Intestinal intussusception as a metastatic presentation of Acral Melanoma – Case report

•Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure.•Intussusception is an extraordinarily rare clinical entity in adults and the most common cause is a neoplasm.•Think cancer in an adult intussusception. Acral melanoma is a clinical subtype of melan...

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Veröffentlicht in:Current problems in cancer. Case reports Jg. 19; S. 100385
Hauptverfasser: Martínez Zamorano, Monserrat, Flores Solares, Elizabeth, Prado Salcedo, Tatiana Andrea, Aguilera de Alba, Karen Sofía, Sanchez Martínez, María de Lourdes
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Elsevier Inc 01.09.2025
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ISSN:2666-6219, 2666-6219
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Abstract •Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure.•Intussusception is an extraordinarily rare clinical entity in adults and the most common cause is a neoplasm.•Think cancer in an adult intussusception. Acral melanoma is a clinical subtype of melanoma that occurs on surfaces that do not develop hair, frequently metastasizes, and presents significant recurrence. Intestinal metastasis occurs in 0.3 % of cases and may exceptionally manifest as intussusception. A young adult man diagnosed with clinical stage IV acral melanoma came to the emergency room with abdominal pain, nausea, and hematemesis. An abdominal tomography was performed with data of intestinal intussusception with subsequent emergency laparotomy showing ileo-ileal invagination secondary to a hyperpigmented tumor lesion. Acral melanoma rarely develops intestinal metastases and it is even rarer to cause intussusception compared to other types of melanoma. Imaging studies are useful for diagnosis and emergency laparotomy is the procedure of choice. Surgical findings should be confirmed by histopathological study and individualized treatment should be offered. Intestinal intussusception is a rare surgical emergency in adults; malignant etiology should be suspected from the patient's clinical history.
AbstractList •Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure.•Intussusception is an extraordinarily rare clinical entity in adults and the most common cause is a neoplasm.•Think cancer in an adult intussusception. Acral melanoma is a clinical subtype of melanoma that occurs on surfaces that do not develop hair, frequently metastasizes, and presents significant recurrence. Intestinal metastasis occurs in 0.3 % of cases and may exceptionally manifest as intussusception. A young adult man diagnosed with clinical stage IV acral melanoma came to the emergency room with abdominal pain, nausea, and hematemesis. An abdominal tomography was performed with data of intestinal intussusception with subsequent emergency laparotomy showing ileo-ileal invagination secondary to a hyperpigmented tumor lesion. Acral melanoma rarely develops intestinal metastases and it is even rarer to cause intussusception compared to other types of melanoma. Imaging studies are useful for diagnosis and emergency laparotomy is the procedure of choice. Surgical findings should be confirmed by histopathological study and individualized treatment should be offered. Intestinal intussusception is a rare surgical emergency in adults; malignant etiology should be suspected from the patient's clinical history.
Introduction: Acral melanoma is a clinical subtype of melanoma that occurs on surfaces that do not develop hair, frequently metastasizes, and presents significant recurrence. Intestinal metastasis occurs in 0.3 % of cases and may exceptionally manifest as intussusception. Presentation of case: A young adult man diagnosed with clinical stage IV acral melanoma came to the emergency room with abdominal pain, nausea, and hematemesis. An abdominal tomography was performed with data of intestinal intussusception with subsequent emergency laparotomy showing ileo-ileal invagination secondary to a hyperpigmented tumor lesion. Discussion: Acral melanoma rarely develops intestinal metastases and it is even rarer to cause intussusception compared to other types of melanoma. Imaging studies are useful for diagnosis and emergency laparotomy is the procedure of choice. Surgical findings should be confirmed by histopathological study and individualized treatment should be offered. Conclusion: Intestinal intussusception is a rare surgical emergency in adults; malignant etiology should be suspected from the patient's clinical history.
Highlights•Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure. •Intussusception is an extraordinarily rare clinical entity in adults and the most common cause is a neoplasm. •Think cancer in an adult intussusception.
ArticleNumber 100385
Author Sanchez Martínez, María de Lourdes
Flores Solares, Elizabeth
Aguilera de Alba, Karen Sofía
Martínez Zamorano, Monserrat
Prado Salcedo, Tatiana Andrea
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  surname: Martínez Zamorano
  fullname: Martínez Zamorano, Monserrat
  email: monse.mtz.z@gmail.comx
  organization: Department of Digestive and Musculoskeletal Tract / General Surgery Service / Hospital Regional de Alta Especialidad del Bajío IMSS- Bienestar, León, Guanajuato, Mexico
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  givenname: Elizabeth
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  surname: Flores Solares
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  givenname: Tatiana Andrea
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  surname: Prado Salcedo
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  givenname: María de Lourdes
  orcidid: 0009-0003-6381-3703
  surname: Sanchez Martínez
  fullname: Sanchez Martínez, María de Lourdes
  organization: Department of Pathological Anatomy / Hospital Regional de Alta Especialidad del Bajío IMSS- Bienestar, León, Guanajuato, Mexico
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Keywords Metastasis of the neoplasm
Gastrointestinal metastasis
Intussusception
Melanoma
Language English
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Snippet •Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure.•Intussusception is an extraordinarily rare clinical entity in...
Highlights•Acral melanoma occurs on hairless skin, it isn't associated with ultraviolet radiation exposure. •Intussusception is an extraordinarily rare...
Introduction: Acral melanoma is a clinical subtype of melanoma that occurs on surfaces that do not develop hair, frequently metastasizes, and presents...
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elsevier
SourceType Open Website
Index Database
Publisher
StartPage 100385
SubjectTerms Gastrointestinal metastasis
Hematology, Oncology, and Palliative Medicine
Intussusception
Melanoma
Metastasis of the neoplasm
Title Intestinal intussusception as a metastatic presentation of Acral Melanoma – Case report
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