136/bmjopen-2017-017426 10.1016/j.jpeds.2013.01.048 10.1212/WNL.0000000000009312 10.1212/WNL.42.4.851 10.1016/j.ophtha.2009.03.056 10.1136/archdischild-2012-301885.14 10.1007/s00415-010-5861-4 10.1136/bjophthalmol-2014-304953 10.1136/jnnp-2017-317440 10.1093/brain/83.3.454 10.1167/iovs.08-2528 10.1136/bmj.c2701 10.2214/AJR.12.9638 10.1007/s10072-013-1373-1 10.1111/ene.12442 10.3171/2017.8.JNS17459 10.1111/ene.13893 10.3109/02713683.2013.799214 10.1016/S0022-3565(25)29822-6 10.1097/WNO.0000000000000815 10.1001/jama.2014.3312 10.1210/jc.2010-0729 10.1016/j.nrl.2013.08.009 10.1007/BF00612116 10.1093/braincomms/fcz050 10.1172/jci.insight.125348 10.1001/jamaneurol.2019.1812 10.1007/s10143-020-01288-1 10.1177/088307389400900205 10.1001/archneur.1978.00500250041009 10.1016/S0008-4182(05)80100-0 10.1016/j.ophtha.2017.06.016 10.1055/s-0034-1396333 10.1111/j.1600-0404.2007.00905.x 10.1016/j.ophtha.2017.01.006 10.1001/jamaneurol.2014.133 10.1186/2045-8118-11-12 10.1113/JP275105 10.1007/s004150070182 10.1016/j.ajo.2016.12.017 |
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| Keywords | Pseudotumor cerebri Therapy Complications Intracranial hypertension Cerebrospinal fluid Diagnosis Venous sinus |
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| References | Malm, Kristensen, Markgren, Ekstedt (b0115) 1992; 42 Brettschneider, Hartmann, Lehmensiek, Mogel, Ludolph, Tumani (b0190) 2011; 31 Avisar, Gaton, Dania, Stiebel-Kalish (b0090) 2012; 2012 McDougall, Ban, Beecher, Pride, Welch (b0130) 2018; 130 Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. Bmj. 2010;341:c2701. Welch, Friedman (b0125) 1960; 83 Rebolleda, Muñoz-Negrete (b0235) 2009; 50 McCluskey, Mulholland, McCarron, McCarron (b0065) 2015; 45 Botfield, Uldall, Westgate, Mitchell, Hagen, Gonzalez (b0165) 2017; 9 Huang‐Link, Eleftheriou, Yang, Johansson, Apostolou, Link (b0250) 2019; 26 Ney, Volpe, Liu, Balcer, Moster, Galetta (b0260) 2009; 116 Adderley, Subramanian, Nirantharakumar, Yiangou, Gokhale, Mollan (b0015) 2019; 76 Salpietro, Chimenz, Arrigo, Ruggieri (b0085) 2013; 162 Saindane, Bruce, Riggeal, Newman, Biousse (b0135) 2013; 201 Gideon, Sorensen, Thomsen, Stahlberg, Gjerris, Henriksen (b0120) 1994; 36 Altıokka-Uzun, Tüzün, Ekizoğlu, Ulusoy, Yentür, Kürtüncü (b0145) 2015; 35 Arregui, Iversen (b0185) 1978; 52 O'Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, et al. A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics. JCI Insight. 2019;4. Kuehn MH, Mishra R, Deonovic BE, Miller KN, McCormack SE, Liu GT, et al. Genetic Survey of Adult-Onset Idiopathic Intracranial Hypertension. J Neuroophthalmol. 2019;39:50-5. Wall, Kupersmith, Kieburtz, Corbett, Feldon, Friedman (b0010) 2014; 71 Hermes, Miller, Waslo, Benes, Tanne (b0095) 2020; 95 Pizzo, Wolak, Kumar, Brunette, Brunnquell, Hannocks (b0110) 2018; 596 Kilgore, Lee, Leavitt, Mokri, Hodge, Frank (b0025) 2017; 124 Kupersmith, Sibony, Feldon, Wang, Garvin, Kardon (b0240) 2017; 176 . Friedman, Liu, Digre (b0005) 2013; 81 Carta, Bertuzzi, Cologno, Giorgi, Montanari, Tedesc0 (b0055) 2004; 14 Schoeman (b0290) 1994; 9 Vijay, Mollan, Mitchell, Bilton, Alimajstorovic, Markey (b0245) 2020; 138 Matthews, Dean, Matyka, McLachlan, Solanki, Lim (b0070) 2012; 97 Contreras-Martin, Bueno-Perdomo (b0060) 2015; 30 Wall, Dalali (b0210) 1989; 43 Klein, Stern, Osher, Kliper, Kesler (b0160) 2013; 38 Wall, McDermott, Kieburtz, Corbett, Feldon, Friedman (b0035) 2014; 311 Levin (b0220) 1978; 35 Neville, Egan (b0270) 2005; 40 Yabe, Moriwaka, Notoya, Ohtaki, Tashiro (b0050) 2000; 247 Panagopoulos, Deftereos, Tagaris, Gryllia, Kounadi, Karamani (b0300) 2007; 1 Sinclair, Walker, Burdon, van Beek, Kema, Hughes (b0175) 2010; 95 Steinegger, Bergin, Guex-Crosier (b0265) 2015; 232 ISRCTN registry [Internet]. London: BMC. Identifier ISRCTN12678718, IIH Pressure - a new treatment for raised brain pressure in Idiopathic Intracranial Hypertension; Aug 11, 2017 [cited Oct 4, 2020 ]; Available from Kalyvas, Neromyliotis, Koutsarnakis, Komaitis, Drosos, Skandalakis (b0045) 2021; 44 Hornby, O'Reilly, Botfield, Markey, Kempegowda, Taylor (b0155) 2016; 87 Marzoli, Ciasca, Curone, Cammarata, Melzi, Criscuoli (b0225) 2013; 34 McCarthy, Reed (b0280) 1974; 189 Mollan, Davies, Silver, Shaw, Mallucci, Wakerley (b0030) 2018; 89 Ball AK, Sinclair AJ, Curnow SJ, Tomlinson JW, Burdon MA, Walker EA, et al. Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance? Clin Endocrinol (Oxf). 