Cognitive impairment in the population-based ural very old study

Background: Despite its marked importance in public health, the prevalence of cognitive impairment (CI) and its associated factors have only rarely been examined in old populations in general or in Russia at all. Objective: To assess CI prevalence and its determinants in a very elderly population in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Frontiers in aging neuroscience Ročník 14; s. 912755
Hlavní autoři: Bikbov, Mukharram M., Kazakbaeva, Gyulli M., Iakupova, Ellina M., Panda-Jonas, Songhomitra, Fakhretdinova, Albina A., Tuliakova, Azaliia M., Rusakova, Iuliia A., Jonas, Jost B.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Lausanne Frontiers Research Foundation 19.07.2022
Frontiers Media S.A
Témata:
Acuity
Age
Aging Neuroscience
Alzheimer's disease
Chronic obstructive pulmonary disease
Cognitive ability
cognitive impairment
Dementia
Employees
Hearing loss
Mini-Mental State Examination
Older people
Outdoor air quality
Paramedics
Participation
Physical activity
Population
Population studies
Population-based studies
population-based study
Postal & delivery services
Public health
Questionnaires
Research centers
Retirement homes
Ural Very Old Study
Russia
ISSN:1663-4365, 1663-4365
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Background: Despite its marked importance in public health, the prevalence of cognitive impairment (CI) and its associated factors have only rarely been examined in old populations in general or in Russia at all. Objective: To assess CI prevalence and its determinants in a very elderly population in Russia. Methods: The population-based Ural Very Old Study, conducted in rural and urban region in Bashkortostan/Russia, included 1526 (81.1%) out of 1882 eligible individuals aged 85+ years. A series of medical examinations including the Mini-Mental State Examination (MMSE) for the assessment of CI was performed. Results: MMSE data were available for 1442 (94.5%) individuals (mean age:88.3±2.9 years; range:85-103 years). The median MMSE score was 24 (interquartile range:19, 27). Prevalence of any CI (MMSE score <24 points) was 701/1442 (48.6%; 95% confidence interval (CI): 46.0, 51.2). Prevalence of mild, moderate and severe CI (MMSE score 19-23 points,10-18 points, and ≤9 points,respectively) was 357/1442 (24.8%; 95%CI: 22.5, 27.0), 246/1442 (17.1%; 95%CI: 15.1, 19.0), and 98/1442 (6.8%; 95%CI: 5.5, 8.1), resp.. A lower MMSE score correlated (regression coefficient r2:0.31) with older age (beta:-0.13; P<0.001), rural region of habitation (beta:0.15; P<0.001), lower level of education (beta:0.19; P<0.001), higher depression score (beta:-0.33; P<0.001) (or alternatively, higher prevalence of hearing loss (beta:-0.10; P=0.001), worse visual acuity (beta:-0.10; P=0.001), and lower physical activity (beta:0.06; P=0.04). Conclusions: In this elderly study population from rural and urban Russia, prevalence of any, mild, moderate and severe CI was 48.6%, 24.8%, 17.1%, and 6.8%, resp.. Besides medical and lifestyle factors, vision and hearing impairment were major factors associated with CI.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
This article was submitted to Alzheimer’s Disease and Related Dementias, a section of the journal Frontiers in Aging Neuroscience
Edited by: Carol Brayne, University of Cambridge, United Kingdom
Reviewed by: James C. Vickers, University of Tasmania, Australia; Maria Skaalum Petersen, University of the Faroe Islands, Faroe Islands; Lei Feng, National University of Singapore, Singapore; Leon Flicker, University of Western Australia, Australia
ISSN:1663-4365
1663-4365
DOI:10.3389/fnagi.2022.912755