Co-existence of EGFR T790M-acquired lung adenocarcinoma and transformation into small-cell carcinoma in different organs after osimertinib treatment. A case report

•This case reports co-existing T790M-positive adenocarcinoma and T790M-negative small-cell carcinoma transformation in different organs after osimertinib treatment.•Cytology and biopsy findings highlighted the importance of re-biopsy in identifying resistance mechanisms in EGFR-mutated lung cancer.•...

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Bibliographic Details

Published in:	Current problems in cancer. Case reports Vol. 19; p. 100376
Main Authors:	Takeda, Masahide, Asano, Mariko, Sakamoto, Sho, Izumiya, Yuka, Okuda, Yuji, Sato, Kazuhiro, Nakayama, Katsutoshi
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01.09.2025 Elsevier
Subjects:	Hematology, Oncology, and Palliative Medicine Lung adenocarcinoma osimertinib transformation into small-cell carcinoma transformation into small-cell carcinoma osimertinib Lung adenocarcinoma
ISSN:	2666-6219, 2666-6219
Online Access:	Get full text
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