2009;70:863-9. Murtha, Yang, Parsons, Levi, Beard, Spratt (b0105) 2014; 11 Wall, George (b0205) 1991; 114(Pt 1A) Ball, Howman, Wheatley, Burdon, Matthews, Jacks (b0285) 2011; 258 Markey K, Mitchell J, Botfield H, Ottridge RS, Matthews T, Krishnan A, et al. 11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial. Brain Communications. 2020;2. Bothwell, Janigro, Patabendige (b0100) 2019; 16 Fonseca, Rigamonti, Miller, Subramanian (b0305) 2014; 98 Daniels, Liu, Volpe, Galetta, Moster, Newman (b0080) 2007; 143 McHugh JA, D’Antona L, Toma AK, Bremner FD. Spontaneous Venous Pulsations Detected With Infrared Videography. J Neuroophthalmol 2020;40:174-7. Ottridge, Mollan, Botfield, Frew, Ives, Matthews (b0275) 2017; 7 Çelebisoy, Gökçay, Şirin, Akyürekli (b0295) 2007; 116 Digre, Bruce, McDermott, Galetta, Balcer, Wall (b0200) 2015; 84 Kesler, Stolovic, Bluednikov, Shohat (b0075) 2014; 21 Frisen (b0215) 1982; 45 Chang, Velez, Demer, Bonelli, Quiros, Arnold (b0230) 2017; 124 Mollan, Aguiar, Evison, Frew, Sinclair (b0020) 2019; 33 Ottridge (10.1016/j.jocn.2021.11.029_b0275) 2017; 7 McCluskey (10.1016/j.jocn.2021.11.029_b0065) 2015; 45 Saindane (10.1016/j.jocn.2021.11.029_b0135) 2013; 201 10.1016/j.jocn.2021.11.029_b0255 Murtha (10.1016/j.jocn.2021.11.029_b0105) 2014; 11 Levin (10.1016/j.jocn.2021.11.029_b0220) 1978; 35 Arregui (10.1016/j.jocn.2021.11.029_b0185) 1978; 52 Botfield (10.1016/j.jocn.2021.11.029_b0165) 2017; 9 Marzoli (10.1016/j.jocn.2021.11.029_b0225) 2013; 34 Matthews (10.1016/j.jocn.2021.11.029_b0070) 2012; 97 Panagopoulos (10.1016/j.jocn.2021.11.029_b0300) 2007; 1 10.1016/j.jocn.2021.11.029_b0140 10.1016/j.jocn.2021.11.029_b0180 Avisar (10.1016/j.jocn.2021.11.029_b0090) 2012; 2012 Frisen (10.1016/j.jocn.2021.11.029_b0215) 1982; 45 Carta (10.1016/j.jocn.2021.11.029_b0055) 2004; 14 Wall (10.1016/j.jocn.2021.11.029_b0010) 2014; 71 Chang (10.1016/j.jocn.2021.11.029_b0230) 2017; 124 Neville (10.1016/j.jocn.2021.11.029_b0270) 2005; 40 Pizzo (10.1016/j.jocn.2021.11.029_b0110) 2018; 596 Ney (10.1016/j.jocn.2021.11.029_b0260) 2009; 116 Yabe (10.1016/j.jocn.2021.11.029_b0050) 2000; 247 McDougall (10.1016/j.jocn.2021.11.029_b0130) 2018; 130 Kilgore (10.1016/j.jocn.2021.11.029_b0025) 2017; 124 Hornby (10.1016/j.jocn.2021.11.029_b0155) 2016; 87 Ball (10.1016/j.jocn.2021.11.029_b0285) 2011; 258 Mollan (10.1016/j.jocn.2021.11.029_b0020) 2019; 33 Contreras-Martin (10.1016/j.jocn.2021.11.029_b0060) 2015; 30 Welch (10.1016/j.jocn.2021.11.029_b0125) 1960; 83 Altıokka-Uzun (10.1016/j.jocn.2021.11.029_b0145) 2015; 35 10.1016/j.jocn.2021.11.029_b0170 Wall (10.1016/j.jocn.2021.11.029_b0035) 2014; 311 Kalyvas (10.1016/j.jocn.2021.11.029_b0045) 2021; 44 Malm (10.1016/j.jocn.2021.11.029_b0115) 1992; 42 McCarthy (10.1016/j.jocn.2021.11.029_b0280) 1974; 189 Fonseca (10.1016/j.jocn.2021.11.029_b0305) 2014; 98 Mollan (10.1016/j.jocn.2021.11.029_b0030) 2018; 89 Vijay (10.1016/j.jocn.2021.11.029_b0245) 2020; 138 Kupersmith (10.1016/j.jocn.2021.11.029_b0240) 2017; 176 Steinegger (10.1016/j.jocn.2021.11.029_b0265) 2015; 232 Salpietro (10.1016/j.jocn.2021.11.029_b0085) 2013; 162 Friedman (10.1016/j.jocn.2021.11.029_b0005) 2013; 81 Adderley (10.1016/j.jocn.2021.11.029_b0015) 2019; 76 Bothwell (10.1016/j.jocn.2021.11.029_b0100) 2019; 16 Sinclair (10.1016/j.jocn.2021.11.029_b0175) 2010; 95 Rebolleda (10.1016/j.jocn.2021.11.029_b0235) 2009; 50 Gideon (10.1016/j.jocn.2021.11.029_b0120) 1994; 36 10.1016/j.jocn.2021.11.029_b0040 Hermes (10.1016/j.jocn.2021.11.029_b0095) 2020; 95 Digre (10.1016/j.jocn.2021.11.029_b0200) 2015; 84 Klein (10.1016/j.jocn.2021.11.029_b0160) 2013; 38 Wall (10.1016/j.jocn.2021.11.029_b0205) 1991; 114(Pt 1A) Wall (10.1016/j.jocn.2021.11.029_b0210) 1989; 43 Brettschneider (10.1016/j.jocn.2021.11.029_b0190) 2011; 31 Huang‐Link (10.1016/j.jocn.2021.11.029_b0250) 2019; 26 Schoeman (10.1016/j.jocn.2021.11.029_b0290) 1994; 9 Kesler (10.1016/j.jocn.2021.11.029_b0075) 2014; 21 Daniels (10.1016/j.jocn.2021.11.029_b0080) 2007; 143 10.1016/j.jocn.2021.11.029_b0195 10.1016/j.jocn.2021.11.029_b0150 Çelebisoy (10.1016/j.jocn.2021.11.029_b0295) 2007; 116 |
