Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need

To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant mor...

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Vydané v:	Journal of stroke Ročník 19; číslo 1; s. 50 - 60
Hlavní autori:	Peña, Ike dela, Borlongan, Cesar, Shen, Guofang, Davis, Willie
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Korea (South) Korean Stroke Society 01.01.2017 대한뇌졸중학회
Predmet:	blood-brain barrier hemorrhage Review tissue plasminogen activator vasculature 신경과학 Blood-brain barrier Tissue plasminogen activator Hemorrhage Vasculature
ISSN:	2287-6391, 1229-4101, 2287-6405
On-line prístup:	Získať plný text
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