PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis

Despite growing importance of long non-coding RNAs (lncRNAs) in normal physiological and disease conditions, our knowledge of RA-related lncRNAs remains limited. Therefore, we aimed to identify lncRNA signatures that have prognostic values in RA. There was a notably high expression level of Hotair i...

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Bibliographic Details
Published in:	Clinical and experimental medicine Vol. 15; no. 1; pp. 121 - 126
Main Authors:	Song, Jinsoo, Kim, Dongkyun, Han, Jiyeon, Kim, Yunha, Lee, Myeungsu, Jin, Eun-Jung
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.02.2015 Springer Nature B.V
Subjects:	Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Biomarkers Biomarkers - metabolism Chemotaxis Exosomes - chemistry Exosomes - metabolism Gene Expression Hematology Humans Internal Medicine Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - pathology Macrophages - metabolism Macrophages - pathology Matrix Metalloproteinase 13 - genetics Matrix Metalloproteinase 13 - metabolism Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - metabolism Medicine Medicine & Public Health Oncology Osteoclasts - metabolism Osteoclasts - pathology Primary Cell Culture Rheumatoid arthritis Ribonucleic acid RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Short Communication Synovial Fluid - chemistry Synovial Fluid - metabolism Synovial Membrane - metabolism Synovial Membrane - pathology U937 Cells LncRNA Matrix metalloprotease Hotair BMCS Exosome Rheumatoid arthritis
ISSN:	1591-9528, 1591-8890, 1591-9528
Online Access:	Get full text
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