| References_xml | – volume: 36 start-page: 350 year: 1994 end-page: 354 ident: b0120 article-title: Assessment of CSF dynamics and venous flow in the superior sagittal sinus by MRI in idiopathic intracranial hypertension: a preliminary study publication-title: Neuroradiology – volume: 138 start-page: 1264 year: 2020 ident: b0245 article-title: Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension publication-title: JAMA Ophthalmol – volume: 311 start-page: 1641 year: 2014 ident: b0035 article-title: Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial publication-title: JAMA – reference: Kuehn MH, Mishra R, Deonovic BE, Miller KN, McCormack SE, Liu GT, et al. Genetic Survey of Adult-Onset Idiopathic Intracranial Hypertension. J Neuroophthalmol. 2019;39:50-5. – volume: 247 start-page: 474 year: 2000 end-page: 475 ident: b0050 article-title: Incidence of idiopathic intracranial hypertension in Hokkaido, the northernmost island of Japan publication-title: J Neurol – volume: 97 start-page: A6.1 year: 2012 end-page: A6 ident: b0070 article-title: UK surveillance of childhood idiopathic intracranial hypertension (IIH) publication-title: Arch Dis Child – volume: 11 year: 2014 ident: b0105 article-title: Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats publication-title: Fluids Barriers CNS – volume: 596 start-page: 445 year: 2018 end-page: 475 ident: b0110 article-title: Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery publication-title: J Physiol – reference: ISRCTN registry [Internet]. London: BMC. Identifier ISRCTN12678718, IIH Pressure - a new treatment for raised brain pressure in Idiopathic Intracranial Hypertension; Aug 11, 2017 [cited Oct 4, 2020 ]; Available from: – volume: 189 start-page: 194 year: 1974 end-page: 201 ident: b0280 article-title: The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity publication-title: J Pharmacol Exp Ther – volume: 98 start-page: 1360 year: 2014 end-page: 1363 ident: b0305 article-title: Visual outcomes of surgical intervention for pseudotumour cerebri: optic nerve sheath fenestration versus cerebrospinal fluid diversion publication-title: Br J Ophthalmol – volume: 95 start-page: e921 year: 2020 end-page: e929 ident: b0095 article-title: Mortality among patients with idiopathic intracranial hypertension enrolled in the IH Registry publication-title: Neurology – reference: Ball AK, Sinclair AJ, Curnow SJ, Tomlinson JW, Burdon MA, Walker EA, et al. Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance? Clin Endocrinol (Oxf). 2009;70:863-9. – volume: 84 start-page: 2449 year: 2015 end-page: 2456 ident: b0200 article-title: Quality of life in idiopathic intracranial hypertension at diagnosis: IIH Treatment Trial results publication-title: Neurology – volume: 45 start-page: 34 year: 2015 end-page: 39 ident: b0065 article-title: Idiopathic Intracranial Hypertension in the Northwest of Northern Ireland: Epidemiology and Clinical Management publication-title: Neuroepidemiology – volume: 201 start-page: 412 year: 2013 end-page: 418 ident: b0135 article-title: Association of MRI findings and visual outcome in idiopathic intracranial hypertension publication-title: AJR Am J Roentgenol – volume: 232 start-page: 590 year: 2015 end-page: 592 ident: b0265 article-title: Malignant hypertension: clinical manifestations of 7 cases publication-title: Klin Monbl Augenheilkd – volume: 31 start-page: 116 year: 2011 end-page: 121 ident: b0190 article-title: Cerebrospinal fluid markers of idiopathic intracranial hypertension: is the renin-angiotensinogen system involved? publication-title: Cephalalgia – volume: 130 start-page: 999 year: 2018 end-page: 1005 ident: b0130 article-title: Fifty shades of gradients: does the pressure gradient in venous sinus stenting for idiopathic intracranial hypertension matter? A systematic review publication-title: J Neurosurg – volume: 34 start-page: 143 year: 2013 end-page: 145 ident: b0225 article-title: Quantitative analysis of optic nerve damage in idiopathic intracranial hypertension (IIH) at diagnosis publication-title: Neurol Sci – volume: 81 start-page: 1159 year: 2013 end-page: 1165 ident: b0005 article-title: Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children publication-title: Neurology – volume: 76 start-page: 1088 year: 2019 ident: b0015 article-title: Association between Idiopathic Intracranial Hypertension and Risk of Cardiovascular Diseases in Women in the United Kingdom publication-title: JAMA Neurol – volume: 40 start-page: 775 year: 2005 end-page: 777 ident: b0270 article-title: Frequency and amplitude of elevation of cerebrospinal fluid resting pressure by the