MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling

In order to identify new markers of vascular cell senescence with potential in vivo implications, primary cultured endothelial cells, including human umbilical vein endothelial cells (HUVECs), human aortic endothelial cells (HAECs), human coronary artery endothelial cells (HCAECs) and ex vivo circul...

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Bibliographic Details
Published in:	AGE Vol. 35; no. 4; pp. 1157 - 1172
Main Authors:	Olivieri, Fabiola, Lazzarini, Raffaella, Recchioni, Rina, Marcheselli, Fiorella, Rippo, Maria Rita, Di Nuzzo, Silvia, Albertini, Maria Cristina, Graciotti, Laura, Babini, Lucia, Mariotti, Serena, Spada, Giorgio, Abbatecola, Angela Marie, Antonicelli, Roberto, Franceschi, Claudio, Procopio, Antonio Domenico
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.08.2013 Springer Nature B.V
Subjects:	Age Aging Biomarkers Biomarkers - metabolism Biomedical and Life Sciences Cardiovascular disease Cell Biology Cells, Cultured Cellular Senescence - genetics Claudin-1 - genetics Claudin-1 - metabolism Coronary vessels Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Gene expression Gene Expression Regulation Genes Genotype & phenotype Geriatrics Geriatrics/Gerontology Heart failure Heart Failure - genetics Heart Failure - metabolism Heart Failure - pathology Humans Inflammation - genetics Inflammation - metabolism Inflammation - pathology Kinases Life Sciences Medical research MicroRNAs MicroRNAs - biosynthesis MicroRNAs - genetics Molecular Medicine Pathology Patients Real-Time Polymerase Chain Reaction Research subjects RNA - genetics Senescence Signal Transduction - genetics Statistical analysis Studies Telomerase Telomere - genetics Telomere - metabolism Tissue Array Analysis Tumor necrosis factor-TNF MiR-146a Circulating angiogenic cells Congestive heart failure Toll-like receptor pathway Vascular senescence
ISSN:	0161-9152, 2509-2715, 1574-4647, 1574-4647, 2509-2723
Online Access:	Get full text
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