Cangrelor, Tirofiban, and Chewed or Standard Prasugrel Regimens in Patients With ST-Segment-Elevation Myocardial Infarction: Primary Results of the FABOLUS-FASTER Trial

Standard administration of newer oral P2Y inhibitors, including prasugrel or ticagrelor, provides suboptimal early inhibition of platelet aggregation (IPA) in patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention. We aimed to investigate the e...

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Bibliographic Details
Published in:	Circulation (New York, N.Y.) Vol. 142; no. 5; p. 441
Main Authors:	Gargiulo, Giuseppe, Esposito, Giovanni, Avvedimento, Marisa, Nagler, Michael, Minuz, Pietro, Campo, Gianluca, Gragnano, Felice, Manavifar, Negar, Piccolo, Raffaele, Tebaldi, Matteo, Cirillo, Plinio, Hunziker, Lukas, Vranckx, Pascal, Leonardi, Sergio, Heg, Dik, Windecker, Stephan, Valgimigli, Marco
Format:	Journal Article
Language:	English
Published:	United States 04.08.2020
Subjects:	Adenosine Diphosphate - pharmacology Adenosine Monophosphate - administration & dosage Adenosine Monophosphate - analogs & derivatives Adenosine Monophosphate - blood Adenosine Monophosphate - pharmacology Adenosine Monophosphate - therapeutic use Administration, Oral Aged Aged, 80 and over Area Under Curve Aspirin - therapeutic use Cardiac Catheterization Comorbidity Female Heart - physiopathology Humans Infusions, Intravenous Male Mastication Middle Aged Percutaneous Coronary Intervention Platelet Aggregation - drug effects Polypharmacy Prasugrel Hydrochloride - administration & dosage Prasugrel Hydrochloride - blood Prasugrel Hydrochloride - pharmacology Prasugrel Hydrochloride - therapeutic use Proportional Hazards Models Purinergic P2Y Receptor Antagonists - administration & dosage Purinergic P2Y Receptor Antagonists - blood Purinergic P2Y Receptor Antagonists - pharmacology Purinergic P2Y Receptor Antagonists - therapeutic use ST Elevation Myocardial Infarction - drug therapy ST Elevation Myocardial Infarction - therapy Tablets Tirofiban - administration & dosage Tirofiban - blood Tirofiban - pharmacology Tirofiban - therapeutic use Treatment Outcome percutaneous coronary intervention cangrelor prasugrel hydrochloride tirofiban platelet aggregation
ISSN:	1524-4539, 1524-4539
Online Access:	Get more information
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