Valsalva maneuver publication-title: Can J Ophthalmol – volume: 9 start-page: 130 year: 1994 end-page: 134 ident: b0290 article-title: Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series publication-title: J Child Neurol – volume: 95 start-page: 5348 year: 2010 end-page: 5356 ident: b0175 article-title: Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation? publication-title: J Clin Endocrinol Metab – volume: 116 start-page: 322 year: 2007 end-page: 327 ident: b0295 article-title: Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study publication-title: Acta Neurol Scand – volume: 33 start-page: 478 year: 2019 end-page: 485 ident: b0020 article-title: The expanding burden of idiopathic intracranial hypertension publication-title: Eye (Lond) – reference: Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. Bmj. 2010;341:c2701. – volume: 2012 start-page: 1 year: 2012 end-page: 4 ident: b0090 article-title: The prevalence of polycystic ovary syndrome in women with idiopathic intracranial hypertension publication-title: Scientifica (Cairo) – volume: 114(Pt 1A) start-page: 155 year: 1991 end-page: 180 ident: b0205 article-title: Idiopathic intracranial hypertension. A prospective study of 50 patients publication-title: Brain – volume: 1 year: 2007 ident: b0300 article-title: Octreotide: a therapeutic option for idiopathic intracranial hypertension publication-title: Neurol Neurophysiol Neurosci. – reference: Markey K, Mitchell J, Botfield H, Ottridge RS, Matthews T, Krishnan A, et al. 11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial. Brain Communications. 2020;2. – volume: 162 start-page: 1084 year: 2013 ident: b0085 article-title: Pediatric idiopathic intracranial hypertension and extreme childhood obesity: a role for weight gain publication-title: J Pediatr – volume: 35 start-page: 1153 year: 2015 end-page: 1161 ident: b0145 article-title: Oligoclonal bands and increased cytokine levels in idiopathic intracranial hypertension publication-title: Cephalalgia – volume: 35 start-page: 37 year: 1978 end-page: 40 ident: b0220 article-title: The Clinical Significance of Spontaneous Pulsations of the Retinal Vein publication-title: Arch Neurol – volume: 52 start-page: 147 year: 1978 end-page: 150 ident: b0185 article-title: Angiotensin-converting enzyme: presence of high activity in choroid plexus of mammalian brain publication-title: Eur J Pharmacol – volume: 7 start-page: e017426 year: 2017 ident: b0275 article-title: Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol publication-title: BMJ Open – volume: 21 start-page: 1055 year: 2014 end-page: 1059 ident: b0075 article-title: The incidence of idiopathic intracranial hypertension in Israel from 2005 to 2007: results of a nationwide survey publication-title: Eur J Neurol – reference: McHugh JA, D’Antona L, Toma AK, Bremner FD. Spontaneous Venous Pulsations Detected With Infrared Videography. J Neuroophthalmol 2020;40:174-7. – volume: 124 start-page: 697 year: 2017 end-page: 700 ident: b0025 article-title: Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity publication-title: Ophthalmology – volume: 258 start-page: 874 year: 2011 end-page: 881 ident: b0285 article-title: A randomised controlled trial of treatment for idiopathic intracranial hypertension publication-title: J Neurol – volume: 44 start-page: 773 year: 2021 end-page: 792 ident: b0045 article-title: A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH) publication-title: Neurosurg Rev – volume: 116 start-page: 1808 year: 2009 end-page: 1813.e1 ident: b0260 article-title: Functional visual loss in idiopathic intracranial hypertension publication-title: Ophthalmology – volume: 87 start-page: e1.46 year: 2016 end-page: e1 ident: b0155 article-title: The andro-metabolic signature of IIH compared with PCOS and simple obesity publication-title: J Neurol Neurosurg Psychiatry – volume: 124 start-page: 1839 year: 2017 end-page: 1848 ident: b0230 article-title: Accuracy of Diagnostic Imaging Modalities for Classifying Pediatric Eyes as Papilledema Versus Pseudopapilledema publication-title: Ophthalmology – volume: 71 start-page: 693 year: 2014 ident: b0010 article-title: The idiopathic intracranial hypertension treatment trial: clinical profile at baseline publication-title: JAMA Neurol – volume: 83 start-page: 454 year: 1960 end-page: 469 ident: b0125 article-title: The cerebrospinal