Computational modelling of wounded tissue subject to negative pressure wound therapy following trans-femoral amputation

Proof-of-concept computational models were developed and applied as tools to gain insights into biomechanical interactions and variations of oxygen gradients of wounded tissue subject to negative pressure wound therapy (NPWT), following trans-femoral amputation. A macro-scale finite-element model of...

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Bibliographic Details
Published in:	Biomechanics and modeling in mechanobiology Vol. 16; no. 6; pp. 1819 - 1832
Main Authors:	Zeybek, B., Li, S., Fernandez, J. W., Stapley, S., Silberschmidt, V. V., Liu, Y.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2017 Springer Nature B.V
Subjects:	Amputation Biological and Medical Physics Biomechanics Biomedical Engineering and Bioengineering Biophysics Boundary conditions Computation Computed tomography Computer applications Computer based modeling Computer Simulation Contraction Deformation Diffusion Engineering Femur Femur - drug effects Femur - surgery Finite element method Image Processing, Computer-Assisted Mathematical analysis Mathematical models Multiscale analysis Muscles - drug effects Muscles - pathology Negative-Pressure Wound Therapy Original Paper Oxygen - pharmacology Oxygenation Pressure Pressure ulcers Reactive oxygen species Scale models Software Spatial distribution Theoretical and Applied Mechanics Therapy Tissues Weight-Bearing Wound Healing Wounds Biomechanics Finite-element analysis Negative pressure wound therapy Tissue oxygenation
ISSN:	1617-7959, 1617-7940, 1617-7940
Online Access:	Get full text
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