ERS International Congress 2021: highlights from the Paediatric Assembly

In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiolo...

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Published in:ERJ open research Vol. 8; no. 2; p. 643
Main Authors: Ardura-Garcia, Cristina, Abellan, Alicia, Cuevas-Ocaña, Sara, Freitag, Nadine, Lam, Yin Ting, Makrinioti, Heidi, Slaats, Monique, Storti, Matteo, Williams, Emma E., Dassios, Theodore, Duijts, Liesbeth, Ersu, Refika H., Fustik, Stojka, Morty, Rory E., Proesmans, Marijke, Schramm, Dirk, Saglani, Sejal, Moeller, Alexander, Pijnenburg, Marielle W.
Format: Journal Article
Language:English
Published: England European Respiratory Society 01.04.2022
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Congress Highlights
ISSN:2312-0541, 2312-0541
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Abstract In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets.
AbstractList In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets. Highlights from the Paediatrics Assembly at #ERSCongress 2021 https://bit.ly/3FaFgNt
In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets.
In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets.In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets.
Author Schramm, Dirk
Abellan, Alicia
Slaats, Monique
Freitag, Nadine
Lam, Yin Ting
Storti, Matteo
Moeller, Alexander
Cuevas-Ocaña, Sara
Duijts, Liesbeth
Saglani, Sejal
Dassios, Theodore
Morty, Rory E.
Williams, Emma E.
Ardura-Garcia, Cristina
Fustik, Stojka
Pijnenburg, Marielle W.
Ersu, Refika H.
Makrinioti, Heidi
Proesmans, Marijke
AuthorAffiliation 6 Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK
7 Dept of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
17 Dept of Translational Pulmonology and the Translational Lung Research Center Heidelberg, University Hospital Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg, Germany
14 Division of Respirology, University of Ottawa Children's Hospital of Eastern Ontario, Ottawa, Canada
8 West Middlesex University Hospital, Chelsea and Westminster Foundation Trust, London, UK
15 University Children's Hospital, Skopje, North Macedonia
10 Dept of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy
12 Neonatal Intensive Care Centre, King's College Hospital NHS Foundation Trust, London, UK
5 Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid
AuthorAffiliation_xml – name: 16 Dept of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
– name: 13 Division of Neonatology, Dept of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands
– name: 19 National Heart and Lung Institute, Imperial College London, London, UK
– name: 3 Universitat Pompeu Fabra, Barcelona, Spain
– name: 15 University Children's Hospital, Skopje, North Macedonia
– name: 20 Division of Paediatric Pulmonology, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland
– name: 12 Neonatal Intensive Care Centre, King's College Hospital NHS Foundation Trust, London, UK
– name: 17 Dept of Translational Pulmonology and the Translational Lung Research Center Heidelberg, University Hospital Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg, Germany
– name: 18 Division Woman and Child, Dept of Paediatrics, University Hospitals Leuven, Leuven, Belgium
– name: 1 Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
– name: 6 Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK
– name: 9 Dept of Paediatrics, Division of Paediatric Respiratory Medicine and Allergology, Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands
– name: 10 Dept of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy
– name: 14 Division of Respirology, University of Ottawa Children's Hospital of Eastern Ontario, Ottawa, Canada
– name: 2 ISGlobal, Barcelona, Spain
– name: 11 Dept of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK
– name: 5 Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain
– name: 7 Dept of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
– name: 4 Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, Barcelona, Spain
– name: 8 West Middlesex University Hospital, Chelsea and Westminster Foundation Trust, London, UK
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  givenname: Marielle W.
  surname: Pijnenburg
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2024101711281320000_8.2.00643-2021.4
2024101711281320000_8.2.00643-2021.38
2024101711281320000_8.2.00643-2021.46
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2024101711281320000_8.2.00643-2021.40
2024101711281320000_8.2.00643-2021.84
2024101711281320000_8.2.00643-2021.83
2024101711281320000_8.2.00643-2021.42
2024101711281320000_8.2.00643-2021.41
2024101711281320000_8.2.00643-2021.85
2024101711281320000_8.2.00643-2021.80
2024101711281320000_8.2.00643-2021.82
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2024101711281320000_8.2.00643-2021.11
2024101711281320000_8.2.00643-2021.55
2024101711281320000_8.2.00643-2021.54
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