fluid valves publication-title: Brain – volume: 30 start-page: 106 year: 2015 end-page: 110 ident: b0060 article-title: Idiopathic intracranial hypertension: descriptive analysis in our setting publication-title: Neurologia – volume: 9 year: 2017 ident: b0165 article-title: A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus publication-title: Sci Transl Med – volume: 50 start-page: 5197 year: 2009 ident: b0235 article-title: Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomography publication-title: Invest Ophthalmol Vis Sci – volume: 42 start-page: 851 year: 1992 end-page: 858 ident: b0115 article-title: CSF hydrodynamics in idiopathic intracranial hypertension: a long-term study publication-title: Neurology – volume: 45 start-page: 13 year: 1982 end-page: 18 ident: b0215 article-title: Swelling of the optic nerve head: a staging scheme publication-title: J Neurol Neurosurg Psychiatry – reference: O'Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, et al. A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics. JCI Insight. 2019;4. – volume: 143 start-page: 635 year: 2007 end-page: 641.e1 ident: b0080 article-title: Profiles of obesity, weight gain, and quality of life in idiopathic intracranial hypertension (pseudotumor cerebri) publication-title: Am J Ophthalmol – volume: 38 start-page: 972 year: 2013 end-page: 976 ident: b0160 article-title: Hyperandrogenism is associated with earlier age of onset of idiopathic intracranial hypertension in women publication-title: Curr Eye Res – reference: . – volume: 16 start-page: 9 year: 2019 ident: b0100 article-title: Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases publication-title: Fluids Barriers CNS – volume: 43 start-page: 59 year: 1989 end-page: 66 ident: b0210 article-title: Contrast sensitivity, color vision and perimetry in 100 examinations of patients with optic neuropathies and normal Snellen acuity publication-title: Doc Ophthalmol Proc Ser – volume: 14 start-page: 48 year: 2004 end-page: 54 ident: b0055 article-title: Idiopathic intracranial hypertension (pseudotumor cerebri): descriptive epidemiology, clinical features, and visual outcome in Parma, Italy, 1990 to 1999 publication-title: Eur J Ophthalmol – volume: 176 start-page: 77 year: 2017 end-page: 86 ident: b0240 article-title: The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds publication-title: Am J Ophthalmol – volume: 89 start-page: 1088 year: 2018 end-page: 1100 ident: b0030 article-title: Idiopathic intracranial hypertension: consensus guidelines on management publication-title: J Neurol Neurosurg Psychiatry – volume: 26 start-page: 808 year: 2019 ident: b0250 article-title: Optical coherence tomography represents a sensitive and reliable tool for routine monitoring of idiopathic intracranial hypertension with and without papilledema publication-title: Eur J Neurol – volume: 84 start-page: 2449 issue: 24 year: 2015 ident: 10.1016/j.jocn.2021.11.029_b0200 article-title: Quality of life in idiopathic intracranial hypertension at diagnosis: IIH Treatment Trial results publication-title: Neurology doi: 10.1212/WNL.0000000000001687 – volume: 2012 start-page: 1 year: 2012 ident: 10.1016/j.jocn.2021.11.029_b0090 article-title: The prevalence of polycystic ovary syndrome in women with idiopathic intracranial hypertension publication-title: Scientifica (Cairo) doi: 10.6064/2012/708042 – volume: 45 start-page: 34 issue: 1 year: 2015 ident: 10.1016/j.jocn.2021.11.029_b0065 article-title: Idiopathic Intracranial Hypertension in the Northwest of Northern Ireland: Epidemiology and Clinical Management publication-title: Neuroepidemiology doi: 10.1159/000435919 – volume: 81 start-page: 1159 issue: 13 year: 2013 ident: 10.1016/j.jocn.2021.11.029_b0005 article-title: Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children publication-title: Neurology doi: 10.1212/WNL.0b013e3182a55f17 – volume: 143 start-page: 635 issue: 4 year: 2007 ident: 10.1016/j.jocn.2021.11.029_b0080 article-title: Profiles of obesity, weight gain, and quality of life in idiopathic intracranial hypertension (pseudotumor cerebri) publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2006.12.040 – volume: 45 start-page: 13 issue: 1 year: 1982 ident: 10.1016/j.jocn.2021.11.029_b0215 article-title: Swelling of the optic nerve head: a staging scheme publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.45.1.13 – volume: 52 start-page: 147 issue: 1 year: 1978 ident: 10.1016/j.jocn.2021.11.029_b0185 article-title: Angiotensin-converting enzyme: presence of high activity in choroid plexus of mammalian brain publication-title: Eur J Pharmacol doi: 10.1016/0014-2999(78)90035-3 – volume: 87 start-page: e1.46 issue: 12 year: 2016 ident: 10.1016/j.jocn.2021.11.029_b0155 article-title: The andro-metabolic signature of IIH compared with PCOS and simple obesity publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp-2016-315106.14 – volume: 33 start-page: 478 issue: 3 year: 2019 ident: 10.1016/j.jocn.2021.11.029_b0020 article-title: The expanding burden of idiopathic intracranial hypertension publication-title: Eye (Lond) doi: 10.1038/s41433-018-0238-5 – volume: 35 start-page: 1153 issue: 13 year: 2015 ident: 10.1016/j.jocn.2021.11.029_b0145 article-title: Oligoclonal bands and increased cytokine levels in idiopathic intracranial hypertension publication-title: Cephalalgia doi: 10.1177/0333102415570762 – volume: 14 start-page: 48 issue: 1 year: 2004 ident: 10.1016/j.jocn.2021.11.029_b0055 article-title: Idiopathic intracranial hypertension (pseudotumor cerebri): descriptive epidemiology, clinical features, and visual outcome in Parma, Italy, 1990 to 1999 publication-title: Eur J Ophthalmol doi: 10.1177/112067210401400108 – volume: 9 issue: 404 year: 2017 ident: 10.1016/j.jocn.2021.11.029_b0165 article-title: A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus publication-title: Sci Transl Med doi: 10.1126/scitranslmed.aan0972 – volume: 16 start-page: 9 year: 2019 ident: 10.1016/j.jocn.2021.11.029_b0100 article-title: Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases publication-title: Fluids Barriers CNS doi: 10.1186/s12987-019-0129-6 – ident: 10.1016/j.jocn.2021.11.029_b0140 doi: 10.1111/j.1365-2265.2008.03401.x – ident: 10.1016/j.jocn.2021.11.029_b0195 doi: 10.1097/WNO.0000000000000648 – volume: 31 start-page: 116 issue: 1 year: 2011 ident: 10.1016/j.jocn.2021.11.029_b0190 article-title: Cerebrospinal fluid markers of idiopathic intracranial hypertension: is the renin-angiotensinogen system involved? publication-title: Cephalalgia doi: 10.1177/0333102410375726 – volume: 138 start-page: 1264 issue: 12 year: 2020 ident: 10.1016/j.jocn.2021.11.029_b0245 article-title: Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension publication-title: JAMA Ophthalmol doi: 10.1001/jamaophthalmol.2020.4242 – volume: 7 start-page: e017426 issue: 9 year: 2017 ident: 10.1016/j.jocn.2021.11.029_b0275 article-title: Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol publication-title: BMJ Open doi: 10.1136/bmjopen-2017-017426 – volume: 162 start-page: 1084 year: 2013 ident: 10.1016/j.jocn.2021.11.029_b0085 article-title: Pediatric idiopathic intracranial hypertension and extreme childhood obesity: a role for weight gain publication-title: J Pediatr doi: 10.1016/j.jpeds.2013.01.048 – volume: 95 start-page: e921 issue: 7 year: 2020 ident: 10.1016/j.jocn.2021.11.029_b0095 article-title: Mortality among patients with idiopathic intracranial hypertension enrolled in the IH Registry publication-title: Neurology doi: 10.1212/WNL.0000000000009312 – volume: 42 start-page: 851 issue: 4 year: 1992 ident: 10.1016/j.jocn.2021.11.029_b0115 article-title: CSF hydrodynamics in idiopathic intracranial hypertension: a long-term study publication-title: Neurology doi: 10.1212/WNL.42.4.851 – volume: 116 start-page: 1808 issue: 9 year: 2009 ident: 10.1016/j.jocn.2021.11.029_b0260 article-title: Functional visual loss in idiopathic intracranial hypertension publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.03.056 – volume: 1 year: 2007 ident: 10.1016/j.jocn.2021.11.029_b0300 article-title: Octreotide: a therapeutic option for idiopathic intracranial hypertension publication-title: Neurol Neurophysiol Neurosci. – volume: 97 start-page: A6.1 issue: Suppl 1 year: 2012 ident: 10.1016/j.jocn.2021.11.029_b0070 article-title: UK surveillance of childhood idiopathic intracranial hypertension (IIH) publication-title: Arch Dis Child doi: 10.1136/archdischild-2012-301885.14 – volume: 258 start-page: 874 issue: 5 year: 2011 ident: 10.1016/j.jocn.2021.11.029_b0285 article-title: A randomised controlled trial of treatment for idiopathic intracranial hypertension publication-title: J Neurol doi: 10.1007/s00415-010-5861-4 – volume: 98 start-page: 1360 issue: 