The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study

The disposition of intramuscular artemether (AM) was studied in 26 Kenyan children with cerebral malaria. Antimalarial activity determined by bioassay was compared with total plasma AM plus dihydroartemisinin (DHA) determined by high power liquid chromatography (HPLC). Therapeutic levels were achiev...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene Jg. 91; H. 3; S. 331
Hauptverfasser:	Murphy, S A, Mberu, E, Muhia, D, English, M, Crawley, J, Waruiru, C, Lowe, B, Newton, C R, Winstanley, P, Marsh, K, Watkins, W M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.05.1997
Schlagworte:	Antimalarials - administration & dosage Antimalarials - blood Antimalarials - pharmacokinetics Artemether Artemisinins Biological Availability Child Child, Preschool Chromatography, High Pressure Liquid Female Humans Infant Injections, Intramuscular Kenya Malaria, Cerebral - blood Malaria, Cerebral - drug therapy Male Respiratory Insufficiency - complications Sesquiterpenes - administration & dosage Sesquiterpenes - blood Sesquiterpenes - pharmacokinetics Time Factors Treatment Outcome
ISSN:	0035-9203
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!