Pharmacological Properties of Sulfonamide Derivatives, New Inhibitors of Carbonic Anhydrase

Selective blocking of individual isoforms of carbonic anhydrase (CA) is now one of the main directions in the development of its inhibitors. The new 1,2,4-oxadiazole-containing sulfonamides B12 and B13 predominantly block CA II and CA IX. The study of acute toxicity of B12 and B13 showed their safet...

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 175; no. 2; pp. 205 - 209
Main Authors:	Khokhlov, A. L., Shetnev, A. A., Korsakov, M. K., Fedorov, V. N., Tyushina, A. N., Volkhin, N. N., Vdovichenko, V. P.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.06.2023 Springer Springer Nature B.V
Subjects:	Acute toxicity Analysis Animals Antibiotics Antidepressants Antigens, Neoplasm Biomedical and Life Sciences Biomedicine Brinzolamide Carbon dioxide Carbonic Anhydrase Inhibitors - pharmacology Carbonic anhydrases Carbonic Anhydrases - metabolism Cell Biology Drugs Enzymes Glaucoma Internal Medicine Isoforms Laboratory animals Laboratory Medicine Medical practices Pathology Pedagogy Pharmaceuticals Physiology Protein Isoforms Rabbits Respiration Structure-Activity Relationship Sulfonamides Sulfonamides - pharmacology Toxicology carbonic anhydrases sulfonamides carbonic anhydrase inhibitors intraocular pressure
ISSN:	0007-4888, 1573-8221, 1573-8221
Online Access:	Get full text
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