Digital droplet PCR versus quantitative PCR for lipoprotein (a) kringle IV type 2 repeat polymorphism genetic characterization

Background Lipoprotein(a) [Lp(a)] level variability, related to atherothrombotic risk increase, is mainly attributed to LPA gene, encoding apolipoprotein(a), with kringle IV type 2 (KIV2) copy number variation (CNV) acting as the primary genetic determinant. Genetic characterization of Lp(a) is in c...

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Vydáno v:	Journal of clinical laboratory analysis Ročník 38; číslo 5; s. e24998 - n/a
Hlavní autoři:	Barbieri, Giulia, Cassioli, Giulia, Kura, Ada, Orsi, Rebecca, Magi, Alberto, Berteotti, Martina, Scaturro, Giusi Maria, Lotti, Elena, Gori, Anna Maria, Marcucci, Rossella, Giusti, Betti, Sticchi, Elena
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States John Wiley & Sons, Inc 01.03.2024
Témata:	Apolipoproteins atherothrombotic risk Cardiovascular diseases Cholesterol Copy number Correlation analysis digital droplet PCR Enzymes Gene polymorphism High density lipoprotein kringle IV type 2 Laboratories lipoprotein (a) Lipoproteins Methods Plasma Plasma levels Polymerase chain reaction Polymorphism Proteins Quantitative analysis quantitative real‐time PCR Software Statistical analysis United States > US Germany quantitative real‐time PCR kringle IV type 2 digital droplet PCR atherothrombotic risk lipoprotein (a)
ISSN:	0887-8013, 1098-2825, 1098-2825
On-line přístup:	Získat plný text
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