C3 ‐dependent effector functions of complement

C3 is the central effector molecule of the complement system, mediating its multiple functions through different binding sites and their corresponding receptors. We will introduce the C3 forms (native C3, C3 [H 2 O], and intracellular C3), the C3 fragments C3a, C3b, iC3b, and C3dg/C3d, and the C3 ex...

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Bibliographic Details
Published in:	Immunological reviews Vol. 313; no. 1; pp. 120 - 138
Main Authors:	Zarantonello, Alessandra, Revel, Margot, Grunenwald, Anne, Roumenina, Lubka T.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.01.2023 Wiley John Wiley and Sons Inc
Subjects:	Anaphylatoxins Binding Sites Biochemistry, Molecular Biology Biological activity Cancer Cell activation Complement Complement Activation Complement C3 - analysis Complement C3 - metabolism Complement C3b - metabolism Complement component C3 Complement component C3b Complement component C3d Complement receptors Fragments Humans Immunology Innate immunity Invited Review Invited Reviews Life Sciences Molecular structure Opsonins Receptors Receptors, Complement - analysis Structural Biology cancer autoimmunity inflammation anaphylatoxin opsonin complement C3
ISSN:	0105-2896, 1600-065X, 1600-065X
Online Access:	Get full text
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