Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020

infection is one of the most common infectious diseases worldwide. Although the prevalence of is gradually decreasing, approximately half of the world's population still becomes infected with this disease. is responsible for substantial gastrointestinal morbidity worldwide, with a high disease...

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Veröffentlicht in:Gut and liver Jg. 15; H. 2; S. 168 - 195
Hauptverfasser: Jung, Hye-Kyung, Kang, Seung Joo, Lee, Yong Chan, Yang, Hyo-Joon, Park, Seon-Young, Shin, Cheol Min, Kim, Sung Eun, Lim, Hyun Chul, Kim, Jie-Hyun, Nam, Su Youn, Shin, Woon Geon, Park, Jae Myung, Choi, Il Ju, Kim, Jae Gyu, Choi, Miyoung
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Korea (South) Editorial Office of Gut and Liver 15.03.2021
Gastroenterology Council for Gut and Liver
거트앤리버 소화기연관학회협의회
Schlagworte:
Clarithromycin
Duodenal Ulcer
guidelines
Helicobacter Infections - drug therapy
Helicobacter Infections - epidemiology
Helicobacter pylori
Humans
meta-analysis
microbial sensitivity tests
Randomized Controlled Trials as Topic
Republic of Korea
Review
treatment
내과학
Republic of Korea
Microbial sensitivity tests
Treatment
Helicobacter pylori
Guidelines
Meta-analysis
ISSN:1976-2283, 2005-1212, 2005-1212
Online-Zugang:Volltext
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Zusammenfassung:infection is one of the most common infectious diseases worldwide. Although the prevalence of is gradually decreasing, approximately half of the world's population still becomes infected with this disease. is responsible for substantial gastrointestinal morbidity worldwide, with a high disease burden. It is the most common cause of gastric and duodenal ulcers and gastric cancer. Since the revision of the clinical practice guidelines in 2013 in Korea, the eradication rate of has gradually decreased with the use of a clarithromycin-based triple therapy for 7 days. According to a nationwide randomized controlled study conducted by the Korean College of and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance, especially from clarithromycin. The clinical practice guidelines for the treatment of were updated according to evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after an expert consensus on three recommendations regarding the indication for treatment and eight recommendations for the treatment itself. These guidelines were designed to provide clinical evidence for the treatment (including primary care treatment) of infection to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards and will be revised if more evidence emerges in the future.
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ObjectType-Feature-2
ObjectType-Review-3
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Hye-Kyung Jung and Seung Joo Kang contributed equally to this work as first authors.
ISSN:1976-2283
2005-1212
2005-1212
DOI:10.5009/gnl20288