MLKL: Functions beyond serving as the Executioner of Necroptosis

Recently, necroptosis, as a programmed cell death pathway, has drawn much attention as it has been implicated in multiple pathologies, especially in the field of inflammatory diseases. Pseudokinase mixed lineage kinase domain-like protein (MLKL) serves as a terminal-known obligate effector in the pr...

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Bibliographic Details
Published in:	Theranostics Vol. 11; no. 10; pp. 4759 - 4769
Main Authors:	Zhan, Chaoning, Huang, Minchun, Yang, Xiaojun, Hou, Jin
Format:	Journal Article
Language:	English
Published:	Australia Ivyspring International Publisher Pty Ltd 01.01.2021 Ivyspring International Publisher
Subjects:	Apoptosis Heat shock proteins Homeostasis Kinases Lymphoma Pathogens Phosphorylation Plasma Regulation Review Tumor necrosis factor-TNF inhibitors therapeutic target MLKL structure necroptosis
ISSN:	1838-7640, 1838-7640
Online Access:	Get full text
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