Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need

To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant mor...

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Veröffentlicht in:	Journal of stroke Jg. 19; H. 1; S. 50 - 60
Hauptverfasser:	Peña, Ike dela, Borlongan, Cesar, Shen, Guofang, Davis, Willie
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Korea (South) Korean Stroke Society 01.01.2017 대한뇌졸중학회
Schlagworte:	blood-brain barrier hemorrhage Review tissue plasminogen activator vasculature 신경과학 Blood-brain barrier Tissue plasminogen activator Hemorrhage Vasculature
ISSN:	2287-6391, 1229-4101, 2287-6405
Online-Zugang:	Volltext
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