10 year: 2014 ident: 10.1016/j.jocn.2021.11.029_b0305 article-title: Visual outcomes of surgical intervention for pseudotumour cerebri: optic nerve sheath fenestration versus cerebrospinal fluid diversion publication-title: Br J Ophthalmol doi: 10.1136/bjophthalmol-2014-304953 – volume: 89 start-page: 1088 issue: 10 year: 2018 ident: 10.1016/j.jocn.2021.11.029_b0030 article-title: Idiopathic intracranial hypertension: consensus guidelines on management publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp-2017-317440 – volume: 83 start-page: 454 issue: 3 year: 1960 ident: 10.1016/j.jocn.2021.11.029_b0125 article-title: The cerebrospinal fluid valves publication-title: Brain doi: 10.1093/brain/83.3.454 – volume: 50 start-page: 5197 issue: 11 year: 2009 ident: 10.1016/j.jocn.2021.11.029_b0235 article-title: Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomography publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-2528 – ident: 10.1016/j.jocn.2021.11.029_b0040 doi: 10.1136/bmj.c2701 – volume: 201 start-page: 412 issue: 2 year: 2013 ident: 10.1016/j.jocn.2021.11.029_b0135 article-title: Association of MRI findings and visual outcome in idiopathic intracranial hypertension publication-title: AJR Am J Roentgenol doi: 10.2214/AJR.12.9638 – volume: 34 start-page: 143 issue: S1 year: 2013 ident: 10.1016/j.jocn.2021.11.029_b0225 article-title: Quantitative analysis of optic nerve damage in idiopathic intracranial hypertension (IIH) at diagnosis publication-title: Neurol Sci doi: 10.1007/s10072-013-1373-1 – volume: 21 start-page: 1055 issue: 8 year: 2014 ident: 10.1016/j.jocn.2021.11.029_b0075 article-title: The incidence of idiopathic intracranial hypertension in Israel from 2005 to 2007: results of a nationwide survey publication-title: Eur J Neurol doi: 10.1111/ene.12442 – volume: 130 start-page: 999 year: 2018 ident: 10.1016/j.jocn.2021.11.029_b0130 article-title: Fifty shades of gradients: does the pressure gradient in venous sinus stenting for idiopathic intracranial hypertension matter? A systematic review publication-title: J Neurosurg doi: 10.3171/2017.8.JNS17459 – volume: 26 start-page: 808 issue: 5 year: 2019 ident: 10.1016/j.jocn.2021.11.029_b0250 article-title: Optical coherence tomography represents a sensitive and reliable tool for routine monitoring of idiopathic intracranial hypertension with and without papilledema publication-title: Eur J Neurol doi: 10.1111/ene.13893 – volume: 38 start-page: 972 issue: 9 year: 2013 ident: 10.1016/j.jocn.2021.11.029_b0160 article-title: Hyperandrogenism is associated with earlier age of onset of idiopathic intracranial hypertension in women publication-title: Curr Eye Res doi: 10.3109/02713683.2013.799214 – volume: 189 start-page: 194 year: 1974 ident: 10.1016/j.jocn.2021.11.029_b0280 article-title: The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity publication-title: J Pharmacol Exp Ther doi: 10.1016/S0022-3565(25)29822-6 – ident: 10.1016/j.jocn.2021.11.029_b0170 – ident: 10.1016/j.jocn.2021.11.029_b0255 doi: 10.1097/WNO.0000000000000815 – volume: 311 start-page: 1641 issue: 16 year: 2014 ident: 10.1016/j.jocn.2021.11.029_b0035 article-title: Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial publication-title: JAMA doi: 10.1001/jama.2014.3312 – volume: 95 start-page: 5348 year: 2010 ident: 10.1016/j.jocn.2021.11.029_b0175 article-title: Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation? publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2010-0729 – volume: 30 start-page: 106 year: 2015 ident: 10.1016/j.jocn.2021.11.029_b0060 article-title: Idiopathic intracranial hypertension: descriptive analysis in our setting publication-title: Neurologia doi: 10.1016/j.nrl.2013.08.009 – volume: 36 start-page: 350 issue: 5 year: 1994 ident: 10.1016/j.jocn.2021.11.029_b0120 article-title: Assessment of CSF dynamics and venous flow in the superior sagittal sinus by MRI in idiopathic intracranial hypertension: a preliminary study publication-title: Neuroradiology doi: 10.1007/BF00612116 – ident: 10.1016/j.jocn.2021.11.029_b0180 doi: 10.1093/braincomms/fcz050 – volume: 114(Pt 1A) start-page: 155 year: 1991 ident: 10.1016/j.jocn.2021.11.029_b0205 article-title: Idiopathic intracranial hypertension. A prospective study of 50 patients publication-title: Brain – ident: 10.1016/j.jocn.2021.11.029_b0150 doi: 10.1172/jci.insight.125348 – volume: 76 