Aseptic loosening of femoral components – Materials engineering and design considerations

► Aseptic loosening of femoral component is associated with the deficiencies in engineering design. ► The main leading causes of loosening are wear behavior, bioactivity and mechanical properties. ► Functionally graded biomaterials have the potential to reduce the occurrence of leading causes. Asept...

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Bibliographic Details
Published in:Materials in engineering Vol. 44; pp. 155 - 163
Main Authors: Bahraminasab, Marjan, Sahari, B.B., Edwards, K.L., Farahmand, Farzam, Arumugam, Manohar
Format: Journal Article
Language:English
Published: Elsevier Ltd 01.02.2013
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ISSN:0261-3069
Online Access:Get full text
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Summary:► Aseptic loosening of femoral component is associated with the deficiencies in engineering design. ► The main leading causes of loosening are wear behavior, bioactivity and mechanical properties. ► Functionally graded biomaterials have the potential to reduce the occurrence of leading causes. Aseptic loosening is one of the main reasons for the revision of a total knee replacement (TKR). The design of the key component of a TKR, the femoral component, is particularly problematic because its failure can be the result of different causes. This makes the development of new biomaterials for use in the femoral component a challenging task. This paper focuses on the engineering design aspects in order to understand the limitations of current materials and design deficiencies. The paper describes the introduction of a new biomaterial for a femoral component and justifies the recommendation to use multi-functional materials as a possible solution to aseptic loosening. The potential advantages of applying functionally graded biomaterials (FGBMs) in prosthetic femur are explained by reducing the leading causes of failure including wear, micro-motion and stress-shielding effect. The ideas presented in this paper can be used as the basis for further research on the feasibility and advantages of applying FGBM in other superior implant designs.
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ISSN:0261-3069
DOI:10.1016/j.matdes.2012.07.066