Selective cytotoxicity of intense nanosecond-duration electric pulses in mammalian cells

Nanosecond electric pulses (EP) disrupt cell membrane and organelles and cause cell death in a manner different from the conventional irreversible electroporation. We explored the cytotoxic effect of 10-ns EP (quantitation, mechanisms, efficiency, and specificity) in comparison with 300-ns, 1.8- and...

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Veröffentlicht in:	Biochimica et biophysica acta Jg. 1800; H. 11; S. 1210 - 1219
Hauptverfasser:	Ibey, Bennett L., Pakhomov, Andrei G., Gregory, Betsy W., Khorokhorina, Vera A., Roth, Caleb C., Rassokhin, Mikhail A., Bernhard, Joshua A., Wilmink, Gerald J., Pakhomova, Olga N.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands 01.11.2010
Schlagworte:	Apoptosis - radiation effects Cell Membrane - metabolism Cell Membrane - pathology Cell Membrane - radiation effects Cell Membrane Permeability - radiation effects DNA Damage Electromagnetic Fields Electroporation Flow Cytometry Humans Jurkat Cells Organelles - metabolism Organelles - pathology Organelles - radiation effects Phosphatidylserines - metabolism U937 Cells
ISSN:	0304-4165, 0006-3002
Online-Zugang:	Volltext
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