start-page: 1088 issue: 9 year: 2019 ident: 10.1016/j.jocn.2021.11.029_b0015 article-title: Association between Idiopathic Intracranial Hypertension and Risk of Cardiovascular Diseases in Women in the United Kingdom publication-title: JAMA Neurol doi: 10.1001/jamaneurol.2019.1812 – volume: 44 start-page: 773 issue: 2 year: 2021 ident: 10.1016/j.jocn.2021.11.029_b0045 article-title: A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH) publication-title: Neurosurg Rev doi: 10.1007/s10143-020-01288-1 – volume: 9 start-page: 130 issue: 2 year: 1994 ident: 10.1016/j.jocn.2021.11.029_b0290 article-title: Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series publication-title: J Child Neurol doi: 10.1177/088307389400900205 – volume: 35 start-page: 37 issue: 1 year: 1978 ident: 10.1016/j.jocn.2021.11.029_b0220 article-title: The Clinical Significance of Spontaneous Pulsations of the Retinal Vein publication-title: Arch Neurol doi: 10.1001/archneur.1978.00500250041009 – volume: 40 start-page: 775 issue: 6 year: 2005 ident: 10.1016/j.jocn.2021.11.029_b0270 article-title: Frequency and amplitude of elevation of cerebrospinal fluid resting pressure by the Valsalva maneuver publication-title: Can J Ophthalmol doi: 10.1016/S0008-4182(05)80100-0 – volume: 124 start-page: 1839 issue: 12 year: 2017 ident: 10.1016/j.jocn.2021.11.029_b0230 article-title: Accuracy of Diagnostic Imaging Modalities for Classifying Pediatric Eyes as Papilledema Versus Pseudopapilledema publication-title: Ophthalmology doi: 10.1016/j.ophtha.2017.06.016 – volume: 232 start-page: 590 issue: 04 year: 2015 ident: 10.1016/j.jocn.2021.11.029_b0265 article-title: Malignant hypertension: clinical manifestations of 7 cases publication-title: Klin Monbl Augenheilkd doi: 10.1055/s-0034-1396333 – volume: 116 start-page: 322 issue: 5 year: 2007 ident: 10.1016/j.jocn.2021.11.029_b0295 article-title: Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study publication-title: Acta Neurol Scand doi: 10.1111/j.1600-0404.2007.00905.x – volume: 124 start-page: 697 issue: 5 year: 2017 ident: 10.1016/j.jocn.2021.11.029_b0025 article-title: Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity publication-title: Ophthalmology doi: 10.1016/j.ophtha.2017.01.006 – volume: 71 start-page: 693 issue: 6 year: 2014 ident: 10.1016/j.jocn.2021.11.029_b0010 article-title: The idiopathic intracranial hypertension treatment trial: clinical profile at baseline publication-title: JAMA Neurol doi: 10.1001/jamaneurol.2014.133 – volume: 11 issue: 1 year: 2014 ident: 10.1016/j.jocn.2021.11.029_b0105 article-title: Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats publication-title: Fluids Barriers CNS doi: 10.1186/2045-8118-11-12 – volume: 43 start-page: 59 year: 1989 ident: 10.1016/j.jocn.2021.11.029_b0210 article-title: Contrast sensitivity, color vision and perimetry in 100 examinations of patients with optic neuropathies and normal Snellen acuity publication-title: Doc Ophthalmol Proc Ser – volume: 596 start-page: 445 issue: 3 year: 2018 ident: 10.1016/j.jocn.2021.11.029_b0110 article-title: Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery publication-title: J Physiol doi: 10.1113/JP275105 – volume: 247 start-page: 474 year: 2000 ident: 10.1016/j.jocn.2021.11.029_b0050 article-title: Incidence of idiopathic intracranial hypertension in Hokkaido, the northernmost island of Japan publication-title: J Neurol doi: 10.1007/s004150070182 – volume: 176 start-page: 77 year: 2017 ident: 10.1016/j.jocn.2021.11.029_b0240 article-title: The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2016.12.017 |
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| Snippet | •The population burden of IIH is projected to rise with increasing rates of obesity.•Recent studies highlight the pathogenic role of metabolic and hormonal... Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure, manifested by papilledema and radiological findings, in the... |
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| SubjectTerms | Cerebrospinal fluid Complications Diagnosis Female Humans Intracranial Hypertension Prospective Studies Pseudotumor cerebri Pseudotumor Cerebri - diagnosis Pseudotumor Cerebri - therapy Quality of Life Stents Therapy Venous sinus |
| Title | Idiopathic intracranial hypertension: Pathophysiology, diagnosis and management |
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