Arenavirus Z-glycoprotein association requires Z myristoylation but not functional RING or late domains

Generation of infectious arenavirus-like particles requires the virus RING finger Z protein and surface glycoprotein precursor (GPC) and the correct processing of GPC into GP1, GP2, and a stable signal peptide (SSP). Z is the driving force of arenavirus budding, whereas the GP complex (GPc), consist...

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Veröffentlicht in:	Journal of virology Jg. 81; H. 17; S. 9451
Hauptverfasser:	Capul, Althea A, Perez, Mar, Burke, Emily, Kunz, Stefan, Buchmeier, Michael J, de la Torre, Juan C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2007
Schlagworte:	Animals Arenavirus - physiology Carrier Proteins - chemistry Carrier Proteins - metabolism Cell Line Cytoplasm - chemistry Glycoproteins - chemistry Glycoproteins - metabolism Immunoprecipitation Microscopy, Confocal Protein Binding Protein Processing, Post-Translational Viral Envelope Proteins - chemistry Viral Envelope Proteins - metabolism Viral Matrix Proteins - metabolism Viral Proteins - chemistry Viral Proteins - metabolism Virus Assembly - physiology
ISSN:	0022-538X
Online-Zugang:	Weitere Angaben
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